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CAZyme Information: MGYG000004517_01302

You are here: Home > Sequence: MGYG000004517_01302

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; UBA5884;
CAZyme ID MGYG000004517_01302
CAZy Family GH48
CAZyme Description Cellulose 1,4-beta-cellobiosidase (reducing end) CelS
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
958 MGYG000004517_31|CGC1 105212.39 4.2021
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004517 2174745 MAG Israel Asia
Gene Location Start: 2448;  End: 5324  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.-

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH48 61 766 7.4e-200 0.9967266775777414

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam02011 Glyco_hydro_48 0.0 61 768 1 620
Glycosyl hydrolase family 48. Members of this family are endoglucanase EC:3.2.1.4 and exoglucanase EC:3.2.1.91 enzymes that cleave cellulose or related substrate.
cd14256 Dockerin_I 1.26e-09 887 937 2 48
Type I dockerin repeat domain. Bacterial cohesin domains bind to a complementary protein domain named dockerin, and this interaction is required for the formation of the cellulosome, a cellulose-degrading complex. The cellulosome consists of scaffoldin, a noncatalytic scaffolding polypeptide, that comprises repeating cohesion modules and a single carbohydrate-binding module (CBM). Specific calcium-dependent interactions between cohesins and dockerins appear to be essential for cellulosome assembly. This subfamily represents type I dockerins, which are responsible for anchoring a variety of enzymatic domains to the complex.
pfam02368 Big_2 5.22e-09 785 844 3 69
Bacterial Ig-like domain (group 2). This family consists of bacterial domains with an Ig-like fold. Members of this family are found in bacterial and phage surface proteins such as intimins.
pfam00404 Dockerin_1 7.00e-07 887 937 1 47
Dockerin type I repeat. The dockerin repeat is the binding partner of the cohesin domain pfam00963. The cohesin-dockerin interaction is the crucial interaction for complex formation in the cellulosome. The dockerin repeats, each bearing homology to the EF-hand calcium-binding loop bind calcium.
pfam13629 T2SS-T3SS_pil_N 5.68e-05 790 844 3 61
Pilus formation protein N terminal region.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
CBL17316.1 1.88e-279 5 773 4 722
AAR01217.1 3.86e-259 7 786 5 789
CAS03459.1 6.25e-257 7 778 10 787
ADU23081.1 3.97e-256 3 777 2 788
BAJ05814.1 3.97e-256 3 777 2 788

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
1L1Y_A 1.16e-177 46 772 25 665
ChainA, cellobiohydrolase [Acetivibrio thermocellus],1L1Y_B Chain B, cellobiohydrolase [Acetivibrio thermocellus],1L1Y_C Chain C, cellobiohydrolase [Acetivibrio thermocellus],1L1Y_D Chain D, cellobiohydrolase [Acetivibrio thermocellus],1L1Y_E Chain E, cellobiohydrolase [Acetivibrio thermocellus],1L1Y_F Chain F, cellobiohydrolase [Acetivibrio thermocellus],1L2A_A Chain A, cellobiohydrolase [Acetivibrio thermocellus],1L2A_B Chain B, cellobiohydrolase [Acetivibrio thermocellus],1L2A_C Chain C, cellobiohydrolase [Acetivibrio thermocellus],1L2A_D Chain D, cellobiohydrolase [Acetivibrio thermocellus],1L2A_E Chain E, cellobiohydrolase [Acetivibrio thermocellus],1L2A_F Chain F, cellobiohydrolase [Acetivibrio thermocellus]
5YJ6_A 6.12e-177 51 770 3 636
ChainA, Dockerin type I repeat-containing protein [Acetivibrio thermocellus DSM 1313]
4XWL_A 1.57e-175 41 773 27 676
Catalyticdomain of Clostridium Cellulovorans Exgs [Clostridium cellulovorans],4XWM_A Complex structure of catalytic domain of Clostridium Cellulovorans Exgs and Cellobiose [Clostridium cellulovorans],4XWN_A Complex structure of catalytic domain of Clostridium Cellulovorans Exgs and Cellotetraose [Clostridium cellulovorans]
6D5D_A 3.25e-170 55 770 14 644
Structureof Caldicellulosiruptor danielii GH48 module of glycoside hydrolase WP_045175321 [Caldicellulosiruptor danielii]
4EL8_A 9.57e-166 61 770 9 633
Theunliganded structure of C.bescii CelA GH48 module [Caldicellulosiruptor bescii DSM 6725]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
A3DH67 4.64e-176 46 772 25 665
Cellulose 1,4-beta-cellobiosidase (reducing end) CelS OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=celS PE=1 SV=1
P0C2S5 4.64e-176 46 772 25 665
Cellulose 1,4-beta-cellobiosidase (reducing end) CelS OS=Acetivibrio thermocellus OX=1515 GN=celS PE=1 SV=1
P50900 1.03e-162 58 768 37 655
Exoglucanase-2 OS=Thermoclostridium stercorarium (strain ATCC 35414 / DSM 8532 / NCIMB 11754) OX=1121335 GN=celY PE=1 SV=2
P37698 1.43e-157 53 774 30 662
Endoglucanase F OS=Ruminiclostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10) OX=394503 GN=celCCF PE=1 SV=2
P22534 1.27e-155 61 770 1117 1741
Endoglucanase A OS=Caldicellulosiruptor saccharolyticus OX=44001 GN=celA PE=3 SV=2

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.001701 0.996804 0.000335 0.000449 0.000359 0.000318

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000004517_01302.