You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000004384_00862
You are here: Home > Sequence: MGYG000004384_00862
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; Ruminococcus; | |||||||||||
| CAZyme ID | MGYG000004384_00862 | |||||||||||
| CAZy Family | CBM4 | |||||||||||
| CAZyme Description | Cellulose 1,4-beta-cellobiosidase | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 9681; End: 12731 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH9 | 354 | 913 | 2.5e-100 | 0.9880382775119617 |
| CBM4 | 37 | 178 | 1e-20 | 0.9603174603174603 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam00759 | Glyco_hydro_9 | 1.82e-53 | 354 | 912 | 1 | 373 | Glycosyl hydrolase family 9. |
| cd02850 | E_set_Cellulase_N | 1.06e-23 | 244 | 343 | 2 | 86 | N-terminal Early set domain associated with the catalytic domain of cellulase. E or "early" set domains are associated with the catalytic domain of cellulases at the N-terminal end. Cellulases are O-glycosyl hydrolases (GHs) that hydrolyze beta 1-4 glucosidic bonds in cellulose. They are usually categorized into either exoglucanases, which sequentially release terminal sugar units from the cellulose chain, or endoglucanases, which also attack the chain internally. The N-terminal domain of cellulase may be related to the immunoglobulin and/or fibronectin type III superfamilies. These domains are associated with different types of catalytic domains at either the N-terminal or C-terminal end and may be involved in homodimeric/tetrameric/dodecameric interactions. Members of this family include members of the alpha amylase family, sialidase, galactose oxidase, cellulase, cellulose, hyaluronate lyase, chitobiase, and chitinase, among others. |
| pfam02927 | CelD_N | 3.25e-22 | 244 | 335 | 3 | 82 | Cellulase N-terminal ig-like domain. |
| pfam02018 | CBM_4_9 | 1.41e-07 | 39 | 172 | 6 | 123 | Carbohydrate binding domain. This family includes diverse carbohydrate binding domains. |
| cd14256 | Dockerin_I | 1.19e-05 | 935 | 1002 | 2 | 57 | Type I dockerin repeat domain. Bacterial cohesin domains bind to a complementary protein domain named dockerin, and this interaction is required for the formation of the cellulosome, a cellulose-degrading complex. The cellulosome consists of scaffoldin, a noncatalytic scaffolding polypeptide, that comprises repeating cohesion modules and a single carbohydrate-binding module (CBM). Specific calcium-dependent interactions between cohesins and dockerins appear to be essential for cellulosome assembly. This subfamily represents type I dockerins, which are responsible for anchoring a variety of enzymatic domains to the complex. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| CBL17684.1 | 6.33e-246 | 1 | 980 | 2 | 932 |
| AAR01216.1 | 1.87e-222 | 3 | 963 | 2 | 944 |
| CAS03458.1 | 1.67e-221 | 1 | 963 | 1 | 948 |
| ADU22927.1 | 9.02e-219 | 3 | 963 | 6 | 941 |
| BAJ05815.1 | 3.96e-217 | 3 | 963 | 6 | 941 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 1UT9_A | 9.61e-123 | 244 | 916 | 7 | 604 | ChainA, CELLULOSE 1,4-BETA-CELLOBIOSIDASE [Acetivibrio thermocellus] |
| 1RQ5_A | 9.89e-123 | 244 | 922 | 7 | 610 | ChainA, Cellobiohydrolase [Acetivibrio thermocellus] |
| 3X17_A | 3.81e-54 | 244 | 914 | 18 | 554 | Crystalstructure of metagenome-derived glycoside hydrolase family 9 endoglucanase [uncultured bacterium],3X17_B Crystal structure of metagenome-derived glycoside hydrolase family 9 endoglucanase [uncultured bacterium] |
| 6DHT_A | 9.00e-48 | 244 | 916 | 18 | 564 | Bacteroidesovatus GH9 Bacova_02649 [Bacteroides ovatus ATCC 8483] |
| 4CJ0_A | 2.33e-39 | 266 | 951 | 36 | 576 | ChainA, ENDOGLUCANASE D [Acetivibrio thermocellus],4CJ1_A Chain A, ENDOGLUCANASE D [Acetivibrio thermocellus] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| A3DCH1 | 1.51e-135 | 36 | 955 | 42 | 853 | Cellulose 1,4-beta-cellobiosidase OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=celK PE=3 SV=1 |
| P0C2S1 | 1.51e-135 | 36 | 955 | 42 | 853 | Cellulose 1,4-beta-cellobiosidase OS=Acetivibrio thermocellus OX=1515 GN=celK PE=1 SV=1 |
| Q05156 | 2.59e-103 | 41 | 919 | 39 | 745 | Cellulase 1 OS=Streptomyces reticuli OX=1926 GN=cel1 PE=1 SV=1 |
| P14090 | 1.17e-95 | 244 | 921 | 341 | 912 | Endoglucanase C OS=Cellulomonas fimi (strain ATCC 484 / DSM 20113 / JCM 1341 / NBRC 15513 / NCIMB 8980 / NCTC 7547) OX=590998 GN=cenC PE=1 SV=2 |
| P10476 | 3.55e-92 | 246 | 921 | 39 | 603 | Endoglucanase A OS=Cellvibrio japonicus (strain Ueda107) OX=498211 GN=celA PE=3 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000371 | 0.998845 | 0.000167 | 0.000245 | 0.000174 | 0.000156 |
