CAZyme Information: MGYG000004587_02295

Basic Information

• Species: UBA1409 sp900553675
• Lineage: Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; UBA1409; UBA1409 sp900553675
• CAZyme ID: MGYG000004587_02295
• CAZy Family: GH2
• CAZyme Description: Beta-galactosidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1116	MGYG000004587_39|CGC1	126243.12	4.9627

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000004587	2560840	MAG	France	Europe

• Gene Location: Start: 1378; End: 4728 Strand: +

Full Sequence      

MYRLFNDNWQFCLKHIGKKPADSDYKPVNIPHDWQIYNTLDLYSTRDGFYRKRFSVTAPE
KSVYTLRFEGVYMDCEIYLNGEKIFEWKYGYTTFDVPLSGLRDGENELIVRVRYQSPNSR
WYSGAGIYRNVWLRETGESYILADGTYVVSYPAGDVWRTEIDTEINAIASGSVRHILLDS
DGKSVASSEAGFEAGAVKVSQSFEIAQPHLWGVDDPYLYTLRTELIINGEIADVRQERIG
YRTIRFDSAEGFFLNGENLKLNGACMHHDLGALGSAVNRAATRRQLAILKDMGVNSIRTS
HNPPSVEFMELCDEMGILVDSEGFDMWELKKNDYDYHRFFPEWHERDTRSWVRRDRNHPS
VIMWSIGNEIYDTHASPRGAEITKELARCVRIDDYKNAHPVTIGSNYMRWEPAQKCAKYL
DVIGYNYTEDAYDEHHQKHPKWIIYGSETASTVQSRGVYHFPARVFTTNYDDGQCSSLLN
CATGWGAPGPEYNITMDRDRKYSLGQFIWTGFDYIGEPTPYHSKNSFFGHIDTAGFPKDT
FYAYKAEWNKNAEPFVHLFPYWDFNEGQLVDIFAFSNCAKTELFVNGESVGCFEHNHESG
KELTGRWQVPYHKGYIKAVGYNENGVKLCEQIRASFGDPAKIVLRPDKTTLSADGEDMAF
VEVSAADKDGNTVENARNRINVEISGAGRLLGLDNGDSTDYEQYKTTSRRLYSGKLLIMI
GSKKDAGDIRIRVSSPELSDEVLKLEAAPAQAREGVSCIDDDIRTEKKRDVSLRKIELSV
SDQLITPENKTASVSIKLLPENTSFTADDVAFKAVTDSGVETNLLEIEKDGLNAVLKPRG
DGVYRLRAYCKNGTSVEEIISETEMENRGFGPASFDPYSAIICASVASNAGELTSNMEGG
VLTEYGDTKVRFDCVDFGNTGSDEITIGIYTYNEGKIPVDLYVDGEHIQTLMFQAKNEWN
VYKYNTFRLSEKLKGVHNLEFMLHEQLRFKGFKFLSPRRLGEEISALENDGIYGDSFSIG
SEMIEHIGNNVTVSFGGIDLLGGANAVEITGRTHNQHDTLHLRFTSGEMSAVEFESSDGI
VTRRFDIDTIDGVKDLQLVFLPCSDFDLKSLRFIRI

Enzyme Prediction     

EC	3.2.1.8	3.1.1.73

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH2	3	546	1.1e-109	0.6037234042553191

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG3250	LacZ	1.50e-70	5	523	30	566	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10150	PRK10150	8.17e-52	66	426	86	470	beta-D-glucuronidase; Provisional
PRK10340	ebgA	7.31e-42	2	399	41	473	cryptic beta-D-galactosidase subunit alpha; Reviewed
pfam18565	Glyco_hydro2_C5	2.09e-38	642	744	1	103	Glycoside hydrolase family 2 C-terminal domain 5. Domain 5 is found in dimeric beta-D-galactosidase from Paracoccus sp. 32d, which contributes to stabilization of the functional dimer. It is suggested that the location of this domain 5, may be one of the factors responsible for the creation of a functional dimer and cold-adaptation of this enzyme.
PRK09525	lacZ	6.46e-27	3	369	53	462	beta-galactosidase.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
BCJ94036.1	0.0	1	1113	4	1145
BCJ98579.1	0.0	1	1113	1	1135
CQR57247.1	0.0	3	1114	5	1155
AWP27978.1	0.0	4	1116	6	1153
AVV58790.1	0.0	4	1116	6	1153

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7CWD_A	1.19e-189	5	739	6	793	ChainA, beta-glalactosidase [Niallia circulans],7CWI_A Chain A, beta-galactosidase [Niallia circulans]
4YPJ_A	2.10e-181	5	741	12	801	ChainA, Beta galactosidase [Niallia circulans],4YPJ_B Chain B, Beta galactosidase [Niallia circulans]
5T98_A	1.12e-159	5	738	30	811	Crystalstructure of BuGH2Awt [Bacteroides uniformis],5T98_B Crystal structure of BuGH2Awt [Bacteroides uniformis],5T99_A Crystal structure of BuGH2Awt in complex with Galactoisofagomine [Bacteroides uniformis],5T99_B Crystal structure of BuGH2Awt in complex with Galactoisofagomine [Bacteroides uniformis]
4CU6_A	5.28e-146	5	735	18	832	Unravellingthe multiple functions of the architecturally intricate Streptococcus pneumoniae beta-galactosidase, BgaA [Streptococcus pneumoniae TIGR4],4CU7_A Unravelling the multiple functions of the architecturally intricate Streptococcus pneumoniae beta-galactosidase, BgaA [Streptococcus pneumoniae TIGR4],4CU8_A Unravelling the multiple functions of the architecturally intricate Streptococcus pneumoniae beta-galactosidase, BgaA [Streptococcus pneumoniae TIGR4]
4CUC_A	1.45e-145	5	735	18	832	Unravellingthe multiple functions of the architecturally intricate Streptococcus pneumoniae beta-galactosidase, BgaA. [Streptococcus pneumoniae TIGR4]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
A7LXS9	1.39e-163	5	747	47	848	Beta-galactosidase BoGH2A OS=Bacteroides ovatus (strain ATCC 8483 / DSM 1896 / JCM 5824 / BCRC 10623 / CCUG 4943 / NCTC 11153) OX=411476 GN=BACOVA_02645 PE=1 SV=1
T2KM09	1.51e-88	5	959	51	996	Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22050 PE=2 SV=2
T2KPJ7	1.09e-55	6	636	57	720	Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_21970 PE=2 SV=1
P77989	2.40e-49	5	741	8	731	Beta-galactosidase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=lacZ PE=3 SV=2
P26257	1.16e-40	6	692	8	706	Beta-galactosidase OS=Thermoanaerobacterium thermosulfurigenes OX=33950 GN=lacZ PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000054	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000004587_02295.