CAZyme Information: MGYG000004757_00721

Basic Information

• Species: UBA6398 sp900555645
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; UBA6398; UBA6398 sp900555645
• CAZyme ID: MGYG000004757_00721
• CAZy Family: GT2
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
820	MGYG000004757_37|CGC1	93676.76	8.8614

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000004757	2504990	MAG	China	Asia

• Gene Location: Start: 2833; End: 5295 Strand: -

Full Sequence      

MINKKIKCYIISNASEVTAQNIDEFRKNGYKQPVCSIKIIGDTQALSKNDNENKDSTPFF
TVKSPESTDTLVKILKHTDTPYILWFKKASAMKLAEKSLQTMVETAERTNAAIVFANHYD
VKNGVREEHPLIDYTEGSVTDDFDFGSLLLISVKSLEEYLKAHTASRYQYAGFYDFRLFA
GKKHPIVRIDEYLYDEIETDLRLSGQKQFDYVDPRNRRRQIEMERAFTEYLKEINAFIPP
YEAKRVDFTKEAFECEASVIIPVRNRVKTVKDAVESALSQKTKFPFNVIVVDNHSTDGTT
DVLKQLSSNKQLVHIIPKRTDLGIGGCWELAVKNKKCGRFAVQLDSDDLYADENTLQTIV
NKFYRTHAAMVIGSYRMVDFKLNTLPPGIIDHKEWTSENGRNNALRINGLGAPRAFYTPI
LRKTGVPNTSYGEDYALGLVFSREYYIARIFDVVYLCRRWEGNSDAALSQVKTNKNNAYK
NSLRAEEINKRRKLNILRQHHVKQNETINFFNKQLKCWKEVDTRFEQLKNVQTRNLSIGN
VSLTAQFNPARIVSTGAKVDKRSISKRPCFLCDNNRPKEQINLPVEERYQVLINPFPILP
NHITVTSRFHEPQSIGGRYHTLVNIAKSLSDFVVFYNGPTSGASAPDHMHFQAGARGVMP
LEKDWNKYSLDSKALYTPDNATEGEGIYEITSYACPAVAIVANTDKRSVYLFNKLYSVLN
GKIDGVEYPMNVISWNENEKLVTVIFLRKKLRPECYSAQGDEQFIISPGSVDMCGLLITP
RKEDFERLTPEKAVSILKEVTISKEDIEKIGRELYAKESL

Enzyme Prediction     

No EC number prediction in MGYG000004757_00721.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT2	258	384	2e-20	0.7294117647058823

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam16269	DUF4922	5.98e-87	618	808	1	188	Domain of unknown function (DUF4922). This family consists of uncharacterized proteins around 310 residues in length and is mainly found in various Bacteroides and Parabacteroides species. Several members are annotated as putative glycosyltransferases, but the specific function of this family is still unknown.
cd00761	Glyco_tranf_GTA_type	1.17e-18	259	378	1	118	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.
pfam00535	Glycos_transf_2	1.18e-18	258	416	1	156	Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.
cd06433	GT_2_WfgS_like	2.77e-13	258	465	1	200	WfgS and WfeV are involved in O-antigen biosynthesis. Escherichia coli WfgS and Shigella dysenteriae WfeV are glycosyltransferase 2 family enzymes involved in O-antigen biosynthesis. GT-2 enzymes have GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.
cd02525	Succinoglycan_BP_ExoA	1.28e-12	258	376	3	119	ExoA is involved in the biosynthesis of succinoglycan. Succinoglycan Biosynthesis Protein ExoA catalyzes the formation of a beta-1,3 linkage of the second sugar (glucose) of the succinoglycan with the galactose on the lipid carrie. Succinoglycan is an acidic exopolysaccharide that is important for invasion of the nodules. Succinoglycan is a high-molecular-weight polymer composed of repeating octasaccharide units. These units are synthesized on membrane-bound isoprenoid lipid carriers, beginning with galactose followed by seven glucose molecules, and modified by the addition of acetate, succinate, and pyruvate. ExoA is a membrane protein with a transmembrance domain at c-terminus.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QUB41125.1	3.00e-281	67	814	64	799
QUB65927.1	6.98e-281	4	814	5	797
QUB69156.1	3.14e-279	4	814	5	797
QUB57862.1	3.54e-278	4	814	5	797
QUB56535.1	3.54e-278	4	814	5	797

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000063	0.000012	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000004757_00721.