Basic Information | |
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Species | Selaginella moellendorffii |
Cazyme ID | 146424 |
Family | GT68 |
Protein Properties | Length: 368 Molecular Weight: 41448.6 Isoelectric Point: 7.2665 |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT68 | 66 | 345 | 0 |
DYSYEKTLDIAHIRSCLGEKTLLTFHEFLAKNKTDIRLLCYMSGCYLDEDHEKKIKALGLSWSSKTDAWPEEASLKGYPSHPRASEFVAKFSCEDEVLGI GDVFYSDVESQLVAQIGGPLQHSCKTIIRPNRLILLTAQRFVQTFLGSNFMALHFRRHGFLKFCNVKNESCFFPIPQAASCISRKIQEAKPRVIYVSTDA AESEITLLQQLLGPDVPMIQRPQHDSREKWDAILQRKGLLADNEVVAMLDKTIRAMAESFIGTPGSTFTDDIVRLRKEWG |
Full Sequence |
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Protein Sequence Length: 368 Download |
MGGCQGQNFS SRRHGKLVQW RPREDRFLLV ICTSGQISNH LICLEKHMFF AALLDRTLVL 60 PDPSVDYSYE KTLDIAHIRS CLGEKTLLTF HEFLAKNKTD IRLLCYMSGC YLDEDHEKKI 120 KALGLSWSSK TDAWPEEASL KGYPSHPRAS EFVAKFSCED EVLGIGDVFY SDVESQLVAQ 180 IGGPLQHSCK TIIRPNRLIL LTAQRFVQTF LGSNFMALHF RRHGFLKFCN VKNESCFFPI 240 PQAASCISRK IQEAKPRVIY VSTDAAESEI TLLQQLLGPD VPMIQRPQHD SREKWDAILQ 300 RKGLLADNEV VAMLDKTIRA MAESFIGTPG STFTDDIVRL RKEWGSSNSC DGVLCQGQHP 360 NFIADTD* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd11302 | O-FucT-1 | 0.003 | 48 | 342 | 363 | + GDP-fucose protein O-fucosyltransferase 1. The protein O-fucosyltransferase 1 (Ofut1 or O-FucT-1) adds O-fucose to EGF (epidermal growth factor-like) repeats. The O-fucsosylation of the Notch receptor signaling protein is dependent on this enzyme, which requires GDP-fucose as a substrate. O-fucose residues added to the target of O-FucT-1 may be further elongated by other glycosyltransferases. On top of O-fucosylation, O-FucT-1 may have other functions such as the regulation of the Notch receptor exit from the ER. Six highly conserved cysteines are present in O-FucT-1, which is a soluble ER protein, as well as a DXD-like motif (ERD), conserved in mammals, Drosophila, and C. elegans. Both features are characteristic of several glycosyltransferase families. The membrane-bound pre-protein is released by proteolysis and, as for most glycosyltransferases, is strongly activated by manganese. O-FucT-1 is similar to family 1 glycosyltransferases (GT1). | ||
cd11548 | NodZ_like | 0.002 | 193 | 334 | 144 | + Alpha 1,6-fucosyltransferase similar to Bradyrhizobium NodZ. Bradyrhizobium NodZ is an alpha 1,6-fucosyltransferase involved in the biosynthesis of the nodulation factor, a lipo-chitooligosaccharide formed by three-to-six beta-1,4-linked N-acetyl-d-glucosamine (GlcNAc) residues and a fatty acid acyl group attached to the nitrogen atom at the non-reducing end. NodZ transfers L-fucose from the GDP-beta-L-fucose donor to the reducing residue of the chitin oligosaccharide backbone, before the attachment of a fatty acid group. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
cd11296 | O-FucT_like | 8.0e-5 | 27 | 61 | 35 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
cd11298 | O-FucT-2 | 1.0e-7 | 211 | 334 | 124 | + GDP-fucose protein O-fucosyltransferase 2. O-FucT-2 adds O-fucose to thrombospondin type 1 repeats (TSRs), and appears conserved in bilateria. The O-fucosylation of TSRs appears to play a role in regulating secretion of metalloproteases of the ADAMTS superfamily. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
cd11296 | O-FucT_like | 5.0e-20 | 185 | 341 | 167 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. |
Sequence Alignments (This image is cropped. Click for full image.) |
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