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CAZyme Information: MGYG000004876_02718

You are here: Home > Sequence: MGYG000004876_02718

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides;
CAZyme ID MGYG000004876_02718
CAZy Family CBM50
CAZyme Description Integration host factor subunit alpha
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
415 MGYG000004876_41|CGC2 46300.41 4.2318
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004876 4781463 MAG China Asia
Gene Location Start: 25333;  End: 26580  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000004876_02718.

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam00216 Bac_DNA_binding 7.21e-19 10 93 5 88
Bacterial DNA-binding protein.
cd13832 IHF 1.96e-16 10 91 4 85
Integration host factor (IHF) and similar proteins. This subfamily includes integration host factor (IHF) and IHF-like domains. IHF is a nucleoid-associated protein (NAP) that binds and sharply bends many DNA targets in a sequence specific manner. It is a heterodimeric protein composed of two highly homologous subunits IHFA (IHF-alpha) and IHFB (IHF-beta). It is known to act as a transcription factor at many gene regulatory regions in E. coli. IHF is an essential cofactor in phage lambda site-specific recombination, having an architectural role during assembly of specialized nucleoprotein structures (snups). IHF is also involved in formation as well as maintenance of bacterial biofilms since it is found in complex with extracellular DNA (eDNA) within the extracellular polymeric substances (EPS) matrix of many biofilms. This subfamily also includes the protein Hbb from tick-borne spirochete Borrelia burgdorferi, responsible for causing Lyme disease in humans. Hbb, a homodimer, shows DNA sequence preferences that are related, yet distinct from those of IHF.
smart00411 BHL 6.77e-15 5 94 1 90
bacterial (prokaryotic) histone like domain.
cd13835 IHF_A 6.78e-15 10 93 5 88
Alpha subunit of integration host factor (IHFA). This subfamily consists of the alpha subunit of integration host factor (IHF) and IHF-like domains. IHF is a nucleoid-associated protein (NAP) that binds and sharply bends many DNA targets in a sequence specific manner. It is a heterodimeric protein composed of two highly homologous subunits IHFA (IHF-alpha) and IHFB (IHF-beta). It is known to act as a transcription factor at many gene regulatory regions in E. coli. IHF is an essential cofactor in phage lambda site-specific recombination, having an architectural role during assembly of specialized nucleoprotein structures (snups). IHF is also involved in formation as well as maintenance of bacterial biofilms since it is found in complex with extracellular DNA (eDNA) within the extracellular polymeric substances (EPS) matrix of many biofilms.
COG0776 HimA 9.13e-15 4 96 1 93
Bacterial nucleoid DNA-binding protein [Replication, recombination and repair].

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QUT91726.1 2.90e-137 1 415 1 471
QPH57227.1 4.50e-125 1 415 1 392
QBJ16968.1 4.50e-125 1 415 1 392
QMI81676.1 4.50e-125 1 415 1 392
QUT68036.1 7.29e-124 1 415 1 392

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5J0N_I 2.43e-09 12 93 9 90
ChainI, Integration host factor subunit alpha [Escherichia coli],5J0N_K Chain K, Integration host factor subunit alpha [Escherichia coli]
1IHF_A 2.62e-09 12 93 10 91
INTEGRATIONHOST FACTOR/DNA COMPLEX [Escherichia coli],1OUZ_A Chain A, Integration Host Factor Alpha-subunit [Escherichia coli],1OWF_A Chain A, Integration Host Factor Alpha-subunit [Escherichia coli],1OWG_A Crystal structure of WT IHF complexed with an altered H' site (T44A) [Escherichia coli],2HT0_A IHF bound to doubly nicked DNA [Escherichia coli],5WFE_K Cas1-Cas2-IHF-DNA holo-complex [Escherichia coli S88]
1HUE_A 1.86e-08 5 93 1 89
ChainA, HU PROTEIN [Geobacillus stearothermophilus],1HUE_B Chain B, HU PROTEIN [Geobacillus stearothermophilus],1HUU_A Dna-Binding Protein Hu From Bacillus Stearothermophilus [Geobacillus stearothermophilus],1HUU_B Dna-Binding Protein Hu From Bacillus Stearothermophilus [Geobacillus stearothermophilus],1HUU_C Dna-Binding Protein Hu From Bacillus Stearothermophilus [Geobacillus stearothermophilus]
5LVT_A 1.91e-08 6 93 3 90
Structureof HU protein from Lactococcus lactis [Lactococcus lactis subsp. lactis Il1403],5LVT_B Structure of HU protein from Lactococcus lactis [Lactococcus lactis subsp. lactis Il1403],5LVT_C Structure of HU protein from Lactococcus lactis [Lactococcus lactis subsp. lactis Il1403],5LVT_D Structure of HU protein from Lactococcus lactis [Lactococcus lactis subsp. lactis Il1403]
2IIE_A 2.00e-08 12 93 54 135
singlechain Integration Host Factor protein (scIHF2) in complex with DNA [Escherichia coli]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
B4UAP1 1.88e-10 9 108 5 104
Integration host factor subunit alpha OS=Anaeromyxobacter sp. (strain K) OX=447217 GN=ihfA PE=3 SV=1
B8J836 1.88e-10 9 108 5 104
Integration host factor subunit alpha OS=Anaeromyxobacter dehalogenans (strain 2CP-1 / ATCC BAA-258) OX=455488 GN=ihfA PE=3 SV=1
Q15SX9 4.52e-10 10 93 8 91
Integration host factor subunit alpha OS=Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087) OX=342610 GN=ihfA PE=3 SV=1
Q2IJA7 4.79e-10 9 94 5 90
Integration host factor subunit alpha OS=Anaeromyxobacter dehalogenans (strain 2CP-C) OX=290397 GN=ihfA PE=3 SV=1
Q21KD4 6.66e-10 1 90 1 90
Integration host factor subunit alpha OS=Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) OX=203122 GN=ihfA PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000055 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      download full data without filtering help

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