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CAZyme Information: MGYG000004272_01224
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | UMGS915 sp900546795 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_C; Negativicutes; Veillonellales; Megasphaeraceae; UMGS915; UMGS915 sp900546795 | |||||||||||
| CAZyme ID | MGYG000004272_01224 | |||||||||||
| CAZy Family | GT83 | |||||||||||
| CAZyme Description | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 3913; End: 5478 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT83 | 8 | 457 | 3.5e-113 | 0.8648148148148148 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG1807 | ArnT | 7.70e-58 | 4 | 344 | 3 | 353 | 4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family [Cell wall/membrane/envelope biogenesis]. |
| PRK13279 | arnT | 1.57e-35 | 9 | 331 | 6 | 337 | lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase. |
| pfam13231 | PMT_2 | 3.53e-15 | 64 | 176 | 1 | 120 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366. |
| pfam02366 | PMT | 1.01e-10 | 13 | 220 | 2 | 235 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
| COG4346 | COG4346 | 0.002 | 88 | 324 | 158 | 406 | Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase [Posttranslational modification, protein turnover, chaperones]. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AXL21031.1 | 9.22e-150 | 1 | 520 | 1 | 517 |
| AVO73979.1 | 2.10e-148 | 1 | 520 | 1 | 517 |
| CCC72524.1 | 2.10e-148 | 1 | 520 | 1 | 517 |
| ALG41392.1 | 2.98e-148 | 1 | 520 | 1 | 517 |
| AVO26796.1 | 2.98e-148 | 1 | 520 | 1 | 517 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5EZM_A | 3.86e-32 | 4 | 354 | 27 | 390 | CrystalStructure of ArnT from Cupriavidus metallidurans in the apo state [Cupriavidus metallidurans CH34],5F15_A Crystal Structure of ArnT from Cupriavidus metallidurans bound to Undecaprenyl phosphate [Cupriavidus metallidurans CH34] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| B4ETL9 | 3.26e-33 | 13 | 359 | 12 | 368 | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 2 OS=Proteus mirabilis (strain HI4320) OX=529507 GN=arnT2 PE=3 SV=1 |
| C5BDQ8 | 1.49e-32 | 17 | 359 | 10 | 363 | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Edwardsiella ictaluri (strain 93-146) OX=634503 GN=arnT PE=3 SV=1 |
| O67270 | 1.02e-31 | 26 | 328 | 20 | 322 | Uncharacterized protein aq_1220 OS=Aquifex aeolicus (strain VF5) OX=224324 GN=aq_1220 PE=3 SV=1 |
| A0KGY4 | 4.63e-30 | 23 | 324 | 17 | 327 | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049) OX=380703 GN=arnT PE=3 SV=1 |
| A1JPM4 | 4.89e-30 | 14 | 326 | 11 | 333 | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081) OX=393305 GN=arnT PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.999977 | 0.000036 | 0.000002 | 0.000000 | 0.000000 | 0.000011 |
TMHMM Annotations download full data without filtering help
| start | end |
|---|---|
| 13 | 32 |
| 80 | 102 |
| 115 | 137 |
| 157 | 188 |
| 201 | 223 |
| 252 | 274 |
| 286 | 303 |
| 308 | 327 |
| 340 | 362 |
| 372 | 391 |
| 398 | 417 |