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CAZyme Information: MGYG000004634_00368
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Lachnospirales; CAG-274; UMGS1441; | |||||||||||
| CAZyme ID | MGYG000004634_00368 | |||||||||||
| CAZy Family | GH18 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 10151; End: 11707 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH18 | 189 | 507 | 7.2e-28 | 0.9222972972972973 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd02874 | GH18_CFLE_spore_hydrolase | 3.12e-33 | 234 | 514 | 43 | 313 | Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in bacterial endospore germination. CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells. SleB translocates across the forespore inner membrane and is deposited as a mature enzyme in the cortex layer of the spore. As part of a sensory mechanism capable of initiating germination, CFLE degrades a spore-specific peptidoglycan constituent called muramic-acid delta-lactam that comprises the outer cortex. CFLE has a C-terminal glycosyl hydrolase family 18 (GH18) catalytic domain as well as two N-terminal LysM peptidoglycan-binding domains. In addition to SleB, this family includes YaaH, YdhD, and YvbX from Bacillus subtilis. |
| COG3858 | YaaH | 3.94e-25 | 211 | 516 | 134 | 420 | Spore germination protein YaaH [Cell cycle control, cell division, chromosome partitioning]. |
| NF033190 | inl_like_NEAT_1 | 6.01e-17 | 16 | 172 | 576 | 748 | NEAT domain-containing leucine-rich repeat protein. Members of this family have an N-terminal NEAT (near transporter) domain often associated with iron transport, followed by a leucine-rich repeat region with significant sequence similarity to the internalins of Listeria monocytogenes. However, since Bacillus cereus (from which this protein was described, in PMID:16978259) is not considered an intracellular pathogen, and the function may be iron transport rather than internalization, applying the name "internalin" to this family probably would be misleading. |
| pfam00704 | Glyco_hydro_18 | 9.58e-14 | 273 | 505 | 81 | 306 | Glycosyl hydrolases family 18. |
| cd06549 | GH18_trifunctional | 9.14e-11 | 231 | 511 | 25 | 298 | GH18 domain of an uncharacterized family of bacterial proteins, which share a common three-domain architecture: an N-terminal glycosyl hydrolase family 18 (GH18) domain, a glycosyl transferase family 2 domain, and a C-terminal polysaccharide deacetylase domain. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AOY78038.1 | 2.98e-126 | 22 | 514 | 32 | 574 |
| ARE88674.1 | 2.98e-126 | 22 | 514 | 32 | 574 |
| QOX64072.1 | 5.34e-123 | 22 | 508 | 30 | 549 |
| ANW99040.1 | 2.28e-122 | 18 | 514 | 28 | 572 |
| ANX01568.1 | 2.28e-122 | 18 | 514 | 28 | 572 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 4S3K_A | 1.02e-10 | 254 | 517 | 171 | 426 | ChainA, Spore germination protein YaaH [Priestia megaterium QM B1551] |
| 4WIW_A | 1.17e-06 | 272 | 509 | 103 | 335 | ChainA, Glycoside hydrolase family 18 [Desulfitobacterium hafniense DCB-2],4WIW_B Chain B, Glycoside hydrolase family 18 [Desulfitobacterium hafniense DCB-2],4WIW_C Chain C, Glycoside hydrolase family 18 [Desulfitobacterium hafniense DCB-2],4WIW_D Chain D, Glycoside hydrolase family 18 [Desulfitobacterium hafniense DCB-2],4WIW_E Chain E, Glycoside hydrolase family 18 [Desulfitobacterium hafniense DCB-2],4WIW_F Chain F, Glycoside hydrolase family 18 [Desulfitobacterium hafniense DCB-2] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P38535 | 7.36e-13 | 22 | 180 | 908 | 1085 | Exoglucanase XynX OS=Acetivibrio thermocellus OX=1515 GN=xynX PE=3 SV=1 |
| P38536 | 5.88e-12 | 22 | 172 | 1682 | 1851 | Amylopullulanase OS=Thermoanaerobacterium thermosulfurigenes OX=33950 GN=amyB PE=3 SV=2 |
| P19424 | 7.85e-11 | 1 | 172 | 20 | 210 | Endoglucanase OS=Bacillus sp. (strain KSM-635) OX=1415 PE=1 SV=1 |
| O32258 | 1.57e-09 | 216 | 516 | 51 | 341 | Uncharacterized glycosylase YvbX OS=Bacillus subtilis (strain 168) OX=224308 GN=yvbX PE=3 SV=1 |
| P22258 | 5.10e-07 | 22 | 120 | 96 | 190 | Cell surface protein OS=Thermoanaerobacter kivui OX=2325 PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000823 | 0.998218 | 0.000229 | 0.000255 | 0.000236 | 0.000216 |