logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000004456_00052

You are here: Home > Sequence: MGYG000004456_00052

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Prevotella sp900556795
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Prevotella; Prevotella sp900556795
CAZyme ID MGYG000004456_00052
CAZy Family GH137
CAZyme Description Beta-galactosidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1328 MGYG000004456_1|CGC4 150775.2 8.5631
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004456 3541309 MAG Israel Asia
Gene Location Start: 83279;  End: 87265  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.31 3.2.1.185

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH137 23 378 7.6e-142 0.9911764705882353
GH2 382 1012 7.9e-82 0.6728723404255319
CBM57 1003 1175 2.1e-41 0.9863945578231292

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG3250 LacZ 6.45e-39 457 797 101 407
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
pfam11721 Malectin 2.33e-31 1001 1168 1 146
Di-glucose binding within endoplasmic reticulum. Malectin is a membrane-anchored protein of the endoplasmic reticulum that recognizes and binds Glc2-N-glycan. It carries a signal peptide from residues 1-26, a C-terminal transmembrane helix from residues 255-274, and a highly conserved central part of approximately 190 residues followed by an acidic, glutamate-rich region. Carbohydrate-binding is mediated by the four aromatic residues, Y67, Y89, Y116, and F117 and the aspartate at D186. NMR-based ligand-screening studies has shown binding of the protein to maltose and related oligosaccharides, on the basis of which the protein has been designated "malectin", and its endogenous ligand is found to be Glc2-high-mannose N-glycan.
PRK10340 ebgA 3.55e-23 440 817 110 469
cryptic beta-D-galactosidase subunit alpha; Reviewed
PRK10150 PRK10150 1.80e-18 439 828 65 449
beta-D-glucuronidase; Provisional
PRK09525 lacZ 4.73e-16 490 797 173 463
beta-galactosidase.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QNT66957.1 0.0 2 1328 3 1329
BCS84862.1 0.0 30 1328 27 1273
QUR43084.1 0.0 5 1328 2 1399
SCV09658.1 0.0 5 1328 2 1399
QRQ56950.1 0.0 5 1328 2 1399

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5MUI_A 5.05e-180 5 384 8 380
Glycosidehydrolase BT_0996 [Bacteroides thetaiotaomicron VPI-5482]
5MT2_A 4.15e-174 5 384 8 380
Glycosidehydrolase BT_0996 [Bacteroides thetaiotaomicron VPI-5482],5MUJ_A BT0996 RGII Chain B Complex [Bacteroides thetaiotaomicron VPI-5482]
3CMG_A 1.82e-35 387 978 4 575
Crystalstructure of putative beta-galactosidase from Bacteroides fragilis [Bacteroides fragilis NCTC 9343]
5Z1A_A 2.03e-35 387 978 23 594
Thecrystal structure of Bacteroides fragilis beta-glucuronidase in complex with uronic isofagomine [Bacteroides fragilis NCTC 9343]
3FN9_A 1.25e-28 387 990 5 597
Crystalstructure of putative beta-galactosidase from bacteroides fragilis [Bacteroides fragilis NCTC 9343],3FN9_B Crystal structure of putative beta-galactosidase from bacteroides fragilis [Bacteroides fragilis NCTC 9343],3FN9_C Crystal structure of putative beta-galactosidase from bacteroides fragilis [Bacteroides fragilis NCTC 9343],3FN9_D Crystal structure of putative beta-galactosidase from bacteroides fragilis [Bacteroides fragilis NCTC 9343]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
T2KPJ7 4.69e-28 432 1000 96 658
Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_21970 PE=2 SV=1
T2KM09 1.23e-23 439 875 106 502
Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22050 PE=2 SV=2
A1SWB8 2.94e-19 490 797 170 461
Beta-galactosidase OS=Psychromonas ingrahamii (strain 37) OX=357804 GN=lacZ PE=3 SV=1
P77989 3.71e-19 387 820 3 412
Beta-galactosidase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=lacZ PE=3 SV=2
Q56307 3.98e-19 388 817 38 461
Beta-galactosidase OS=Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) OX=243274 GN=lacZ PE=1 SV=2

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.011828 0.985888 0.001022 0.000719 0.000282 0.000236

TMHMM  Annotations      download full data without filtering help

start end
7 26