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CAZyme Information: MGYG000004314_00835
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Varibaculum timonense | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Actinobacteriota; Actinomycetia; Actinomycetales; Actinomycetaceae; Varibaculum; Varibaculum timonense | |||||||||||
| CAZyme ID | MGYG000004314_00835 | |||||||||||
| CAZy Family | GT39 | |||||||||||
| CAZyme Description | putative dolichyl-phosphate-mannose--protein mannosyltransferase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 38047; End: 39777 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT39 | 71 | 349 | 5.3e-64 | 0.9910313901345291 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG1928 | PMT1 | 1.34e-17 | 45 | 285 | 4 | 223 | Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]. |
| pfam16192 | PMT_4TMC | 2.10e-11 | 384 | 573 | 11 | 198 | C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes. |
| pfam02366 | PMT | 1.83e-10 | 134 | 286 | 42 | 197 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
| COG4346 | COG4346 | 4.63e-10 | 137 | 498 | 136 | 405 | Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase [Posttranslational modification, protein turnover, chaperones]. |
| COG1807 | ArnT | 1.79e-09 | 73 | 286 | 15 | 193 | 4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family [Cell wall/membrane/envelope biogenesis]. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QOX81378.1 | 3.04e-145 | 44 | 576 | 31 | 547 |
| QQC43974.1 | 6.89e-124 | 65 | 576 | 72 | 584 |
| QQT14111.1 | 7.88e-124 | 65 | 574 | 20 | 545 |
| QQU09498.1 | 7.88e-124 | 65 | 574 | 20 | 545 |
| ADI66786.1 | 7.88e-124 | 65 | 574 | 20 | 545 |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P9WN04 | 7.11e-72 | 59 | 575 | 38 | 521 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2 |
| P9WN05 | 7.11e-72 | 59 | 575 | 38 | 521 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2 |
| L8F4Z2 | 8.99e-71 | 59 | 575 | 32 | 515 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1 |
| Q8NRZ6 | 3.41e-52 | 65 | 575 | 38 | 519 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) OX=196627 GN=pmt PE=3 SV=1 |
| Q5A688 | 5.82e-09 | 29 | 284 | 52 | 298 | Dolichyl-phosphate-mannose--protein mannosyltransferase 6 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=PMT6 PE=2 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.999657 | 0.000317 | 0.000017 | 0.000002 | 0.000001 | 0.000011 |
TMHMM Annotations download full data without filtering help
| start | end |
|---|---|
| 64 | 83 |
| 157 | 174 |
| 181 | 203 |
| 208 | 230 |
| 251 | 270 |
| 275 | 297 |
| 321 | 343 |
| 435 | 454 |
| 461 | 478 |
| 482 | 504 |
| 534 | 556 |