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CAZyme Information: MGYG000004849_00738

You are here: Home > Sequence: MGYG000004849_00738

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; UMGS1826;
CAZyme ID MGYG000004849_00738
CAZy Family GH2
CAZyme Description Exo-beta-D-glucosaminidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
808 MGYG000004849_17|CGC1 92267.24 5.0139
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004849 3246607 MAG China Asia
Gene Location Start: 14183;  End: 16609  Strand: -

Full Sequence      Download help

MIKLSLNGAW  EMHPAGSDKW  FPATVPGSVY  SDLLSAGKME  DPYWRDNERK  ATVLMEQDYI60
YERDFFAERD  LSACEQVLLR  CEGLDTLAEV  YLNGRLAGYA  DNMHRIWEFD  VKELLLEGRN120
HFSICFRSPN  QAVRTAYEKS  RADGIAEAMK  GFPHIRKAHY  MYGWDWGPRL  PDAGIWRDIS180
LLGISQGRIE  EVQLHQIHQN  GQVSLTIHTA  VKGCGSIRIE  IACPDGQVLY  ASGTDACLTI240
KSPQLWWPRG  LGSQPLYRVT  VTLSDGERLL  DQWSKRIGLR  EVSLCRKKDR  WGESFAHAIN300
GVAFFALGVN  YIPEDNLLSR  VTPERTRRLL  EDAAAANFNL  IRVWGGGYYP  DDSFFDVCDE360
LGLVVWQDLM  FSCAVYDLTE  AFEETVCREI  ADNVRRIRHH  ACLCLWCGNN  EMEMFMDTGK420
YFQSYSQKAD  YTKMYEYIFP  KLLNELDPDT  PYWPSSPSSG  GGFDFPNDPT  RGDVHYWEVW480
HGGLPFTDYR  NHFFRYVSEF  GFQSFPCLET  IESFTEPEDR  NIFSYVMEKH  QRNAAANGKI540
LQYLAQLYRY  PATLEGIVYA  SQLLQAQAMQ  YGVEHWRRNR  DGGRCMGAVI  WQLNDCWPVA600
SWSSIDYFGR  WKALHYYAKR  FQSPVLLSCL  EEGSLLEYPD  VNAEAPLPIP  AAQLNVSNET660
QNAFSGRVTW  RLRQAADGAV  LQSATVSVQV  PPLSALWLER  IEFPDMDIRA  QYLEYVLEQD720
GTEISSGTTL  FCPPKYFAFA  DPALSVLVCG  DVITVRAQSY  ARSVEIRSED  PNAVFSDNYF780
DMSPGERSIT  LLRGTASRLS  VRSVFDIR808

Enzyme Prediction      help

No EC number prediction in MGYG000004849_00738.

CAZyme Signature Domains help

Created with Snap40801211612022422823233634044444845255656066466867277673694GH2
Family Start End Evalue family coverage
GH2 3 694 2.4e-111 0.6821808510638298

CDD Domains      download full data without filtering help

Created with Snap40801211612022422823233634044444845255656066466867277675781LacZ60437ebgA653736Mannosidase_ig173451PRK10150188280Glyco_hydro_2
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG3250 LacZ 7.86e-98 5 781 14 799
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10340 ebgA 7.23e-16 60 437 112 474
cryptic beta-D-galactosidase subunit alpha; Reviewed
pfam17786 Mannosidase_ig 1.18e-12 653 736 4 91
Mannosidase Ig/CBM-like domain. This domain corresponds to domain 4 in the structure of Bacteroides thetaiotaomicron beta-mannosidase, BtMan2A. This domain has an Ig-like fold.
PRK10150 PRK10150 1.42e-11 173 451 168 444
beta-D-glucuronidase; Provisional
pfam00703 Glyco_hydro_2 2.80e-11 188 280 2 106
Glycosyl hydrolases family 2. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.

CAZyme Hits      help

Created with Snap40801211612022422823233634044444845255656066466867277671808QTE69834.1|GH21808QTE73768.1|GH21808AHF25196.1|GH21808AHF25065.1|GH21808AUS95659.1|GH2
Hit ID E-Value Query Start Query End Hit Start Hit End
QTE69834.1 0.0 1 808 1 811
QTE73768.1 0.0 1 808 1 811
AHF25196.1 0.0 1 808 1 823
AHF25065.1 0.0 1 808 1 810
AUS95659.1 0.0 1 808 1 803

PDB Hits      download full data without filtering help

Created with Snap408012116120224228232336340444448452556560664668672776718086BYE_A18086BYC_A18086BYI_A18086BYG_A67922VJX_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
6BYE_A 8.75e-157 1 808 3 848
Crystalstructure of the GH2 exo-beta-mannanase from Xanthomonas axonopodis pv. citri in complex with mannose [Xanthomonas citri pv. citri str. 306],6BYE_B Crystal structure of the GH2 exo-beta-mannanase from Xanthomonas axonopodis pv. citri in complex with mannose [Xanthomonas citri pv. citri str. 306]
6BYC_A 9.00e-157 1 808 3 848
Crystalstructure of the GH2 exo-beta-mannanase from Xanthomonas axonopodis pv. citri [Xanthomonas citri pv. citri str. 306]
6BYI_A 6.44e-156 1 808 1 846
Crystalstructure of the acid-base mutant (E477A) of the GH2 exo-beta-mannanase from Xanthomonas axonopodis pv. citri [Xanthomonas citri pv. citri str. 306],6BYI_B Crystal structure of the acid-base mutant (E477A) of the GH2 exo-beta-mannanase from Xanthomonas axonopodis pv. citri [Xanthomonas citri pv. citri str. 306]
6BYG_A 6.62e-156 1 808 3 848
Crystalstructure of the nucleophile mutant (E575A) of the GH2 exo-beta-mannanase from Xanthomonas axonopodis pv. citri [Xanthomonas citri pv. citri str. 306],6BYG_B Crystal structure of the nucleophile mutant (E575A) of the GH2 exo-beta-mannanase from Xanthomonas axonopodis pv. citri [Xanthomonas citri pv. citri str. 306]
2VJX_A 1.95e-150 6 792 11 816
Structuraland biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VJX_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VQT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VQT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VR4_A Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482],2VR4_B Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482]

Swiss-Prot Hits      download full data without filtering help

Created with Snap40801211612022422823233634044444845255656066466867277676794sp|Q5B7W2|MANBB_EMENI6794sp|A1D911|MANBB_NEOFI6794sp|Q4WAH4|MANBB_ASPFU6794sp|B0YBU9|MANBB_ASPFC5786sp|A2QYN2|MANBB_ASPNC
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q5B7W2 3.05e-119 6 794 9 828
Beta-mannosidase B OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=mndB PE=1 SV=2
A1D911 6.28e-119 6 794 9 830
Beta-mannosidase B OS=Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) OX=331117 GN=mndB PE=3 SV=1
Q4WAH4 6.95e-117 6 794 9 830
Beta-mannosidase B OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=mndB PE=3 SV=1
B0YBU9 2.67e-116 6 794 9 830
Beta-mannosidase B OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) OX=451804 GN=mndB PE=3 SV=1
A2QYN2 7.48e-115 5 786 8 822
Beta-mannosidase B OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) OX=425011 GN=mndB PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000074 0.000003 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000004849_00738.