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CAZyme Information: MGYG000004226_00084
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | CAG-533 sp900553855 | |||||||||||
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| Lineage | Bacteria; Firmicutes; Bacilli; RF39; UBA660; CAG-533; CAG-533 sp900553855 | |||||||||||
| CAZyme ID | MGYG000004226_00084 | |||||||||||
| CAZy Family | GT4 | |||||||||||
| CAZyme Description | Glycogen synthase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 84886; End: 86703 Strand: - | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd03801 | GT4_PimA-like | 1.54e-31 | 158 | 491 | 9 | 344 | phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea. |
| COG0438 | RfaB | 8.15e-26 | 161 | 491 | 13 | 353 | Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]. |
| pfam00534 | Glycos_transf_1 | 2.99e-20 | 338 | 491 | 1 | 155 | Glycosyl transferases group 1. Mutations in this domain of PIGA lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family. |
| cd03798 | GT4_WlbH-like | 4.71e-19 | 313 | 507 | 173 | 366 | Bordetella parapertussis WlbH and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS. |
| pfam13692 | Glyco_trans_1_4 | 4.43e-18 | 339 | 480 | 1 | 138 | Glycosyl transferases group 1. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AQS58807.1 | 2.92e-124 | 116 | 583 | 372 | 844 |
| QJD85497.1 | 8.78e-115 | 133 | 586 | 452 | 909 |
| QMV41944.1 | 9.31e-114 | 133 | 586 | 452 | 909 |
| QTH42384.1 | 7.10e-108 | 133 | 507 | 452 | 824 |
| AVM43205.1 | 2.83e-67 | 142 | 507 | 222 | 581 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6ME2_A | 1.67e-07 | 366 | 501 | 271 | 407 | XFELcrystal structure of human melatonin receptor MT1 in complex with ramelteon [Homo sapiens] |
| 6ME3_A | 1.67e-07 | 366 | 501 | 271 | 407 | XFELcrystal structure of human melatonin receptor MT1 in complex with 2-phenylmelatonin [Homo sapiens],6ME4_A XFEL crystal structure of human melatonin receptor MT1 in complex with 2-iodomelatonin [Homo sapiens],6ME5_A XFEL crystal structure of human melatonin receptor MT1 in complex with agomelatine [Homo sapiens],6PS8_A XFEL MT1R structure by ligand exchange from agomelatine to 2-phenylmelatonin. [Homo sapiens] |
| 6KP6_A | 2.17e-07 | 366 | 506 | 268 | 409 | Thestructural study of mutation induced inactivation of Human muscarinic receptor M4 [Homo sapiens] |
| 5I45_A | 2.40e-07 | 412 | 511 | 109 | 208 | 1.35Angstrom Crystal Structure of C-terminal Domain of Glycosyl Transferase Group 1 Family Protein (LpcC) from Francisella tularensis. [Francisella tularensis subsp. tularensis SCHU S4] |
| 2BFW_A | 2.56e-07 | 366 | 499 | 66 | 200 | Structureof the C domain of glycogen synthase from Pyrococcus abyssi [Pyrococcus abyssi] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P26470 | 4.42e-10 | 326 | 503 | 173 | 364 | Lipopolysaccharide 1,2-N-acetylglucosaminetransferase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=waaK PE=3 SV=1 |
| Q58577 | 8.86e-10 | 361 | 505 | 194 | 337 | Uncharacterized glycosyltransferase MJ1178 OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) OX=243232 GN=MJ1178 PE=3 SV=1 |
| Q8FSH1 | 3.62e-08 | 404 | 499 | 295 | 390 | D-inositol 3-phosphate glycosyltransferase OS=Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395) OX=196164 GN=mshA PE=3 SV=1 |
| A4QB40 | 2.39e-06 | 404 | 499 | 295 | 390 | D-inositol 3-phosphate glycosyltransferase OS=Corynebacterium glutamicum (strain R) OX=340322 GN=mshA PE=3 SV=1 |
| Q8NTA6 | 2.39e-06 | 404 | 499 | 295 | 390 | D-inositol 3-phosphate glycosyltransferase OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) OX=196627 GN=mshA PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000049 | 0.000001 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |