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CAZyme Information: MGYG000004471_01448

You are here: Home > Sequence: MGYG000004471_01448

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species UBA1394 sp900554975
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; UBA1394; UBA1394 sp900554975
CAZyme ID MGYG000004471_01448
CAZy Family GH44
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
766 MGYG000004471_24|CGC2 84343.13 4.1436
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004471 1997651 MAG Israel Asia
Gene Location Start: 23321;  End: 25621  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.4 3.2.1.151

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH44 35 538 3.7e-150 0.9922178988326849
CBM76 545 692 1.1e-29 0.9503105590062112

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam12891 Glyco_hydro_44 1.10e-65 91 316 1 233
Glycoside hydrolase family 44. This is a family of bacterial glycoside hydrolases formerly known as cellulase family J, and now known as Cel44A. It is one of the major enzymatic components of the cellulosome of Clostridium thermocellum strain F1 and of many other Firmicutes.
cd14256 Dockerin_I 1.42e-10 710 763 1 56
Type I dockerin repeat domain. Bacterial cohesin domains bind to a complementary protein domain named dockerin, and this interaction is required for the formation of the cellulosome, a cellulose-degrading complex. The cellulosome consists of scaffoldin, a noncatalytic scaffolding polypeptide, that comprises repeating cohesion modules and a single carbohydrate-binding module (CBM). Specific calcium-dependent interactions between cohesins and dockerins appear to be essential for cellulosome assembly. This subfamily represents type I dockerins, which are responsible for anchoring a variety of enzymatic domains to the complex.
pfam00404 Dockerin_1 6.65e-08 711 763 1 55
Dockerin type I repeat. The dockerin repeat is the binding partner of the cohesin domain pfam00963. The cohesin-dockerin interaction is the crucial interaction for complex formation in the cellulosome. The dockerin repeats, each bearing homology to the EF-hand calcium-binding loop bind calcium.
cd14253 Dockerin 2.55e-04 711 761 1 53
Dockerin repeat domain. Dockerins are modules in the cellulosome complex that often anchor catalytic subunits by binding to cohesin domains of scaffolding proteins. Three types of dockerins and their corresponding cohesin have been described in the literature. This alignment models two consecutive dockerin repeats, the functional unit.
cd14254 Dockerin_II 0.004 711 757 1 47
Type II dockerin repeat domain. Bacterial cohesin domains bind to a complementary protein domain named dockerin, and this interaction is required for the formation of the cellulosome, a cellulose-degrading complex. The cellulosome consists of scaffoldin, a noncatalytic scaffolding polypeptide, that comprises repeating cohesion modules and a single carbohydrate-binding module (CBM). Specific calcium-dependent interactions between cohesins and dockerins appear to be essential for cellulosome assembly. This subfamily represents type II dockerins, which are responsible for mediating attachment of the cellulosome complex to the bacterial cell wall.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
ERJ96918.1 4.85e-293 4 692 14 709
CAC83072.1 3.82e-192 5 731 2 754
CDD54427.1 9.77e-191 5 733 2 714
CBL16808.1 2.47e-188 3 733 1 714
AAA95959.1 1.28e-183 5 599 2 593

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
3IK2_A 1.11e-131 36 537 2 509
CrystalStructure of a Glycoside Hydrolase Family 44 Endoglucanase produced by Clostridium acetobutylium ATCC 824 [Clostridium acetobutylicum ATCC 824]
2E0P_A 8.02e-129 37 537 10 514
ChainA, Endoglucanase [Acetivibrio thermocellus],2E4T_A Chain A, Endoglucanase [Acetivibrio thermocellus],2EO7_A Chain A, Endoglucanase [Acetivibrio thermocellus]
2EEX_A 2.24e-128 37 537 10 514
ChainA, Endoglucanase [Acetivibrio thermocellus],2EJ1_A Chain A, Endoglucanase [Acetivibrio thermocellus],2EQD_A Chain A, Endoglucanase [Acetivibrio thermocellus]
2YIH_A 2.01e-116 37 538 10 516
Structureof a Paenibacillus polymyxa Xyloglucanase from GH family 44 with Xyloglucan [Paenibacillus polymyxa],2YJQ_A Structure of a Paenibacillus Polymyxa Xyloglucanase from Glycoside Hydrolase Family 44 [Paenibacillus polymyxa],2YJQ_B Structure of a Paenibacillus Polymyxa Xyloglucanase from Glycoside Hydrolase Family 44 [Paenibacillus polymyxa]
2YKK_A 3.35e-114 37 538 10 516
Structureof a Paenibacillus Polymyxa Xyloglucanase from Glycoside Hydrolase Family 44 [Paenibacillus polymyxa],3ZQ9_A Structure of a Paenibacillus Polymyxa Xyloglucanase from Glycoside Hydrolase Family 44 [Paenibacillus polymyxa]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P29719 2.25e-118 10 543 10 547
Endoglucanase A OS=Paenibacillus lautus OX=1401 GN=celA PE=3 SV=1
P22533 9.55e-102 37 539 788 1305
Beta-mannanase/endoglucanase A OS=Caldicellulosiruptor saccharolyticus OX=44001 GN=manA PE=1 SV=2

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000821 0.910564 0.087695 0.000317 0.000311 0.000256

TMHMM  Annotations      download full data without filtering help

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