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CAZyme Information: MGYG000004519_00951

You are here: Home > Sequence: MGYG000004519_00951

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; TWA4;
CAZyme ID MGYG000004519_00951
CAZy Family GH18
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
571 65167.32 6.3958
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004519 2064379 MAG Israel Asia
Gene Location Start: 6565;  End: 8280  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000004519_00951.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH18 279 559 1.2e-38 0.8445945945945946

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd02874 GH18_CFLE_spore_hydrolase 3.39e-71 260 565 17 313
Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in bacterial endospore germination. CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells. SleB translocates across the forespore inner membrane and is deposited as a mature enzyme in the cortex layer of the spore. As part of a sensory mechanism capable of initiating germination, CFLE degrades a spore-specific peptidoglycan constituent called muramic-acid delta-lactam that comprises the outer cortex. CFLE has a C-terminal glycosyl hydrolase family 18 (GH18) catalytic domain as well as two N-terminal LysM peptidoglycan-binding domains. In addition to SleB, this family includes YaaH, YdhD, and YvbX from Bacillus subtilis.
COG3858 YaaH 8.49e-46 260 565 118 418
Spore germination protein YaaH [Cell cycle control, cell division, chromosome partitioning].
smart00636 Glyco_18 4.42e-28 265 556 22 333
Glyco_18 domain.
pfam00704 Glyco_hydro_18 3.69e-27 279 555 40 305
Glycosyl hydrolases family 18.
cd06549 GH18_trifunctional 7.44e-22 260 562 15 298
GH18 domain of an uncharacterized family of bacterial proteins, which share a common three-domain architecture: an N-terminal glycosyl hydrolase family 18 (GH18) domain, a glycosyl transferase family 2 domain, and a C-terminal polysaccharide deacetylase domain.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QRT51337.1 4.37e-133 6 568 49 617
AWY97382.1 3.21e-131 16 570 27 567
BBF44731.1 4.92e-130 8 568 16 564
SEU04925.1 1.04e-128 30 565 28 548
CBL13521.1 4.12e-128 8 568 14 608

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
3CZ8_A 1.17e-20 318 556 86 310
ChainA, Putative sporulation-specific glycosylase ydhD [Bacillus subtilis subsp. subtilis str. 168],3CZ8_B Chain B, Putative sporulation-specific glycosylase ydhD [Bacillus subtilis subsp. subtilis str. 168]
4S3J_A 7.53e-20 321 567 189 423
Crystalstructure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876],4S3J_B Crystal structure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876],4S3J_C Crystal structure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876]
4S3K_A 5.96e-17 321 565 190 423
ChainA, Spore germination protein YaaH [Priestia megaterium QM B1551]
5JH8_A 3.08e-15 324 565 85 310
Crystalstructure of chitinase from Chromobacterium violaceum ATCC 12472 [Chromobacterium violaceum ATCC 12472]
4Q6T_A 8.04e-14 263 565 34 335
Thecrystal structure of a class V chitininase from Pseudomonas fluorescens Pf-5 [Pseudomonas protegens Pf-5]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
O05495 2.67e-20 318 556 178 402
Putative sporulation-specific glycosylase YdhD OS=Bacillus subtilis (strain 168) OX=224308 GN=ydhD PE=1 SV=2
P0DPJ9 2.30e-18 321 567 188 422
Cortical fragment-lytic enzyme OS=Bacillus anthracis OX=1392 GN=sleL PE=2 SV=1
P37531 3.10e-18 321 566 186 420
Cortical fragment-lytic enzyme OS=Bacillus subtilis (strain 168) OX=224308 GN=sleL PE=1 SV=2
Q9K3E4 9.82e-18 321 567 188 422
Cortical fragment-lytic enzyme OS=Bacillus cereus OX=1396 GN=sleL PE=1 SV=1
O31682 4.26e-16 245 458 11 214
Putative glycosylase YkvQ OS=Bacillus subtilis (strain 168) OX=224308 GN=ykvQ PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.924535 0.050035 0.022239 0.000226 0.000131 0.002844

TMHMM  Annotations      download full data without filtering help

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