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CAZyme Information: MGYG000004622_01085
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Prevotella sp900316565 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Prevotella; Prevotella sp900316565 | |||||||||||
| CAZyme ID | MGYG000004622_01085 | |||||||||||
| CAZy Family | GT2 | |||||||||||
| CAZyme Description | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 14478; End: 15746 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT2 | 7 | 128 | 8e-23 | 0.7294117647058823 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd06433 | GT_2_WfgS_like | 2.65e-62 | 7 | 207 | 1 | 201 | WfgS and WfeV are involved in O-antigen biosynthesis. Escherichia coli WfgS and Shigella dysenteriae WfeV are glycosyltransferase 2 family enzymes involved in O-antigen biosynthesis. GT-2 enzymes have GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families. |
| cd04647 | LbH_MAT_like | 5.45e-37 | 300 | 402 | 1 | 107 | Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form. |
| cd03357 | LbH_MAT_GAT | 2.22e-25 | 272 | 402 | 34 | 167 | Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). |
| PRK10502 | PRK10502 | 2.32e-25 | 257 | 407 | 25 | 178 | putative acyl transferase; Provisional |
| cd03349 | LbH_XAT | 5.26e-25 | 300 | 407 | 1 | 127 | Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. Members of this class of enzymes include Enterococcus faecium streptogramin A acetyltransferase and Pseudomonas aeruginosa chloramphenicol acetyltransferase. They contain repeated copies of a six-residue hexapeptide repeat sequence motif (X-[STAV]-X-[LIV]-[GAED]-X) and adopt a left-handed parallel beta helix (LbH) structure. The active enzyme is a trimer with CoA and substrate binding sites at the interface of two separate LbH subunits. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AXV50072.1 | 2.53e-153 | 5 | 420 | 4 | 419 |
| QUI93290.1 | 2.53e-153 | 5 | 420 | 4 | 419 |
| QUB91771.1 | 2.06e-152 | 5 | 420 | 4 | 419 |
| QJR60740.1 | 9.36e-66 | 4 | 223 | 3 | 222 |
| QJR54460.1 | 9.36e-66 | 4 | 223 | 3 | 222 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5HEA_A | 8.66e-09 | 2 | 118 | 3 | 120 | CgTstructure in hexamer [Streptococcus parasanguinis FW213],5HEA_B CgT structure in hexamer [Streptococcus parasanguinis FW213],5HEA_C CgT structure in hexamer [Streptococcus parasanguinis FW213],5HEC_A CgT structure in dimer [Streptococcus parasanguinis FW213],5HEC_B CgT structure in dimer [Streptococcus parasanguinis FW213] |
| 4H7O_A | 3.35e-08 | 300 | 405 | 141 | 245 | Crystalstructure of Serine acetyltransferase from Vibrio cholerae O1 biovar El Tor N16961 [Vibrio cholerae O1 biovar El Tor str. N16961],4H7O_B Crystal structure of Serine acetyltransferase from Vibrio cholerae O1 biovar El Tor N16961 [Vibrio cholerae O1 biovar El Tor str. N16961],4H7O_C Crystal structure of Serine acetyltransferase from Vibrio cholerae O1 biovar El Tor N16961 [Vibrio cholerae O1 biovar El Tor str. N16961] |
| 6JVU_A | 4.49e-08 | 300 | 405 | 149 | 253 | ChainA, Serine acetyltransferase [Klebsiella pneumoniae MGH 78578],6JVU_B Chain B, Serine acetyltransferase [Klebsiella pneumoniae MGH 78578],6JVU_C Chain C, Serine acetyltransferase [Klebsiella pneumoniae MGH 78578],6JVU_D Chain D, Serine acetyltransferase [Klebsiella pneumoniae MGH 78578],6JVU_E Chain E, Serine acetyltransferase [Klebsiella pneumoniae MGH 78578],6JVU_F Chain F, Serine acetyltransferase [Klebsiella pneumoniae MGH 78578] |
| 7E3Y_A | 4.49e-08 | 300 | 405 | 149 | 253 | ChainA, Serine acetyltransferase [Salmonella enterica subsp. enterica serovar Typhimurium],7E3Y_B Chain B, Serine acetyltransferase [Salmonella enterica subsp. enterica serovar Typhimurium],7E3Y_C Chain C, Serine acetyltransferase [Salmonella enterica subsp. enterica serovar Typhimurium] |
| 1KQA_A | 4.98e-08 | 272 | 404 | 47 | 182 | GalactosideAcetyltransferase In Complex With Coenzyme A [Escherichia coli],1KQA_B Galactoside Acetyltransferase In Complex With Coenzyme A [Escherichia coli],1KQA_C Galactoside Acetyltransferase In Complex With Coenzyme A [Escherichia coli],1KRR_A Galactoside Acetyltransferase in Complex with Acetyl-Coenzyme A [Escherichia coli],1KRR_B Galactoside Acetyltransferase in Complex with Acetyl-Coenzyme A [Escherichia coli],1KRR_C Galactoside Acetyltransferase in Complex with Acetyl-Coenzyme A [Escherichia coli],1KRU_A Galactoside Acetyltransferase in Complex with IPTG and Coenzyme A [Escherichia coli],1KRU_B Galactoside Acetyltransferase in Complex with IPTG and Coenzyme A [Escherichia coli],1KRU_C Galactoside Acetyltransferase in Complex with IPTG and Coenzyme A [Escherichia coli],1KRV_A Galactoside Acetyltransferase in Complex with CoA and PNP-beta-Gal [Escherichia coli],1KRV_B Galactoside Acetyltransferase in Complex with CoA and PNP-beta-Gal [Escherichia coli],1KRV_C Galactoside Acetyltransferase in Complex with CoA and PNP-beta-Gal [Escherichia coli] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P9WMX9 | 1.14e-18 | 2 | 181 | 3 | 183 | Uncharacterized glycosyltransferase Rv1514c OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=Rv1514c PE=1 SV=1 |
| P9WMX8 | 1.14e-18 | 2 | 181 | 3 | 183 | Uncharacterized glycosyltransferase MT1564 OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=MT1564 PE=3 SV=1 |
| P71239 | 1.72e-14 | 6 | 205 | 3 | 201 | Putative colanic acid biosynthesis glycosyl transferase WcaE OS=Escherichia coli (strain K12) OX=83333 GN=wcaE PE=4 SV=2 |
| P9WMX6 | 2.19e-13 | 1 | 120 | 1 | 124 | PGL/p-HBAD biosynthesis glycosyltransferase MT3031 OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=MT3031 PE=3 SV=1 |
| P9WMX7 | 2.19e-13 | 1 | 120 | 1 | 124 | PGL/p-HBAD biosynthesis glycosyltransferase Rv2957 OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=Rv2957 PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000051 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |