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CAZyme Information: MGYG000004275_00504
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Ruminococcus_C sp000437175 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; Ruminococcus_C; Ruminococcus_C sp000437175 | |||||||||||
| CAZyme ID | MGYG000004275_00504 | |||||||||||
| CAZy Family | CBM4 | |||||||||||
| CAZyme Description | Cellulose 1,4-beta-cellobiosidase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 11474; End: 14581 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH9 | 362 | 898 | 1.3e-109 | 0.9880382775119617 |
| CBM4 | 41 | 216 | 5.3e-20 | 0.9761904761904762 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam00759 | Glyco_hydro_9 | 2.50e-81 | 363 | 898 | 2 | 374 | Glycosyl hydrolase family 9. |
| cd02850 | E_set_Cellulase_N | 1.82e-20 | 263 | 349 | 4 | 86 | N-terminal Early set domain associated with the catalytic domain of cellulase. E or "early" set domains are associated with the catalytic domain of cellulases at the N-terminal end. Cellulases are O-glycosyl hydrolases (GHs) that hydrolyze beta 1-4 glucosidic bonds in cellulose. They are usually categorized into either exoglucanases, which sequentially release terminal sugar units from the cellulose chain, or endoglucanases, which also attack the chain internally. The N-terminal domain of cellulase may be related to the immunoglobulin and/or fibronectin type III superfamilies. These domains are associated with different types of catalytic domains at either the N-terminal or C-terminal end and may be involved in homodimeric/tetrameric/dodecameric interactions. Members of this family include members of the alpha amylase family, sialidase, galactose oxidase, cellulase, cellulose, hyaluronate lyase, chitobiase, and chitinase, among others. |
| pfam02927 | CelD_N | 2.78e-19 | 261 | 344 | 3 | 83 | Cellulase N-terminal ig-like domain. |
| PLN03009 | PLN03009 | 2.30e-11 | 364 | 900 | 33 | 487 | cellulase |
| cd14256 | Dockerin_I | 9.12e-10 | 971 | 1027 | 1 | 57 | Type I dockerin repeat domain. Bacterial cohesin domains bind to a complementary protein domain named dockerin, and this interaction is required for the formation of the cellulosome, a cellulose-degrading complex. The cellulosome consists of scaffoldin, a noncatalytic scaffolding polypeptide, that comprises repeating cohesion modules and a single carbohydrate-binding module (CBM). Specific calcium-dependent interactions between cohesins and dockerins appear to be essential for cellulosome assembly. This subfamily represents type I dockerins, which are responsible for anchoring a variety of enzymatic domains to the complex. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| CBL17684.1 | 5.20e-247 | 1 | 1017 | 1 | 932 |
| BAH56283.1 | 1.18e-221 | 41 | 902 | 176 | 1007 |
| ADU21576.1 | 1.81e-216 | 37 | 900 | 30 | 798 |
| AAR01216.1 | 3.73e-211 | 33 | 916 | 24 | 916 |
| CAS03458.1 | 9.23e-210 | 33 | 905 | 28 | 906 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 1UT9_A | 5.43e-134 | 261 | 902 | 7 | 605 | ChainA, CELLULOSE 1,4-BETA-CELLOBIOSIDASE [Acetivibrio thermocellus] |
| 1RQ5_A | 1.54e-133 | 261 | 904 | 7 | 607 | ChainA, Cellobiohydrolase [Acetivibrio thermocellus] |
| 6DHT_A | 1.39e-52 | 261 | 902 | 18 | 565 | Bacteroidesovatus GH9 Bacova_02649 [Bacteroides ovatus ATCC 8483] |
| 5U0H_A | 3.26e-48 | 275 | 905 | 7 | 544 | Crystalstructure of GH family 9 endoglucanase J30 [Thermobacillus composti KWC4] |
| 3X17_A | 3.57e-47 | 263 | 899 | 20 | 554 | Crystalstructure of metagenome-derived glycoside hydrolase family 9 endoglucanase [uncultured bacterium],3X17_B Crystal structure of metagenome-derived glycoside hydrolase family 9 endoglucanase [uncultured bacterium] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| A3DCH1 | 5.38e-156 | 43 | 903 | 45 | 813 | Cellulose 1,4-beta-cellobiosidase OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=celK PE=3 SV=1 |
| P0C2S1 | 5.38e-156 | 43 | 903 | 45 | 813 | Cellulose 1,4-beta-cellobiosidase OS=Acetivibrio thermocellus OX=1515 GN=celK PE=1 SV=1 |
| Q05156 | 2.26e-114 | 53 | 905 | 46 | 746 | Cellulase 1 OS=Streptomyces reticuli OX=1926 GN=cel1 PE=1 SV=1 |
| P14090 | 2.02e-112 | 53 | 905 | 196 | 911 | Endoglucanase C OS=Cellulomonas fimi (strain ATCC 484 / DSM 20113 / JCM 1341 / NBRC 15513 / NCIMB 8980 / NCTC 7547) OX=590998 GN=cenC PE=1 SV=2 |
| P10476 | 1.59e-103 | 263 | 905 | 39 | 602 | Endoglucanase A OS=Cellvibrio japonicus (strain Ueda107) OX=498211 GN=celA PE=3 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.092129 | 0.905532 | 0.000775 | 0.000978 | 0.000291 | 0.000277 |
