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CAZyme Information: MGYG000004392_01541

You are here: Home > Sequence: MGYG000004392_01541

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Eubacterium_R sp900539325
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Acutalibacteraceae; Eubacterium_R; Eubacterium_R sp900539325
CAZyme ID MGYG000004392_01541
CAZy Family GH95
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
879 98697.88 4.5158
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004392 1828862 MAG Israel Asia
Gene Location Start: 57355;  End: 59994  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000004392_01541.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH95 51 865 5.3e-117 0.9847645429362881

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd20789 Cas13d 0.008 195 339 3 193
Class 2 type VI-D CRISPR-associated RNA-guided ribonuclease Cas13d. CRISPR-Cas (clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins) adaptive immune systems defend microbes against foreign nucleic acids via RNA-guided endonucleases. These systems are divided into two classes: class 1 systems utilize multiple Cas proteins and CRISPR RNA (crRNA) to form an effector complex while class 2 systems employ a large, single effector with crRNA to mediate interference. Class 2 type VI CRISPR-Cas13 systems use a single enzyme to target RNA using a programmable crRNA guide and are divided into four subtypes based on the identity of the Cas13 protein (Cas13a-d). The Cas13 proteins are capable of both, pre-crRNA processing and target RNA cleavage, which protect the host from phage attacks. Once bound to a target RNA, their non-specific RNase activity is activated. Cas13d enzymes are 20-30% smaller than other Cas13 subtypes, which enable flexible packaging into size-constrained therapeutic viral vectors such as adeno-associated virus.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
AUO19599.1 1.15e-242 44 879 7 830
QYR23103.1 4.34e-231 41 874 13 865
AIQ51360.1 2.64e-227 41 850 13 852
AIQ45759.1 1.01e-225 41 850 13 852
AFH60346.1 1.60e-223 41 861 13 861

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
4UFC_A 6.68e-20 346 858 281 741
Crystalstructure of the GH95 enzyme BACOVA_03438 [Bacteroides ovatus],4UFC_B Crystal structure of the GH95 enzyme BACOVA_03438 [Bacteroides ovatus]
2RDY_A 1.84e-13 346 858 281 752
ChainA, BH0842 protein [Halalkalibacterium halodurans C-125],2RDY_B Chain B, BH0842 protein [Halalkalibacterium halodurans C-125]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q8L7W8 7.88e-13 324 837 315 792
Alpha-L-fucosidase 2 OS=Arabidopsis thaliana OX=3702 GN=FUC95A PE=1 SV=1
A2R797 1.54e-11 153 838 137 757
Probable alpha-fucosidase A OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) OX=425011 GN=afcA PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as LIPO

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000000 0.000000 1.000068 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000004392_01541.