dbCAN-seq: a database of CAZyme sequence and annotation

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CAZyme Information: MGYG000004667_02309

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Basic Information help

Species

Clostridium beijerinckii

Lineage

Bacteria; Firmicutes_A; Clostridia; Clostridiales; Clostridiaceae; Clostridium; Clostridium beijerinckii

CAZyme ID

MGYG000004667_02309

CAZy Family

GH18

CAZyme Description

hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
610	MGYG000004667_51\|CGC1	65502.03	6.4995

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000004667	6180974	Isolate	United States	North America

Gene Location

Start: 20053; End: 21885 Strand: +

Full Sequence Download help

Enzyme Prediction help

No EC number prediction in MGYG000004667_02309.

CAZyme Signature Domains help

Family	Start	End	Evalue	family coverage
GH18	43	361	3.1e-25	0.9695945945945946
CBM12	566	598	2.6e-17	0.9411764705882353

CDD Domains download full data without filtering help

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd02871	GH18_chitinase_D-like	2.55e-123	43	365	1	312	GH18 domain of Chitinase D (ChiD). ChiD, a chitinase found in Bacillus circulans, hydrolyzes the 1,4-beta-linkages of N-acetylglucosamine in chitin and chitodextrins. The domain architecture of ChiD includes a catalytic glycosyl hydrolase family 18 (GH18) domain, a chitin-binding domain, and a fibronectin type III domain. The chitin-binding and fibronectin type III domains are located either N-terminal or C-terminal to the catalytic domain. This family includes exochitinase Chi36 from Bacillus cereus.
COG3469	Chi1	1.82e-54	20	374	1	330	Chitinase [Carbohydrate transport and metabolism].
cd12214	ChiA1_BD	2.45e-20	566	608	1	43	chitin-binding domain of Chi A1-like proteins. This group contains proteins related to the chitin binding domain of chitinase A1 (ChiA1) of Bacillus circulans WL-12. Glycosidase ChiA1 hydrolyzes chitin and is comprised of several domains: the C-terminal chitin binding domain, an N-terminal and catalytic domain, and 2 fibronectin type III-like domains. Chitinases function in invertebrates in the degradation of old exoskeletons, in fungi to utilize chitin in cell walls, and in bacteria which use chitin as an energy source. Bacillus circulans WL-12 ChiA1 facilitates invasion of fungal cell walls. The ChiAi chitin binding domain is required for the specific recognition of insoluble chitin. although topologically and structurally related, ChiA1 lacks the characteristic aromatic residues of Erwinia chrysanthemi endoglucanase Z (CBD(EGZ)).
pfam00704	Glyco_hydro_18	8.16e-20	44	351	1	307	Glycosyl hydrolases family 18.
cd00598	GH18_chitinase-like	2.26e-19	45	220	1	169	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods. Chitinases have been identified in viruses, bacteria, fungi, protozoan parasites, insects, and plants. The structure of the GH18 domain is an eight-stranded beta/alpha barrel with a pronounced active-site cleft at the C-terminal end of the beta-barrel. The GH18 family includes chitotriosidase, chitobiase, hevamine, zymocin-alpha, narbonin, SI-CLP (stabilin-1 interacting chitinase-like protein), IDGF (imaginal disc growth factor), CFLE (cortical fragment-lytic enzyme) spore hydrolase, the type III and type V plant chitinases, the endo-beta-N-acetylglucosaminidases, and the chitolectins. The GH85 (glycosyl hydrolase, family 85) ENGases (endo-beta-N-acetylglucosaminidases) are closely related to the GH18 chitinases and are included in this alignment model.

CAZyme Hits help

Hit ID	Query Start	Query End	Hit Start	Hit End
AQS05576.1	1	610	1	610
CUU48452.1	1	610	1	610
QUN33196.1	1	610	1	610
AVK46914.1	1	610	1	610
AJG99222.1	1	610	1	610

PDB Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
3N11_A	1.87e-106	38	370	2	330	Crystalstricture of wild-type chitinase from Bacillus cereus NCTU2 [Bacillus cereus],3N12_A Crystal stricture of chitinase in complex with zinc atoms from Bacillus cereus NCTU2 [Bacillus cereus]
3N15_A	5.26e-106	38	370	2	330	Crystalstricture of E145Q chitinase in complex with NAG from Bacillus cereus NCTU2 [Bacillus cereus]
3N18_A	7.42e-106	38	370	2	330	Crystalstricture of E145G/Y227F chitinase in complex with NAG from Bacillus cereus NCTU2 [Bacillus cereus],3N1A_A Crystal stricture of E145G/Y227F chitinase in complex with cyclo-(L-His-L-Pro) from Bacillus cereus NCTU2 [Bacillus cereus]
3N17_A	2.09e-105	38	370	2	330	Crystalstricture of E145Q/Y227F chitinase in complex with NAG from Bacillus cereus NCTU2 [Bacillus cereus]
3N13_A	2.94e-105	38	370	2	330	Crystalstricture of D143A chitinase in complex with NAG from Bacillus cereus NCTU2 [Bacillus cereus]

Swiss-Prot Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q05638	3.83e-118	37	366	258	596	Exochitinase 1 OS=Streptomyces olivaceoviridis OX=1921 GN=chi01 PE=1 SV=1
P27050	2.29e-105	27	371	164	516	Chitinase D OS=Niallia circulans OX=1397 GN=chiD PE=1 SV=4
D4AVJ0	3.93e-105	61	365	17	327	Probable class II chitinase ARB_00204 OS=Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331 GN=ARB_00204 PE=1 SV=2
A5FB63	2.53e-51	26	351	1122	1462	Chitinase ChiA OS=Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / JCM 8514 / NBRC 14942 / NCIMB 11054 / UW101) OX=376686 GN=chiA PE=1 SV=1
Q838S2	3.77e-31	8	351	4	325	Chitinase OS=Enterococcus faecalis (strain ATCC 700802 / V583) OX=226185 GN=EF_0361 PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000257	0.999102	0.000176	0.000173	0.000151	0.000132

TMHMM Annotations help

There is no transmembrane helices in MGYG000004667_02309.