| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes; Bacilli; RF39; UBA660; RUG705; | |||||||||||
| CAZyme ID | MGYG000004753_00397 | |||||||||||
| CAZy Family | GT51 | |||||||||||
| CAZyme Description | Penicillin-binding protein 2D | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 57683; End: 59716 Strand: + | |||||||||||
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT51 | 55 | 219 | 1.1e-63 | 0.9322033898305084 |
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG0744 | MrcB | 0.0 | 11 | 592 | 23 | 603 | Membrane carboxypeptidase (penicillin-binding protein) [Cell wall/membrane/envelope biogenesis]. |
| COG5009 | MrcA | 1.99e-148 | 1 | 652 | 2 | 785 | Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]. |
| COG4953 | PbpC | 3.18e-85 | 11 | 563 | 4 | 538 | Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis]. |
| pfam00912 | Transgly | 7.31e-83 | 49 | 219 | 1 | 176 | Transglycosylase. The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains. |
| PRK11636 | mrcA | 1.17e-71 | 1 | 631 | 1 | 828 | penicillin-binding protein 1a; Provisional |
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QNU38784.1 | 1.36e-178 | 59 | 631 | 76 | 653 |
| QXJ38547.1 | 5.43e-178 | 59 | 631 | 76 | 653 |
| AEH49664.1 | 1.05e-177 | 2 | 631 | 14 | 653 |
| APM79991.1 | 5.95e-177 | 2 | 631 | 14 | 653 |
| ANZ29253.1 | 5.95e-177 | 2 | 631 | 14 | 653 |
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 3DWK_A | 2.34e-67 | 45 | 602 | 10 | 604 | ChainA, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_B Chain B, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_C Chain C, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_D Chain D, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL] |
| 4OON_A | 6.07e-67 | 64 | 610 | 46 | 747 | Crystalstructure of PBP1a in complex with compound 17 ((4Z,8S,11E,14S)-5-(2-amino-1,3-thiazol-4-yl)-14-(5,6-dihydroxy-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-8-formyl-2-methyl-6-oxo-3,10-dioxa-4,7,11-triazatetradeca-4,11-diene-2,12,14-tricarboxylic acid) [Pseudomonas aeruginosa PAO1] |
| 2OLU_A | 1.30e-63 | 45 | 602 | 19 | 613 | StructuralInsight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Apoenzyme [Staphylococcus aureus],2OLV_A Structural Insight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Donor Ligand Complex [Staphylococcus aureus],2OLV_B Structural Insight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Donor Ligand Complex [Staphylococcus aureus] |
| 5U2G_A | 1.80e-58 | 60 | 631 | 43 | 800 | 2.6Angstrom Resolution Crystal Structure of Penicillin-Binding Protein 1A from Haemophilus influenzae [Haemophilus influenzae Rd KW20],5U2G_B 2.6 Angstrom Resolution Crystal Structure of Penicillin-Binding Protein 1A from Haemophilus influenzae [Haemophilus influenzae Rd KW20] |
| 5FGZ_A | 2.24e-58 | 69 | 564 | 168 | 672 | E.coli PBP1b in complex with FPI-1465 [Escherichia coli K-12],5HL9_A E. coli PBP1b in complex with acyl-ampicillin and moenomycin [Escherichia coli K-12],5HLA_A E. coli PBP1b in complex with acyl-cephalexin and moenomycin [Escherichia coli K-12],5HLB_A E. coli PBP1b in complex with acyl-aztreonam and moenomycin [Escherichia coli K-12],5HLD_A E. coli PBP1b in complex with acyl-CENTA and moenomycin [Escherichia coli K-12],6YN0_A Structure of E. coli PBP1b with a FtsN peptide activating transglycosylase activity [Escherichia coli K-12],7LQ6_A Chain A, Penicillin-binding protein 1B [Escherichia coli K-12] |
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P70997 | 4.53e-162 | 32 | 631 | 46 | 653 | Penicillin-binding protein 2D OS=Bacillus subtilis (strain 168) OX=224308 GN=pbpG PE=2 SV=3 |
| O66874 | 3.69e-78 | 59 | 633 | 65 | 714 | Penicillin-binding protein 1A OS=Aquifex aeolicus (strain VF5) OX=224324 GN=mrcA PE=1 SV=1 |
| P0A0Z5 | 6.72e-74 | 45 | 601 | 52 | 721 | Penicillin-binding protein 1A OS=Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 / Z2491) OX=122587 GN=mrcA PE=3 SV=1 |
| P0A0Z6 | 6.72e-74 | 45 | 601 | 52 | 721 | Penicillin-binding protein 1A OS=Neisseria meningitidis serogroup B (strain MC58) OX=122586 GN=mrcA PE=3 SV=1 |
| P38050 | 2.90e-73 | 47 | 597 | 53 | 616 | Penicillin-binding protein 1F OS=Bacillus subtilis (strain 168) OX=224308 GN=pbpF PE=2 SV=2 |
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.999927 | 0.000079 | 0.000001 | 0.000000 | 0.000000 | 0.000004 |
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