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CAZyme Information: MGYG000004275_00251

You are here: Home > Sequence: MGYG000004275_00251

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Ruminococcus_C sp000437175
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; Ruminococcus_C; Ruminococcus_C sp000437175
CAZyme ID MGYG000004275_00251
CAZy Family GH48
CAZyme Description Cellulose 1,4-beta-cellobiosidase (reducing end) CelS
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
979 MGYG000004275_7|CGC1 105835.53 4.2352
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004275 2279760 MAG China Asia
Gene Location Start: 23093;  End: 26032  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.-

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH48 45 546 2.8e-169 0.7414075286415712

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam02011 Glyco_hydro_48 0.0 45 790 1 620
Glycosyl hydrolase family 48. Members of this family are endoglucanase EC:3.2.1.4 and exoglucanase EC:3.2.1.91 enzymes that cleave cellulose or related substrate.
cd14256 Dockerin_I 4.24e-11 915 971 1 57
Type I dockerin repeat domain. Bacterial cohesin domains bind to a complementary protein domain named dockerin, and this interaction is required for the formation of the cellulosome, a cellulose-degrading complex. The cellulosome consists of scaffoldin, a noncatalytic scaffolding polypeptide, that comprises repeating cohesion modules and a single carbohydrate-binding module (CBM). Specific calcium-dependent interactions between cohesins and dockerins appear to be essential for cellulosome assembly. This subfamily represents type I dockerins, which are responsible for anchoring a variety of enzymatic domains to the complex.
pfam02368 Big_2 3.44e-09 806 870 5 77
Bacterial Ig-like domain (group 2). This family consists of bacterial domains with an Ig-like fold. Members of this family are found in bacterial and phage surface proteins such as intimins.
cd14253 Dockerin 1.15e-06 916 971 1 56
Dockerin repeat domain. Dockerins are modules in the cellulosome complex that often anchor catalytic subunits by binding to cohesin domains of scaffolding proteins. Three types of dockerins and their corresponding cohesin have been described in the literature. This alignment models two consecutive dockerin repeats, the functional unit.
smart00635 BID_2 1.27e-06 800 870 1 81
Bacterial Ig-like domain 2.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
CBL17316.1 7.09e-298 1 800 1 727
AAR01217.1 7.09e-268 7 817 2 794
CAS03459.1 7.19e-267 4 792 4 778
ADU23081.1 1.88e-262 4 793 4 779
BAJ05814.1 1.88e-262 4 793 4 779

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
1L1Y_A 4.19e-163 13 799 10 673
ChainA, cellobiohydrolase [Acetivibrio thermocellus],1L1Y_B Chain B, cellobiohydrolase [Acetivibrio thermocellus],1L1Y_C Chain C, cellobiohydrolase [Acetivibrio thermocellus],1L1Y_D Chain D, cellobiohydrolase [Acetivibrio thermocellus],1L1Y_E Chain E, cellobiohydrolase [Acetivibrio thermocellus],1L1Y_F Chain F, cellobiohydrolase [Acetivibrio thermocellus],1L2A_A Chain A, cellobiohydrolase [Acetivibrio thermocellus],1L2A_B Chain B, cellobiohydrolase [Acetivibrio thermocellus],1L2A_C Chain C, cellobiohydrolase [Acetivibrio thermocellus],1L2A_D Chain D, cellobiohydrolase [Acetivibrio thermocellus],1L2A_E Chain E, cellobiohydrolase [Acetivibrio thermocellus],1L2A_F Chain F, cellobiohydrolase [Acetivibrio thermocellus]
6D5D_A 9.03e-162 41 790 16 642
Structureof Caldicellulosiruptor danielii GH48 module of glycoside hydrolase WP_045175321 [Caldicellulosiruptor danielii]
5YJ6_A 4.87e-161 35 792 3 636
ChainA, Dockerin type I repeat-containing protein [Acetivibrio thermocellus DSM 1313]
4EL8_A 2.36e-158 45 790 9 631
Theunliganded structure of C.bescii CelA GH48 module [Caldicellulosiruptor bescii DSM 6725]
4L0G_A 4.71e-158 45 790 13 635
CrystalStructure of a GH48 cellobiohydrolase from Caldicellulosiruptor bescii [Caldicellulosiruptor bescii DSM 6725],4L6X_A Crystal Structure of a GH48 cellobiohydrolase from Caldicellulosiruptor bescii [Caldicellulosiruptor bescii DSM 6725],4TXT_A Crystal Structure of a GH48 cellobiohydrolase from Caldicellulosiruptor bescii [Caldicellulosiruptor bescii DSM 6725]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
A3DH67 5.71e-162 13 813 10 694
Cellulose 1,4-beta-cellobiosidase (reducing end) CelS OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=celS PE=1 SV=1
P0C2S5 5.71e-162 13 813 10 694
Cellulose 1,4-beta-cellobiosidase (reducing end) CelS OS=Acetivibrio thermocellus OX=1515 GN=celS PE=1 SV=1
P37698 1.52e-155 4 815 3 681
Endoglucanase F OS=Ruminiclostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10) OX=394503 GN=celCCF PE=1 SV=2
P50900 5.37e-152 39 821 34 680
Exoglucanase-2 OS=Thermoclostridium stercorarium (strain ATCC 35414 / DSM 8532 / NCIMB 11754) OX=1121335 GN=celY PE=1 SV=2
P22534 1.78e-147 41 790 1113 1739
Endoglucanase A OS=Caldicellulosiruptor saccharolyticus OX=44001 GN=celA PE=3 SV=2

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000442 0.877446 0.121216 0.000325 0.000296 0.000239

TMHMM  Annotations      download full data without filtering help

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