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CAZyme Information: MGYG000004645_00124
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; QALW01; UMGS1322; | |||||||||||
| CAZyme ID | MGYG000004645_00124 | |||||||||||
| CAZy Family | GT39 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 38768; End: 43600 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT39 | 1152 | 1383 | 7.1e-49 | 0.9237668161434978 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam16192 | PMT_4TMC | 1.64e-19 | 1401 | 1604 | 7 | 198 | C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes. |
| COG1928 | PMT1 | 2.87e-16 | 1401 | 1608 | 505 | 695 | Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]. |
| COG1928 | PMT1 | 1.63e-12 | 1154 | 1321 | 46 | 227 | Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]. |
| pfam02366 | PMT | 4.44e-12 | 1151 | 1321 | 16 | 200 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
| COG5542 | COG5542 | 6.91e-12 | 259 | 608 | 50 | 370 | Mannosyltransferase related to Gpi18 [Carbohydrate transport and metabolism]. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| CQR52353.1 | 2.32e-173 | 29 | 1608 | 30 | 1275 |
| QUL55595.1 | 3.46e-173 | 29 | 1608 | 30 | 1278 |
| AIQ39188.1 | 3.54e-173 | 29 | 1608 | 30 | 1279 |
| AIQ56104.1 | 1.32e-171 | 29 | 1608 | 30 | 1279 |
| AIQ27397.1 | 1.84e-171 | 29 | 1608 | 30 | 1279 |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P9WN04 | 1.96e-12 | 1134 | 1606 | 67 | 521 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2 |
| P9WN05 | 1.96e-12 | 1134 | 1606 | 67 | 521 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2 |
| L8F4Z2 | 2.54e-12 | 1134 | 1606 | 61 | 515 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as LIPO
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000000 | 0.000000 | 1.000075 | 0.000000 | 0.000000 | 0.000000 |
TMHMM Annotations download full data without filtering help
| start | end |
|---|---|
| 220 | 239 |
| 252 | 274 |
| 329 | 351 |
| 364 | 386 |
| 406 | 435 |
| 456 | 478 |
| 498 | 517 |
| 524 | 546 |
| 561 | 578 |
| 606 | 628 |
| 641 | 663 |
| 707 | 726 |
| 1203 | 1225 |
| 1256 | 1278 |
| 1304 | 1322 |
| 1362 | 1384 |
| 1454 | 1471 |
| 1511 | 1529 |
| 1533 | 1552 |
| 1564 | 1586 |