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CAZyme Information: MGYG000004468_00110
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Alistipes_A sp900539755 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae; Alistipes_A; Alistipes_A sp900539755 | |||||||||||
| CAZyme ID | MGYG000004468_00110 | |||||||||||
| CAZy Family | GH97 | |||||||||||
| CAZyme Description | Glucan 1,4-alpha-glucosidase SusB | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 124013; End: 125932 Strand: + | |||||||||||
Full Sequence Download help
| MTSLSRLGLL CTGLLLGYVL PSAAQERIET HSPNGKLTIT VDMEQGAPNY EITYQDRPVV | 60 |
| LKSALGINGN GEWTHDMQIA EVTRSSCDTT WKPLYGERSE IPDQYNQSII RFTQTGHLSA | 120 |
| LQLEIRAYNE GIAFRYLFPE GGGYLHITDE ATEFTLPEGT MAYFAPLAQA EHQKLPLRNW | 180 |
| PGEADRPLTI ELPNGFYGAL CEAQVVDYVR TKFKLHESKA NTLACSMYGA VDEIAPYATP | 240 |
| WRVVMVAEKP GALIENNYLL LNLNPPCEID TPWWIKPGKV MREVTLSTQG AKKLVDFAVK | 300 |
| RNLQYIEFDA GWYGYEYEKA SDASKVDVDP RRNPNNDLDM EEVVRYANDR GIGVWVYVNQ | 360 |
| RALAAQLDTI LPLYHKWGIK GIKFGFVQVG SQMWTKWMHD AVKKCAEYQL MVDIHDEYRP | 420 |
| TGFSRTYPNL LTQEGVRGNE EMPDATNNLI LPFTRYVAGP ADYTISYYFR DFNGYNPQMI | 480 |
| DTLAPKARAI HATSGQQLAM TVVYYSPLQF LYWYDRPSDC QDEPELEFFD RVPTVWDDTK | 540 |
| VLQGEIGEYI TVARRKGNEW YVGCMNGVKP RSLDIPFDFL PTGQKYVAHI YRDGTVKTPT | 600 |
| RTKVEVETRT VDAKTVLPAK LYGSGGLAIW LEPIETTKR | 639 |
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH97 | 21 | 631 | 6.7e-179 | 0.9857369255150554 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam10566 | Glyco_hydro_97 | 1.41e-64 | 274 | 533 | 4 | 278 | Glycoside hydrolase 97. This domain is the catalytic region of the bacterial glycosyl-hydrolase family 97. This central part of the GH97 family protein sequences represents a typical and complete (beta/alpha)8-barrel or catalytic TIM-barrel type domain. The N- and C-terminal parts of the sequences, mainly consisting of beta-strands, form two additional non-catalytic domains. In all known glycosidases with the (beta-alpha)8-barrel fold, the amino acid residues at the active site are located on the C-termini of the beta-strands. |
| pfam14508 | GH97_N | 8.71e-62 | 32 | 255 | 1 | 225 | Glycosyl-hydrolase 97 N-terminal. This N-terminal domain of glycosyl-hydrolase-97 contributes part of the active site pocket. It is also important for contact with the catalytic and C-terminal domains of the whole. |
| pfam14509 | GH97_C | 1.27e-41 | 536 | 631 | 1 | 96 | Glycosyl-hydrolase 97 C-terminal, oligomerization. Glycosyl-hydrolase-97 is made up of three tightly linked and highly conserved globular domains. The C-terminal domain is found to be necessary for oligomerization of the whole molecule in order to create the active-site pocket and the Ca++-binding site. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| BCG54110.1 | 0.0 | 22 | 639 | 4 | 621 |
| QUT92205.1 | 2.88e-273 | 22 | 638 | 16 | 631 |
| ALJ62045.1 | 1.16e-272 | 22 | 638 | 16 | 631 |
| QJR57546.1 | 7.52e-269 | 13 | 633 | 8 | 628 |
| ALA75935.1 | 7.52e-269 | 13 | 633 | 8 | 628 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5HQ4_A | 1.34e-70 | 32 | 629 | 5 | 656 | AGlycoside Hydrolase Family 97 enzyme from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8],5HQA_A A Glycoside Hydrolase Family 97 enzyme in complex with Acarbose from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8] |
| 5HQC_A | 1.34e-70 | 32 | 629 | 5 | 656 | AGlycoside Hydrolase Family 97 enzyme R171K variant from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8] |
| 5HQB_A | 3.59e-70 | 32 | 629 | 5 | 656 | AGlycoside Hydrolase Family 97 enzyme (E480Q) in complex with Panose from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8] |
| 2D73_A | 5.48e-65 | 19 | 594 | 14 | 684 | CrystalStructure Analysis of SusB [Bacteroides thetaiotaomicron VPI-5482],2D73_B Crystal Structure Analysis of SusB [Bacteroides thetaiotaomicron VPI-5482],2ZQ0_A Crystal structure of SusB complexed with acarbose [Bacteroides thetaiotaomicron],2ZQ0_B Crystal structure of SusB complexed with acarbose [Bacteroides thetaiotaomicron] |
| 3WFA_A | 8.68e-65 | 32 | 594 | 7 | 664 | Catalyticrole of the calcium ion in GH97 inverting glycoside hydrolase [Bacteroides thetaiotaomicron],3WFA_B Catalytic role of the calcium ion in GH97 inverting glycoside hydrolase [Bacteroides thetaiotaomicron] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| G8JZS4 | 2.17e-64 | 24 | 594 | 21 | 684 | Glucan 1,4-alpha-glucosidase SusB OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=susB PE=1 SV=1 |
| Q8A6L0 | 3.77e-60 | 24 | 594 | 19 | 624 | Retaining alpha-galactosidase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_1871 PE=1 SV=1 |
| D7CFN7 | 1.81e-50 | 39 | 576 | 50 | 573 | Probable retaining alpha-galactosidase OS=Streptomyces bingchenggensis (strain BCW-1) OX=749414 GN=SBI_01652 PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000317 | 0.998987 | 0.000216 | 0.000170 | 0.000155 | 0.000148 |