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CAZyme Information: MGYG000004730_00607
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Lysinibacillus fusiformis_D | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes; Bacilli; Bacillales_A; Planococcaceae; Lysinibacillus; Lysinibacillus fusiformis_D | |||||||||||
| CAZyme ID | MGYG000004730_00607 | |||||||||||
| CAZy Family | GT2 | |||||||||||
| CAZyme Description | Anguibactin system regulator | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 31; End: 2838 Strand: - | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd12114 | A_NRPS_TlmIV_like | 0.0 | 356 | 836 | 1 | 477 | The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes. The adenylation (A) domain of NRPS recognizes a specific amino acid or hydroxy acid and activates it as an (amino) acyl adenylate by hydrolysis of ATP. The activated acyl moiety then forms a thioester to the enzyme-bound cofactor phosphopantetheine of a peptidyl carrier protein domain. NRPSs are large multifunctional enzymes which synthesize many therapeutically useful peptides in bacteria and fungi via a template-directed, nucleic acid independent nonribosomal mechanism. These natural products include antibiotics, immunosuppressants, plant and animal toxins, and enzyme inhibitors. NRPS has a distinct modular structure in which each module is responsible for the recognition, activation, and in some cases, modification of a single amino acid residue of the final peptide product. The modules can be subdivided into domains that catalyze specific biochemical reactions. This family includes the TLM biosynthetic gene cluster from Streptoalloteichus that consists of nine NRPS genes; the N-terminal module of TlmVI (NRPS-5) and the starter module of BlmVI (NRPS-5) are comprised of the acyl CoA ligase (AL) and acyl carrier protein (ACP)-like domains, which are thought to be involved in the biosynthesis of the beta-aminoalaninamide moiety. |
| COG1020 | EntF | 6.79e-168 | 107 | 764 | 1 | 642 | Non-ribosomal peptide synthetase component F [Secondary metabolites biosynthesis, transport and catabolism]. |
| cd05930 | A_NRPS | 8.96e-165 | 356 | 834 | 1 | 442 | The adenylation domain of nonribosomal peptide synthetases (NRPS). The adenylation (A) domain of NRPS recognizes a specific amino acid or hydroxy acid and activates it as an (amino) acyl adenylate by hydrolysis of ATP. The activated acyl moiety then forms a thioester bond to the enzyme-bound cofactor phosphopantetheine of a peptidyl carrier protein domain. NRPSs are large multifunctional enzymes which synthesize many therapeutically useful peptides in bacteria and fungi via a template-directed, nucleic acid independent nonribosomal mechanism. These natural products include antibiotics, immunosuppressants, plant and animal toxins, and enzyme inhibitors. NRPS has a distinct modular structure in which each module is responsible for the recognition, activation, and in some cases, modification of a single amino acid residue of the final peptide product. The modules can be subdivided into domains that catalyze specific biochemical reactions. |
| PRK12467 | PRK12467 | 2.41e-155 | 18 | 929 | 184 | 1103 | peptide synthase; Provisional |
| PRK12316 | PRK12316 | 2.54e-145 | 18 | 933 | 184 | 1095 | peptide synthase; Provisional |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AFZ04852.1 | 2.03e-106 | 66 | 935 | 317 | 1195 |
| BAY30132.1 | 8.49e-100 | 17 | 925 | 2380 | 3296 |
| QND46664.1 | 2.77e-99 | 4 | 928 | 1734 | 2667 |
| BAY90071.1 | 1.02e-97 | 17 | 925 | 2369 | 3285 |
| BAZ00088.1 | 3.36e-97 | 17 | 925 | 2378 | 3294 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 7LY7_A | 4.21e-190 | 4 | 925 | 129 | 1018 | ChainA, BmdB, Bacillamide NRPS [Thermoactinomyces vulgaris] |
| 7LY4_E | 4.33e-190 | 4 | 925 | 129 | 1018 | ChainE, BmdB, bacillamide NRPS [Thermoactinomyces vulgaris] |
| 6LTA_A | 8.65e-161 | 8 | 923 | 177 | 1098 | ChainA, Nonribosomal peptide synthetase [Streptomyces sp. Sp080513GE-23],6LTB_A Chain A, Nonribosomal peptide synthetase [Streptomyces sp. Sp080513GE-23],6LTC_A Chain A, Nonribosomal peptide synthetase [Streptomyces sp. Sp080513GE-23],6LTD_A Chain A, Nonribosomal peptide synthetase [Streptomyces sp. Sp080513GE-23],6LTD_B Chain B, Nonribosomal peptide synthetase [Streptomyces sp. Sp080513GE-23] |
| 7EMY_A | 3.61e-124 | 8 | 773 | 227 | 976 | ChainA, Dihydroaeruginoic acid synthetase [Pseudomonas aeruginosa PAO1],7EMY_B Chain B, Dihydroaeruginoic acid synthetase [Pseudomonas aeruginosa PAO1],7EN1_A Chain A, Dihydroaeruginoic acid synthetase [Pseudomonas aeruginosa PAO1],7EN1_B Chain B, Dihydroaeruginoic acid synthetase [Pseudomonas aeruginosa PAO1],7EN2_A Chain A, Dihydroaeruginoic acid synthetase [Pseudomonas aeruginosa PAO1],7EN2_B Chain B, Dihydroaeruginoic acid synthetase [Pseudomonas aeruginosa PAO1] |
| 6MFZ_A | 1.33e-110 | 17 | 934 | 910 | 1808 | Crystalstructure of dimodular LgrA in a condensation state [Brevibacillus parabrevis],6MFZ_B Crystal structure of dimodular LgrA in a condensation state [Brevibacillus parabrevis] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| O68006 | 2.66e-174 | 7 | 926 | 757 | 1654 | Bacitracin synthase 1 OS=Bacillus licheniformis OX=1402 GN=bacA PE=3 SV=1 |
| Q9HWG4 | 1.39e-165 | 3 | 793 | 187 | 965 | Pyochelin synthase PchF OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) OX=208964 GN=pchF PE=2 SV=1 |
| A0A0H2ZGJ4 | 9.81e-164 | 3 | 793 | 187 | 965 | Pyochelin synthase PchF OS=Pseudomonas aeruginosa (strain UCBPP-PA14) OX=208963 GN=pchF PE=1 SV=1 |
| P48633 | 2.84e-152 | 1 | 791 | 231 | 1009 | High-molecular-weight protein 2 OS=Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081) OX=393305 GN=irp2 PE=3 SV=1 |
| P0DJH0 | 2.85e-149 | 2 | 934 | 128 | 1046 | Anguibactin system regulator OS=Vibrio anguillarum OX=55601 GN=angR PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000073 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |