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CAZyme Information: MGYG000004245_00014
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | SFEL01 sp004557245 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; CAG-138; SFEL01; SFEL01 sp004557245 | |||||||||||
| CAZyme ID | MGYG000004245_00014 | |||||||||||
| CAZy Family | GT39 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 14308; End: 18015 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT39 | 819 | 1042 | 8.9e-53 | 0.9192825112107623 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam16192 | PMT_4TMC | 1.11e-25 | 1055 | 1228 | 4 | 198 | C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes. |
| COG1928 | PMT1 | 6.52e-20 | 1058 | 1232 | 505 | 695 | Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]. |
| COG5542 | COG5542 | 9.48e-16 | 283 | 581 | 82 | 369 | Mannosyltransferase related to Gpi18 [Carbohydrate transport and metabolism]. |
| COG4346 | COG4346 | 3.34e-13 | 834 | 1107 | 122 | 351 | Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase [Posttranslational modification, protein turnover, chaperones]. |
| pfam02366 | PMT | 4.96e-13 | 817 | 991 | 16 | 204 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| CQR52353.1 | 2.26e-254 | 2 | 1232 | 6 | 1275 |
| QSF45552.1 | 4.23e-254 | 2 | 1232 | 6 | 1273 |
| QWT55655.1 | 1.58e-252 | 49 | 1232 | 37 | 1253 |
| QGQ95357.1 | 3.72e-250 | 39 | 1232 | 49 | 1279 |
| QWU18200.1 | 9.60e-249 | 29 | 1232 | 34 | 1273 |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| L8F4Z2 | 6.75e-29 | 824 | 1230 | 67 | 515 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1 |
| P9WN04 | 9.84e-28 | 824 | 1230 | 73 | 521 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2 |
| P9WN05 | 9.84e-28 | 824 | 1230 | 73 | 521 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2 |
| Q8NRZ6 | 3.56e-18 | 847 | 1230 | 99 | 519 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) OX=196627 GN=pmt PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000781 | 0.994573 | 0.003960 | 0.000266 | 0.000192 | 0.000185 |
TMHMM Annotations download full data without filtering help
| start | end |
|---|---|
| 4 | 23 |
| 204 | 226 |
| 241 | 263 |
| 284 | 306 |
| 321 | 343 |
| 356 | 378 |
| 403 | 425 |
| 437 | 459 |
| 512 | 529 |
| 536 | 555 |
| 559 | 576 |
| 583 | 602 |
| 612 | 634 |
| 675 | 697 |
| 866 | 888 |
| 917 | 936 |
| 956 | 987 |
| 1017 | 1039 |
| 1111 | 1130 |
| 1137 | 1156 |
| 1160 | 1179 |
| 1199 | 1221 |