CAZyme Information: MGYG000004365_01453

Basic Information

• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Muribaculaceae; UBA7173
• CAZyme ID: MGYG000004365_01453
• CAZy Family: GH115
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
885	MGYG000004365_45|CGC1	98930.14	5.3664

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000004365	2654246	MAG	Israel	Asia

• Gene Location: Start: 11732; End: 14389 Strand: +

Full Sequence      

MKYRILTILLVLFGTAAGLQAIDNPGITQPTLADGRFTLINAGVPASILVDSTDNVGVRI
AARNLSADFGRVCGKDAALINEPAAGQTIIVGTLDCKFIKALVKAGKIDEKSLKGKTEKY
ILTTVANPFEGIDKTVAGNAPAGVKEALVIAGSDRRGAIYGIYELSEQIGVSPWYDWADV
PVVHQDNLSIAGGEYTAGEPAVRYRGIFLNDEAPCLTSWVENTYGTKYGDHRFYGRVFEL
LLRLRGNFMWPAMWGWSFYADDPENSKTADDMGIIMGTSHHEPMARNHQEWARNRGKYGV
WDYANNQKVIDKFFREGIERCASTEDLITIGMRGDGDTSMGGKEGKDDEAADLDDYNMKL
LRKIFKNQRKIIADVTGEKAEKRPQVWALYKEVQNYYDKGLSVPDDVIMLVCDDNWGNVR
KLPNAEERKHPGGWGMYYHVDYVGAPRNSKWLNCTPPQNLCEQMRLTYDYGVDKLWILNV
GDLKPMEYPITLFLDMAWNPTKFRAPEVTAHLRDFCARQFGEAQADEAARILNLQCKYAG
RVTPEMLDAKTYNVSTGEWKQVADDYARLEAEALRQYLTLDPTARDAYKQLILFPVQAMS
NLYDMYYAQAMNHKLYAENNPRANEWADRVERDFARDAALCLDYNKNMAGGKWDGMMTQK
HIGYTSWHDGFEADTLPEIFRVGDTAPGHYVFSAADGVVAIEAEHFNSAEAPEGTEWTVI
PYMGRTLSGVSLTPYDKPAGGSALKYKMQVSNAPDSLDVLVVVKSTLAFANPEGHRFAIG
FEGAPEKIVNFNGELNEKQENVYRITYPTVARRVIENKVRLAVPGGSEKSADGKFMLTLV
IKPLEPGTVFEKIVVDCGGYQKSYLHMPESPCRRELPNSSELARE

Enzyme Prediction     

EC	3.2.1.131

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH115	35	853	1.1e-270	0.9971305595408895

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam15979	Glyco_hydro_115	0.0	198	546	1	334	Glycosyl hydrolase family 115. Glyco_hydro_115 is a family of glycoside hydrolases likely to have the activity of xylan a-1,2-glucuronidase, EC:3.2.1.131, or a-(4-O-methyl)-glucuronidase EC:3.2.1.-.
pfam17829	GH115_C	1.98e-35	691	869	1	172	Gylcosyl hydrolase family 115 C-terminal domain. This domain is found at the C-terminus of glycosyl hydrolase family 115 proteins. This domain has a beta-sandwich fold.
pfam03648	Glyco_hydro_67N	4.61e-04	45	165	21	120	Glycosyl hydrolase family 67 N-terminus. Alpha-glucuronidases, components of an ensemble of enzymes central to the recycling of photosynthetic biomass, remove the alpha-1,2 linked 4-O-methyl glucuronic acid from xylans. This family represents the N-terminal region of alpha-glucuronidase. The N-terminal domain forms a two-layer sandwich, each layer being formed by a beta sheet of five strands. A further two helices form part of the interface with the central, catalytic, module (pfam07488).

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ADD61499.1	0.0	10	875	10	859
QUT56984.1	0.0	21	878	21	862
ABR37760.1	0.0	21	878	21	862
QQY39902.1	0.0	21	878	21	862
QQY43189.1	0.0	21	878	21	862

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4C90_A	0.0	31	875	38	854	Evidencethat GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C90_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_A Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus]
7PUG_A	0.0	23	874	3	838	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
7PXQ_A	0.0	23	874	2	837	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
4ZMH_A	8.39e-169	33	669	10	622	Crystalstructure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40],4ZMH_B Crystal structure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40]
6NPS_A	1.93e-114	57	669	31	647	Crystalstructure of GH115 enzyme AxyAgu115A from Amphibacillus xylanus [Amphibacillus xylanus NBRC 15112],6NPS_B Crystal structure of GH115 enzyme AxyAgu115A from Amphibacillus xylanus [Amphibacillus xylanus NBRC 15112]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000762	0.998433	0.000271	0.000187	0.000165	0.000165

TMHMM  Annotations     

There is no transmembrane helices in MGYG000004365_01453.