CAZyme Information: MGYG000004824_00766

Basic Information

• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Paraprevotella
• CAZyme ID: MGYG000004824_00766
• CAZy Family: GH127
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
816		91970.96	6.6766

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000004824	2984736	MAG	China	Asia

• Gene Location: Start: 110589; End: 113039 Strand: +

Full Sequence      

MKNIYLTGLVCLFSSLSISAQEPALLPKRLSPVNFTQVHFQDSFWLPKINVNRKVSIPSA
FNECEKNGRFDNFALAAGLIKGEHKGDFSFDDTDPYKVIEGASYALATCYDSKLDAYLDS
VIHIIAAAQEPDGYLCTCVTNKCTRLSGWWGKSRWEKINSHELYNCGHLYEAAVAHYLAT
GKRTLLDVAVKNADLVCRVFGPSEGQIHRPSGHPIIEMALCKLYQVTGKQDYLDMARYFV
EETGRGTDGHQLSAYSQDHMPILQQEEIVGHAVRAGYLYSGVADVAALTGDTAYFHALLR
LWDNMANKKLYVTGGIGSRAQGEGFGPEYELNNHTAYCETCASIANVYWNHRMFLSTGDS
RFIDVLERALYNGVISGVSLSGDRFFYDNPLESMGQHDRQRWFGCACCPGNITRFMASVP
GYVYAMQGNHIYVNLWISNTASLKNDDMDITISQQSGLPWHAGLSLTVNCRKKQNVALHL
RIPAWLTDRFLPGSDLYEYATPAGRYVVTVNGKVVKGVMDKGYLVIDRRWKDGDKVHVDF
DMPVRRIHANNKVEDDLQKTALQRGPLVYCLEGIDQPDGEVFNKYLTAQSRFYPADSAQM
LGGITVLQGNVMRVPDEGDSQGREQQSKATAVPYYSWDNRGPGQMAVWLPETAEVTRPVL
KPSLASRARSVMIKAPIQKDAPVSASTEEWAFGVNDGWESKSSHDTSKPYFYWWLKRGSR
ETLAYTFEQPETLHSVSVYWLEMDHYDGNYRVPTWWKLYYKDNDTWKEVKALSPYGVKTD
QYNKVEFEPVTTTTLKMEVQLQPGQSGGVLEWKLNQ

Enzyme Prediction     

No EC number prediction in MGYG000004824_00766.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH127	38	570	7.7e-203	0.9980916030534351

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam07944	Glyco_hydro_127	0.0	37	570	1	503	Beta-L-arabinofuranosidase, GH127. One member of this family, from Bidobacterium longicum, UniProtKB:E8MGH8, has been characterized as an unusual beta-L-arabinofuranosidase enzyme, EC:3.2.1.185. It rleases l-arabinose from the l-arabinofuranose (Araf)-beta1,2-Araf disaccharide and also transglycosylates 1-alkanols with retention of the anomeric configuration. Terminal beta-l-arabinofuranosyl residues have been found in arabinogalactan proteins from a mumber of different plantt species. beta-l-Arabinofuranosyl linkages with 1-4 arabinofuranosides are also found in the sugar chains of extensin and solanaceous lectins, hydroxyproline (Hyp)2-rich glycoproteins that are widely observed in plant cell wall fractions. The critical residue for catalytic activity is Glu-338, in a ET/SCAS sequence context.
COG3533	COG3533	2.60e-175	71	651	40	587	Uncharacterized conserved protein, DUF1680 family [Function unknown].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AII61674.1	0.0	30	815	31	811
AND19021.1	0.0	30	815	31	811
QJR70306.1	0.0	30	815	31	811
QJR70728.1	0.0	30	815	31	811
QDO71484.1	0.0	30	815	31	811

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6EX6_A	3.74e-207	30	656	7	630	TheGH127, Beta-arabinofuranosidase, BT3674 [Bacteroides thetaiotaomicron VPI-5482],6EX6_B The GH127, Beta-arabinofuranosidase, BT3674 [Bacteroides thetaiotaomicron VPI-5482]
4QJY_A	7.31e-143	36	651	14	647	Crystalstructure of native Ara127N, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QJY_B Crystal structure of native Ara127N, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus]
4QK0_A	1.06e-138	36	651	14	647	Crystalstructure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_B Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_C Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_D Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus]
3WRE_A	2.24e-110	72	648	56	655	Thecrystal structure of native HypBA1 from Bifidobacterium longum JCM 1217 [Bifidobacterium longum subsp. longum JCM 1217],3WRG_A The complex structure of HypBA1 with L-arabinose [Bifidobacterium longum subsp. longum JCM 1217]
3WKW_A	3.00e-110	72	648	56	655	Crystalstructure of GH127 beta-L-arabinofuranosidase HypBA1 from Bifidobacterium longum ligand free form [Bifidobacterium longum subsp. longum JCM 1217],3WKX_A Crystal structure of GH127 beta-L-arabinofuranosidase HypBA1 from Bifidobacterium longum arabinose complex form [Bifidobacterium longum subsp. longum JCM 1217],7BZL_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217],7DIF_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217],7EXV_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217],7EXW_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
E8MGH8	1.23e-109	72	648	56	655	Non-reducing end beta-L-arabinofuranosidase OS=Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b) OX=565042 GN=hypBA1 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000330	0.999039	0.000162	0.000168	0.000146	0.000138

TMHMM  Annotations     

There is no transmembrane helices in MGYG000004824_00766.