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CAZyme Information: MGYG000004748_00987

You are here: Home > Sequence: MGYG000004748_00987

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides;
CAZyme ID MGYG000004748_00987
CAZy Family PL12
CAZyme Description Heparin-sulfate lyase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
665 MGYG000004748_3|CGC5 77455.44 6.7024
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004748 4696076 MAG China Asia
Gene Location Start: 334420;  End: 336417  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 4.2.2.8

CAZyme Signature Domains help

Family Start End Evalue family coverage
PL12 403 533 7.7e-65 0.9923664122137404

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam16889 Hepar_II_III_N 0.0 29 382 1 344
Heparinase II/III N-terminus. This is the N-terminal domain of heparinase II/III proteins. It is a toroid-like domain.
pfam07940 Hepar_II_III 3.23e-35 394 618 3 232
Heparinase II/III-like protein. This family features sequences that are similar to a region of the Flavobacterium heparinum proteins heparinase II and heparinase III. The former is known to degrade heparin and heparin sulphate, whereas the latter predominantly degrades heparin sulphate. Both are secreted into the periplasmic space upon induction with heparin.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
ALJ58957.1 0.0 1 661 1 661
QUT89926.1 0.0 1 661 1 661
ADV43619.1 0.0 1 661 1 661
QDO67526.1 0.0 1 661 1 661
QRQ49787.1 0.0 1 665 1 665

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5JMD_A 0.0 21 661 11 651
HeparinaseIII-BT4657 gene product, Methylated Lysines [Bacteroides thetaiotaomicron VPI-5482]
5JMF_A 0.0 21 661 11 651
HeparinaseIII-BT4657 gene product [Bacteroides thetaiotaomicron VPI-5482]
4MMH_A 1.84e-196 20 659 1 630
Crystalstructure of heparan sulfate lyase HepC from Pedobacter heparinus [Pedobacter heparinus]
4MMI_A 1.84e-196 20 662 1 633
Crystalstructure of heparan sulfate lyase HepC mutant from Pedobacter heparinus [Pedobacter heparinus]
4FNV_A 8.15e-130 27 662 48 699
CrystalStructure of Heparinase III [Bacteroides thetaiotaomicron VPI-5482]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
C7EXL6 0.0 21 661 22 662
Heparin-sulfate lyase OS=Bacteroides stercoris OX=46506 GN=hepC PE=1 SV=1
Q59289 1.71e-195 20 659 25 654
Heparin-sulfate lyase OS=Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3) OX=485917 GN=hepC PE=1 SV=1
Q89YR9 4.46e-129 27 662 48 699
Heparin-sulfate lyase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=hepC PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000237 0.999102 0.000176 0.000155 0.000149 0.000141

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000004748_00987.