Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000881647 |
Family | GT68 |
Protein Properties | Length: 585 Molecular Weight: 66267.8 Isoelectric Point: 7.062 |
Chromosome | Chromosome/Scaffold: 012044228 Start: 6222 End: 8862 |
Description | O-fucosyltransferase family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT68 | 263 | 556 | 0 |
NRVLVIPSPKVDYQFSRVLDIEHINKCLGRTVVVTFEELDEKKKNHVHIDKFICYFSHPTPCYVDDEHVKKLKGAGVSMNKLESAWVEDVKKPTKRTVQD VQSKFSSNDDVIAIGDVFFADLEQEWVMQARGPLAHKCKTLIEPSRLIMLTAQRFIQTFLGKNFVALHFRRHGFLKFCNNKQPSCFYPIPQAADCIIRVA ERANAPVVYLSTDAAESETGLLQSLVVVNGKTVPLVKRPARNSAEKWDALLYRQGIEGDAQVEAMLDKTICAMSSVFIGASGSTFTEDILRLRK |
Full Sequence |
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Protein Sequence Length: 585 Download |
MDRTSSSSSD DDDDRQNLID QNDRKLPTPR STAAAAFHIA DDDIDNNSNN RHYFHHQLRR 60 RFTSLKLGDL FNKRSFVLLA IFVPTFLVIL FFVTDMKSLL FTTGNFSSSP YDSASGKLLE 120 SELRALYLLK QQQVSLFNLW NXTLPNPTNS TSNHSDPXQI PLLDDFKSAV LRQISLNRDI 180 QQVLLSPHRT GNSTEPDFRD FGDFENPSLG DRCRAVDQQF SQRRTIEWKP NSNKYLFAIC 240 VSGQMSNHLI CLEKHMFFAA LLNRVLVIPS PKVDYQFSRV LDIEHINKCL GRTVVVTFEE 300 LDEKKKNHVH IDKFICYFSH PTPCYVDDEH VKKLKGAGVS MNKLESAWVE DVKKPTKRTV 360 QDVQSKFSSN DDVIAIGDVF FADLEQEWVM QARGPLAHKC KTLIEPSRLI MLTAQRFIQT 420 FLGKNFVALH FRRHGFLKFC NNKQPSCFYP IPQAADCIIR VAERANAPVV YLSTDAAESE 480 TGLLQSLVVV NGKTVPLVKR PARNSAEKWD ALLYRQGIEG DAQVEAMLDK TICAMSSVFI 540 GASGSTFTED ILRLRKDWGS ASLCDEYLCQ GEDPNFIAEN TTTS* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd11548 | NodZ_like | 0.004 | 401 | 556 | 162 | + Alpha 1,6-fucosyltransferase similar to Bradyrhizobium NodZ. Bradyrhizobium NodZ is an alpha 1,6-fucosyltransferase involved in the biosynthesis of the nodulation factor, a lipo-chitooligosaccharide formed by three-to-six beta-1,4-linked N-acetyl-d-glucosamine (GlcNAc) residues and a fatty acid acyl group attached to the nitrogen atom at the non-reducing end. NodZ transfers L-fucose from the GDP-beta-L-fucose donor to the reducing residue of the chitin oligosaccharide backbone, before the attachment of a fatty acid group. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
cd11296 | O-FucT_like | 3.0e-5 | 235 | 269 | 35 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
pfam10250 | O-FucT | 1.0e-6 | 258 | 548 | 332 | + GDP-fucose protein O-fucosyltransferase. This is a family of conserved proteins representing the enzyme responsible for adding O-fucose to EGF (epidermal growth factor-like) repeats. Six highly conserved cysteines are present in O-FucT-1 as well as a DXD-like motif (ERD), conserved in mammals, Drosophila, and C. elegans. Both features are characteristic of several glycosyltransferase families. The enzyme is a membrane-bound protein released by proteolysis and, as for most glycosyltransferases, is strongly activated by manganese. | ||
cd11298 | O-FucT-2 | 2.0e-7 | 408 | 548 | 145 | + GDP-fucose protein O-fucosyltransferase 2. O-FucT-2 adds O-fucose to thrombospondin type 1 repeats (TSRs), and appears conserved in bilateria. The O-fucosylation of TSRs appears to play a role in regulating secretion of metalloproteases of the ADAMTS superfamily. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
cd11296 | O-FucT_like | 1.0e-17 | 396 | 555 | 170 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAM66093.1 | 0 | 7 | 580 | 4 | 565 | unknown [Arabidopsis thaliana] |
RefSeq | NP_173170.2 | 0 | 7 | 580 | 4 | 563 | unknown protein [Arabidopsis thaliana] |
RefSeq | NP_199853.1 | 0 | 7 | 580 | 4 | 565 | unknown protein [Arabidopsis thaliana] |
RefSeq | XP_002264087.1 | 0 | 8 | 580 | 5 | 558 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002303337.1 | 0 | 112 | 580 | 64 | 526 | predicted protein [Populus trichocarpa] |