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CAZyme Information: MGYG000004781_01258
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; UMGS680; | |||||||||||
| CAZyme ID | MGYG000004781_01258 | |||||||||||
| CAZy Family | GH2 | |||||||||||
| CAZyme Description | Beta-glucuronidase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 7959; End: 9746 Strand: + | |||||||||||
Full Sequence Download help
| MLYPKMSKTR MVFSLDGVWD FQLATEEVKP SKKLEDSIPM PVPSSYNDIY IGRDFKNHVG | 60 |
| NMVYQRTIAI TEQMLEKRLV LRFGSATHKA EVFLNGEYIG GHKGGFLPFE FEITKFANVG | 120 |
| ENLLTVVVDN IIDHTTLPAG RIVNQTFPNM EPEIHNLPNF DFFNYSGLMR SVQLYTTDKN | 180 |
| YIKDIVIFGD DKGNMEWNVL VEGEETLSVQ VEILDKEGHC VYQGQGRSGK ARIIPCELWD | 240 |
| TENPYLYRAK VTLRKGQELL DEYTETFGFR TITIENCRLY LNGKKLYLRG FGKHEDAPIS | 300 |
| GRGLNLPYHI KDLALMKWMG ANSFRSSHYP YSEEMLNLCD QEGILVISEA PAVGLHTGFT | 360 |
| ATGMIGGEPK GTWTTLKTAE HHREVIEDMI RRDKNHPCVV MWSVANEPAS EEEGAKEYFE | 420 |
| PLTTLAKEKD PQHRPVTIVT YEGSSPEKCK VAELCDVLVI NRYRGWYDTE GNLKGAAALL | 480 |
| KNELERFHKR CPEKPIMLGE YGVDTIAGMH DIDGGLFSEE YQVAFLKTYS EVFDSLPYIT | 540 |
| GEHVWNFADF ATAENIKRVQ GNKKGIFTRT REPKMSAYYM KQRWNEMKEK ENSYE | 595 |
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH2 | 7 | 586 | 4.4e-109 | 0.6170212765957447 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| PRK10150 | PRK10150 | 0.0 | 1 | 587 | 1 | 595 | beta-D-glucuronidase; Provisional |
| COG3250 | LacZ | 1.10e-109 | 9 | 574 | 9 | 585 | Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism]. |
| pfam02836 | Glyco_hydro_2_C | 1.06e-77 | 272 | 584 | 1 | 297 | Glycosyl hydrolases family 2, TIM barrel domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities. |
| PRK10340 | ebgA | 2.51e-50 | 63 | 549 | 112 | 547 | cryptic beta-D-galactosidase subunit alpha; Reviewed |
| PRK09525 | lacZ | 7.94e-40 | 14 | 407 | 54 | 462 | beta-galactosidase. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AWY98908.1 | 2.88e-297 | 1 | 587 | 1 | 593 |
| QOV20331.1 | 1.46e-295 | 1 | 588 | 1 | 592 |
| QCX33671.1 | 3.26e-220 | 1 | 584 | 1 | 588 |
| BAB79853.1 | 5.13e-217 | 1 | 589 | 1 | 594 |
| QQA12223.1 | 7.27e-217 | 1 | 589 | 1 | 594 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 4JKM_A | 2.08e-218 | 1 | 589 | 4 | 597 | CrystalStructure of Clostridium perfringens beta-glucuronidase [Clostridium perfringens str. 13],4JKM_B Crystal Structure of Clostridium perfringens beta-glucuronidase [Clostridium perfringens str. 13],6CXS_A Crystal Structure of Clostridium perfringens beta-glucuronidase bound with a novel, potent inhibitor 4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine [Clostridium perfringens str. 13],6CXS_B Crystal Structure of Clostridium perfringens beta-glucuronidase bound with a novel, potent inhibitor 4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine [Clostridium perfringens str. 13] |
| 6BO6_A | 2.55e-188 | 1 | 589 | 1 | 605 | Eubacteriumeligens beta-glucuronidase bound to UNC4917 glucuronic acid conjugate [[Eubacterium] eligens ATCC 27750] |
| 6BJQ_A | 5.47e-188 | 1 | 589 | 25 | 629 | ChainA, Glycoside Hydrolase Family 2 candidate b-glucuronidase [[Eubacterium] eligens ATCC 27750] |
| 6BJW_A | 5.65e-188 | 1 | 589 | 25 | 629 | ChainA, Glycoside Hydrolase Family 2 candidate b-glucuronidase [[Eubacterium] eligens ATCC 27750] |
| 6D4O_A | 1.13e-187 | 1 | 589 | 4 | 608 | Eubacteriumeligens beta-glucuronidase bound to an amoxapine-glucuronide conjugate [Lachnospira eligens] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P05804 | 4.65e-148 | 1 | 587 | 1 | 591 | Beta-glucuronidase OS=Escherichia coli (strain K12) OX=83333 GN=uidA PE=1 SV=2 |
| P06760 | 3.30e-142 | 1 | 584 | 27 | 622 | Beta-glucuronidase OS=Rattus norvegicus OX=10116 GN=Gusb PE=1 SV=1 |
| O97524 | 2.26e-140 | 1 | 584 | 27 | 625 | Beta-glucuronidase OS=Felis catus OX=9685 GN=GUSB PE=1 SV=1 |
| P12265 | 1.15e-136 | 1 | 584 | 27 | 622 | Beta-glucuronidase OS=Mus musculus OX=10090 GN=Gusb PE=1 SV=2 |
| Q4FAT7 | 1.02e-135 | 1 | 584 | 28 | 626 | Beta-glucuronidase OS=Sus scrofa OX=9823 GN=GUSB PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000076 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |