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CAZyme Information: MGYG000004867_01227
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | HGM11616 sp900761075 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; Christensenellaceae; HGM11616; HGM11616 sp900761075 | |||||||||||
| CAZyme ID | MGYG000004867_01227 | |||||||||||
| CAZy Family | GT39 | |||||||||||
| CAZyme Description | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 6169; End: 9936 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT39 | 840 | 1061 | 9.9e-53 | 0.9237668161434978 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam16192 | PMT_4TMC | 3.04e-16 | 1075 | 1236 | 4 | 185 | C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes. |
| COG5542 | COG5542 | 1.22e-15 | 281 | 582 | 81 | 369 | Mannosyltransferase related to Gpi18 [Carbohydrate transport and metabolism]. |
| pfam02366 | PMT | 3.27e-15 | 845 | 1060 | 22 | 239 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
| COG1928 | PMT1 | 8.77e-14 | 846 | 1059 | 50 | 265 | Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]. |
| pfam13231 | PMT_2 | 4.38e-13 | 869 | 1013 | 2 | 137 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AYH39702.1 | 2.51e-254 | 216 | 1252 | 19 | 1073 |
| QWT55655.1 | 2.12e-191 | 2 | 1251 | 3 | 1251 |
| QSF45552.1 | 6.74e-190 | 7 | 1251 | 11 | 1271 |
| ASA25569.1 | 9.28e-188 | 1 | 1251 | 5 | 1266 |
| AIQ39188.1 | 2.91e-183 | 8 | 1251 | 12 | 1277 |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| L8F4Z2 | 2.31e-25 | 846 | 1251 | 67 | 515 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1 |
| P9WN04 | 9.33e-20 | 846 | 1251 | 73 | 521 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2 |
| P9WN05 | 9.33e-20 | 846 | 1251 | 73 | 521 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2 |
| Q5ACU3 | 2.57e-07 | 1076 | 1254 | 520 | 719 | Dolichyl-phosphate-mannose--protein mannosyltransferase 5 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=PMT5 PE=2 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000333 | 0.998826 | 0.000237 | 0.000198 | 0.000189 | 0.000185 |
TMHMM Annotations download full data without filtering help
| start | end |
|---|---|
| 4 | 21 |
| 205 | 227 |
| 237 | 259 |
| 299 | 316 |
| 321 | 343 |
| 356 | 378 |
| 404 | 426 |
| 439 | 461 |
| 514 | 531 |
| 538 | 557 |
| 561 | 578 |
| 585 | 602 |
| 612 | 634 |
| 681 | 700 |
| 888 | 910 |
| 939 | 961 |
| 988 | 1010 |
| 1037 | 1059 |
| 1123 | 1145 |
| 1158 | 1175 |
| 1180 | 1199 |
| 1212 | 1234 |