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CAZyme Information: MGYG000004680_02624

You are here: Home > Sequence: MGYG000004680_02624

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Lacrimispora;
CAZyme ID MGYG000004680_02624
CAZy Family GH73
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
758 MGYG000004680_43|CGC1 80622.42 9.0912
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004680 3596809 MAG Germany Europe
Gene Location Start: 11699;  End: 13975  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000004680_02624.

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG4193 LytD 4.65e-17 348 498 106 245
Beta- N-acetylglucosaminidase [Carbohydrate transport and metabolism].
cd14256 Dockerin_I 1.01e-16 700 745 1 46
Type I dockerin repeat domain. Bacterial cohesin domains bind to a complementary protein domain named dockerin, and this interaction is required for the formation of the cellulosome, a cellulose-degrading complex. The cellulosome consists of scaffoldin, a noncatalytic scaffolding polypeptide, that comprises repeating cohesion modules and a single carbohydrate-binding module (CBM). Specific calcium-dependent interactions between cohesins and dockerins appear to be essential for cellulosome assembly. This subfamily represents type I dockerins, which are responsible for anchoring a variety of enzymatic domains to the complex.
pfam00404 Dockerin_1 2.34e-13 701 745 1 45
Dockerin type I repeat. The dockerin repeat is the binding partner of the cohesin domain pfam00963. The cohesin-dockerin interaction is the crucial interaction for complex formation in the cellulosome. The dockerin repeats, each bearing homology to the EF-hand calcium-binding loop bind calcium.
pfam08239 SH3_3 1.98e-10 46 107 1 54
Bacterial SH3 domain.
pfam12733 Cadherin-like 2.91e-10 518 598 1 88
Cadherin-like beta sandwich domain. This domain is found in several bacterial, metazoan and chlorophyte algal proteins. A profile-profile comparison recovered the cadherin domain and a comparison of the predicted structure of this domain with the crystal structure of the cadherin showed a congruent seven stranded secondary structure. The domain is widespread in bacteria and seen in the firmicutes, actinobacteria, certain proteobacteria, bacteroides and chlamydiae with an expansion in Clostridium. In contrast, it is limited in its distribution in eukaryotes suggesting that it was derived through lateral transfer from bacteria. In prokaryotes, this domain is widely fused to other domains such as FNIII (Fibronectin Type III), TIG, SLH (S-layer homology), discoidin, cell-wall-binding repeat domain and alpha-amylase-like glycohydrolases. These associations are suggestive of a carbohydrate-binding function for this cadherin-like domain. In animal proteins it is associated with an ATP-grasp domain.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QRV21758.1 0.0 1 725 1 747
ADL03932.1 0.0 1 725 1 747
SET60659.1 0.0 1 735 1 748
QJU23484.1 3.38e-225 1 608 1 693
ASN95383.1 7.44e-224 1 608 1 693

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
6FXO_A 1.94e-10 386 497 143 243
ChainA, Bifunctional autolysin [Staphylococcus aureus subsp. aureus Mu50]
4PI8_A 1.69e-09 369 481 108 212
ChainA, Autolysin E [Staphylococcus aureus subsp. aureus Mu50]
4PI7_A 2.28e-09 371 481 110 212
ChainA, Autolysin E [Staphylococcus aureus subsp. aureus Mu50],4PI9_A Chain A, Autolysin E [Staphylococcus aureus subsp. aureus Mu50],4PIA_A Chain A, Autolysin E [Staphylococcus aureus subsp. aureus Mu50]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q99V41 7.89e-09 386 497 1147 1247
Bifunctional autolysin OS=Staphylococcus aureus (strain N315) OX=158879 GN=atl PE=1 SV=1
Q931U5 7.89e-09 386 497 1147 1247
Bifunctional autolysin OS=Staphylococcus aureus (strain Mu50 / ATCC 700699) OX=158878 GN=atl PE=1 SV=2
A7X0T9 7.90e-09 386 497 1154 1254
Bifunctional autolysin OS=Staphylococcus aureus (strain Mu3 / ATCC 700698) OX=418127 GN=atl PE=3 SV=2
Q5HH31 7.90e-09 386 497 1155 1255
Bifunctional autolysin OS=Staphylococcus aureus (strain COL) OX=93062 GN=atl PE=3 SV=1
Q6GI31 7.90e-09 386 497 1156 1256
Bifunctional autolysin OS=Staphylococcus aureus (strain MRSA252) OX=282458 GN=atl PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.001195 0.997426 0.000501 0.000426 0.000213 0.000184

TMHMM  Annotations      download full data without filtering help

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