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CAZyme Information: MGYG000004719_01006

You are here: Home > Sequence: MGYG000004719_01006

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Roseburia sp900756925
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia; Roseburia sp900756925
CAZyme ID MGYG000004719_01006
CAZy Family GT11
CAZyme Description O-antigen biosynthesis glycosyltransferase WbnK
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
307 36098.14 6.2412
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004719 2432384 MAG China Asia
Gene Location Start: 26848;  End: 27771  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

EC 2.4.1.69

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT11 1 304 3.4e-59 0.9927536231884058

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd11301 Fut1_Fut2_like 1.49e-54 1 284 1 250
Alpha-1,2-fucosyltransferase. Alpha-1,2-fucosyltransferases (Fut1, Fut2) catalyze the transfer of alpha-L-fucose to the terminal beta-D-galactose residue of glycoconjugates via an alpha-1,2-linkage, generating carbohydrate structures that exhibit H-antigenicity for blood-group carbohydrates. These structures also act as ligands for morphogenesis, the adhesion of microbes, and metastasizing cancer cells. Fut1 is responsible for producing the H antigen on red blood cells. Fut2 is expressed in epithelia of secretory tissues, and individuals termed "secretors" have at least one functional copy of the gene; they secrete H antigen which is further processed into A and/or B antigens depending on the ABO genotype. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes.
pfam01531 Glyco_transf_11 1.96e-27 1 306 1 298
Glycosyl transferase family 11. This family contains several fucosyl transferase enzymes.
cd11548 NodZ_like 2.51e-04 111 278 110 284
Alpha 1,6-fucosyltransferase similar to Bradyrhizobium NodZ. Bradyrhizobium NodZ is an alpha 1,6-fucosyltransferase involved in the biosynthesis of the nodulation factor, a lipo-chitooligosaccharide formed by three-to-six beta-1,4-linked N-acetyl-d-glucosamine (GlcNAc) residues and a fatty acid acyl group attached to the nitrogen atom at the non-reducing end. NodZ transfers L-fucose from the GDP-beta-L-fucose donor to the reducing residue of the chitin oligosaccharide backbone, before the attachment of a fatty acid group. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
AFK59578.1 4.95e-68 1 307 1 301
AGY81956.1 5.79e-64 1 307 1 303
QJR72471.1 4.13e-54 1 307 1 326
QJR63873.1 4.13e-54 1 307 1 326
QJR68136.1 4.13e-54 1 307 1 326

PDB Hits      help

has no PDB hit.

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q58YV9 1.60e-16 6 302 5 299
O-antigen biosynthesis glycosyltransferase WbnK OS=Escherichia coli OX=562 GN=wbnK PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000051 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000004719_01006.