Basic Information | |
---|---|
Species | Brachypodium distachyon |
Cazyme ID | Bradi4g18970.1 |
Family | AA7 |
Protein Properties | Length: 531 Molecular Weight: 57055.9 Isoelectric Point: 6.769 |
Chromosome | Chromosome/Scaffold: 4 Start: 21551937 End: 21553682 |
Description | FAD-binding Berberine family protein |
View CDS |
External Links |
---|
NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
AA7 | 65 | 525 | 0 |
NTTARPSCIVTATAAPHVQDAVRCGRLHGVRLRVRSGGHDFEGLSYRSVRDDGQSFAVLDLARLRAVSISRGSWWEAATAWVDSGATLGELYYAIGKASP TLAFPGGACPTVGVGGFLSGGGIGLMTRKYGIGTDSVVDARVVNADGELLDRGSMGEDLFWAIRGGGGESFGVVVSWRLKLSSMVSPTVTVFNIGKTFDE SSTAAVLAKWETLALDQSLPDELTIRVALQGKNVFFQALFLGGCTRLEYTMRRLLPELGMSSADCREMSWLRAMSFISLGSMDTPVEAMLNRTNNLGTYV KNRSDYVRRAVGKAGWESISREHLSPSGGAVLMILEPHGGAVARVSADSTPYPHRAGVLYNVQYAVYWCCDADGGAAAAATGRLDGLYGFMEPMVSSNPR EAFANYRDLDIGQNAVGADGLTAYESGRVWGERYFMGNFRRLAAVKGKVDPGDYFRNEQSI |
Full Sequence |
---|
Protein Sequence Length: 531 Download |
MAVSPVLLAL VLIVFFPTLT SCSPADEFIQ CLSEKIPSEL LYPQNSTGFM SVLSSSVQNP 60 KFLTNTTARP SCIVTATAAP HVQDAVRCGR LHGVRLRVRS GGHDFEGLSY RSVRDDGQSF 120 AVLDLARLRA VSISRGSWWE AATAWVDSGA TLGELYYAIG KASPTLAFPG GACPTVGVGG 180 FLSGGGIGLM TRKYGIGTDS VVDARVVNAD GELLDRGSMG EDLFWAIRGG GGESFGVVVS 240 WRLKLSSMVS PTVTVFNIGK TFDESSTAAV LAKWETLALD QSLPDELTIR VALQGKNVFF 300 QALFLGGCTR LEYTMRRLLP ELGMSSADCR EMSWLRAMSF ISLGSMDTPV EAMLNRTNNL 360 GTYVKNRSDY VRRAVGKAGW ESISREHLSP SGGAVLMILE PHGGAVARVS ADSTPYPHRA 420 GVLYNVQYAV YWCCDADGGA AAAATGRLDG LYGFMEPMVS SNPREAFANY RDLDIGQNAV 480 GADGLTAYES GRVWGERYFM GNFRRLAAVK GKVDPGDYFR NEQSIPPLLQ * 540 |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
COG0277 | GlcD | 3.0e-13 | 67 | 322 | 263 | + FAD/FMN-containing dehydrogenases [Energy production and conversion] | ||
pfam08031 | BBE | 6.0e-15 | 466 | 526 | 61 | + Berberine and berberine like. This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine. | ||
pfam01565 | FAD_binding_4 | 2.0e-18 | 70 | 217 | 149 | + FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidises the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0008762 | UDP-N-acetylmuramate dehydrogenase activity |
GO:0016491 | oxidoreductase activity |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABA93766.1 | 0 | 6 | 530 | 10 | 538 | Reticuline oxidase precursor, putative [Oryza sativa (japonica cultivar-group)] |
GenBank | EAY80999.1 | 0 | 6 | 530 | 10 | 538 | hypothetical protein OsI_36182 [Oryza sativa Indica Group] |
GenBank | EAZ01289.1 | 0 | 19 | 529 | 26 | 523 | hypothetical protein OsI_23318 [Oryza sativa Indica Group] |
RefSeq | NP_001057831.1 | 0 | 19 | 529 | 26 | 523 | Os06g0549600 [Oryza sativa (japonica cultivar-group)] |
RefSeq | NP_001067934.1 | 0 | 6 | 492 | 10 | 500 | Os11g0495700 [Oryza sativa (japonica cultivar-group)] |
Annotations - PDB Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 4dns_B | 0 | 27 | 529 | 12 | 497 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
PDB | 4dns_A | 0 | 27 | 529 | 12 | 497 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
PDB | 3tsj_B | 0 | 26 | 530 | 9 | 498 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
PDB | 3tsj_A | 0 | 26 | 530 | 9 | 498 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
PDB | 3tsh_A | 0 | 26 | 530 | 9 | 498 | A Chain A, Crystal Structure Of Phl P 4, A Grass Pollen Allergen With Glucose Dehydrogenase Activity |
Metabolic Pathways | |||
---|---|---|---|
Pathway Name | Reaction | EC | Protein Name |
cannabinoid biosynthesis | RXN-7854 | EC-1.21.3 | tetrahydrocannabinolic acid synthase |