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CAZyme Information: MGYG000004823_00533
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | CAG-462 sp900765575 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; CAG-462; CAG-462 sp900765575 | |||||||||||
| CAZyme ID | MGYG000004823_00533 | |||||||||||
| CAZy Family | GT9 | |||||||||||
| CAZyme Description | ADP-heptose--LPS heptosyltransferase 2 | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 7435; End: 8466 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT9 | 72 | 323 | 7.3e-37 | 0.9688888888888889 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd03789 | GT9_LPS_heptosyltransferase | 8.75e-56 | 3 | 340 | 1 | 277 | lipopolysaccharide heptosyltransferase and similar proteins. Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. |
| COG0859 | RfaF | 3.64e-46 | 1 | 342 | 1 | 330 | ADP-heptose:LPS heptosyltransferase [Cell wall/membrane/envelope biogenesis]. |
| pfam01075 | Glyco_transf_9 | 1.35e-15 | 72 | 316 | 3 | 242 | Glycosyltransferase family 9 (heptosyltransferase). Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core. |
| PRK10422 | PRK10422 | 2.51e-11 | 2 | 303 | 6 | 306 | lipopolysaccharide core biosynthesis protein; Provisional |
| PRK10916 | PRK10916 | 5.41e-05 | 1 | 286 | 1 | 292 | ADP-heptose--LPS heptosyltransferase RfaF. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| ALJ59711.1 | 1.57e-151 | 1 | 339 | 1 | 339 |
| QUT89241.1 | 2.22e-151 | 1 | 339 | 1 | 339 |
| QQT78204.1 | 4.90e-148 | 1 | 343 | 1 | 343 |
| ASM65268.1 | 4.90e-148 | 1 | 343 | 1 | 343 |
| QUU07102.1 | 4.90e-148 | 1 | 343 | 1 | 343 |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q9R9D5 | 2.21e-08 | 13 | 284 | 5 | 279 | Lipopolysaccharide core heptosyltransferase RfaQ OS=Escherichia coli OX=562 GN=rfaQ PE=1 SV=1 |
| Q57336 | 7.26e-08 | 2 | 340 | 9 | 343 | Lipopolysaccharide core heptosyltransferase OpsX OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=opsX PE=3 SV=1 |
| P37692 | 5.51e-07 | 3 | 286 | 2 | 292 | ADP-heptose--LPS heptosyltransferase 2 OS=Escherichia coli (strain K12) OX=83333 GN=rfaF PE=1 SV=1 |
| P45042 | 1.30e-06 | 3 | 286 | 2 | 292 | ADP-heptose--LPS heptosyltransferase 2 OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=rfaF PE=3 SV=1 |
| P25742 | 1.73e-06 | 13 | 303 | 5 | 294 | Lipopolysaccharide core heptosyltransferase RfaQ OS=Escherichia coli (strain K12) OX=83333 GN=rfaQ PE=3 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.882822 | 0.112185 | 0.004619 | 0.000150 | 0.000092 | 0.000145 |