| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; TANB77; CAG-508; CAG-245; | |||||||||||
| CAZyme ID | MGYG000004449_00653 | |||||||||||
| CAZy Family | GT51 | |||||||||||
| CAZyme Description | Monofunctional biosynthetic peptidoglycan transglycosylase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 7432; End: 8160 Strand: - | |||||||||||
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT51 | 47 | 214 | 6.2e-58 | 0.9378531073446328 |
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam00912 | Transgly | 5.33e-69 | 58 | 215 | 21 | 177 | Transglycosylase. The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains. |
| COG0744 | MrcB | 8.18e-64 | 58 | 231 | 84 | 257 | Membrane carboxypeptidase (penicillin-binding protein) [Cell wall/membrane/envelope biogenesis]. |
| COG5009 | MrcA | 1.52e-59 | 58 | 236 | 75 | 253 | Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]. |
| PRK11636 | mrcA | 2.36e-40 | 64 | 224 | 80 | 239 | penicillin-binding protein 1a; Provisional |
| PRK13481 | PRK13481 | 4.74e-38 | 3 | 227 | 8 | 227 | glycosyltransferase; Provisional |
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| SET89048.1 | 2.49e-70 | 3 | 234 | 6 | 236 |
| QUO38940.1 | 1.33e-66 | 1 | 225 | 1 | 228 |
| QRP41835.1 | 1.67e-65 | 25 | 227 | 28 | 229 |
| ASN93505.1 | 1.67e-65 | 25 | 227 | 28 | 229 |
| ASB42272.1 | 1.95e-65 | 1 | 225 | 11 | 234 |
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 3NB6_A | 1.46e-39 | 52 | 227 | 22 | 196 | Crystalstructure of Aquifex aeolicus peptidoglycan glycosyltransferase in complex with Methylphosphoryl Neryl Moenomycin [Aquifex aeolicus] |
| 2OQO_A | 5.79e-39 | 52 | 227 | 22 | 196 | Crystalstructure of a peptidoglycan glycosyltransferase from a class A PBP: insight into bacterial cell wall synthesis [Aquifex aeolicus VF5],3D3H_A Crystal structure of a complex of the peptidoglycan glycosyltransferase domain from Aquifex aeolicus and neryl moenomycin A [Aquifex aeolicus],3NB7_A Crystal structure of Aquifex Aeolicus Peptidoglycan Glycosyltransferase in complex with Decarboxylated Neryl Moenomycin [Aquifex aeolicus] |
| 4OON_A | 1.50e-35 | 53 | 222 | 42 | 210 | Crystalstructure of PBP1a in complex with compound 17 ((4Z,8S,11E,14S)-5-(2-amino-1,3-thiazol-4-yl)-14-(5,6-dihydroxy-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-8-formyl-2-methyl-6-oxo-3,10-dioxa-4,7,11-triazatetradeca-4,11-diene-2,12,14-tricarboxylic acid) [Pseudomonas aeruginosa PAO1] |
| 5ZZK_A | 1.71e-32 | 41 | 233 | 48 | 245 | ChainA, Monofunctional glycosyltransferase [Staphylococcus aureus subsp. aureus Mu50] |
| 3HZS_A | 1.89e-32 | 41 | 233 | 12 | 209 | ChainA, Monofunctional glycosyltransferase [Staphylococcus aureus subsp. aureus MW2] |
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P40750 | 5.43e-42 | 25 | 239 | 54 | 267 | Penicillin-binding protein 4 OS=Bacillus subtilis (strain 168) OX=224308 GN=pbpD PE=1 SV=2 |
| O87579 | 7.79e-42 | 34 | 216 | 50 | 233 | Penicillin-binding protein 1A OS=Neisseria lactamica OX=486 GN=mrcA PE=3 SV=1 |
| P38050 | 6.97e-41 | 53 | 225 | 70 | 241 | Penicillin-binding protein 1F OS=Bacillus subtilis (strain 168) OX=224308 GN=pbpF PE=2 SV=2 |
| O05131 | 2.43e-40 | 52 | 216 | 70 | 233 | Penicillin-binding protein 1A OS=Neisseria gonorrhoeae OX=485 GN=mrcA PE=1 SV=3 |
| Q5FAC7 | 2.43e-40 | 52 | 216 | 70 | 233 | Penicillin-binding protein 1A OS=Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090) OX=242231 GN=mrcA PE=3 SV=3 |
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.785584 | 0.068997 | 0.142913 | 0.000330 | 0.000189 | 0.001994 |
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