Species | CAG-521 sp900553105 | |||||||||||
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Lineage | Bacteria; Proteobacteria; Gammaproteobacteria; Burkholderiales; Burkholderiaceae; CAG-521; CAG-521 sp900553105 | |||||||||||
CAZyme ID | MGYG000004626_01222 | |||||||||||
CAZy Family | GT9 | |||||||||||
CAZyme Description | Lipopolysaccharide heptosyltransferase 1 | |||||||||||
CAZyme Property |
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Genome Property |
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Gene Location | Start: 71451; End: 72401 Strand: - |
Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
---|---|---|---|---|---|---|---|
TIGR02193 | heptsyl_trn_I | 9.57e-126 | 4 | 316 | 1 | 319 | lipopolysaccharide heptosyltransferase I. This family consists of examples of ADP-heptose:LPS heptosyltransferase I, an enzyme of LPS inner core region biosynthesis. LPS, composed of lipid A, a core region, and O antigen, is found in the outer membrane of Gram-negative bacteria. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides] |
PRK10964 | PRK10964 | 1.38e-98 | 4 | 316 | 2 | 320 | lipopolysaccharide heptosyltransferase RfaC. |
COG0859 | RfaF | 2.29e-67 | 3 | 278 | 2 | 277 | ADP-heptose:LPS heptosyltransferase [Cell wall/membrane/envelope biogenesis]. |
pfam01075 | Glyco_transf_9 | 4.34e-50 | 79 | 278 | 3 | 209 | Glycosyltransferase family 9 (heptosyltransferase). Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core. |
cd03789 | GT9_LPS_heptosyltransferase | 6.07e-43 | 4 | 278 | 1 | 222 | lipopolysaccharide heptosyltransferase and similar proteins. Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
---|---|---|---|---|---|
ANU66485.1 | 3.17e-93 | 5 | 316 | 3 | 314 |
QQQ97633.1 | 3.17e-93 | 5 | 316 | 3 | 314 |
AKR42527.1 | 1.07e-84 | 3 | 315 | 11 | 321 |
ABE49021.1 | 6.91e-84 | 4 | 315 | 6 | 321 |
ASJ22846.1 | 6.51e-83 | 4 | 316 | 3 | 317 |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
2GT1_A | 4.80e-69 | 4 | 310 | 2 | 311 | E.coli heptosyltransferase WaaC. [Escherichia coli UTI89],2GT1_B E. coli heptosyltransferase WaaC. [Escherichia coli UTI89] |
6DFE_A | 4.80e-69 | 4 | 310 | 2 | 311 | Thestructure of a ternary complex of E. coli WaaC [Escherichia coli],6DFE_B The structure of a ternary complex of E. coli WaaC [Escherichia coli] |
2H1F_A | 6.05e-69 | 4 | 310 | 2 | 311 | E.coli heptosyltransferase WaaC with ADP [Escherichia coli O6],2H1F_B E. coli heptosyltransferase WaaC with ADP [Escherichia coli O6],2H1H_A E. coli heptosyltransferase WaaC with ADP-2-deoxy-2-fluoro heptose [Escherichia coli RS218],2H1H_B E. coli heptosyltransferase WaaC with ADP-2-deoxy-2-fluoro heptose [Escherichia coli RS218] |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
P26469 | 2.85e-68 | 4 | 291 | 2 | 292 | Lipopolysaccharide heptosyltransferase 1 OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=rfaC PE=3 SV=2 |
P24173 | 3.39e-67 | 4 | 291 | 2 | 292 | Lipopolysaccharide heptosyltransferase 1 OS=Escherichia coli (strain K12) OX=83333 GN=rfaC PE=1 SV=1 |
Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
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1.000078 | 0.000002 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |
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