Basic Information | |
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Species | Panicum virgatum |
Cazyme ID | Pavirv00019442m |
Family | AA7 |
Protein Properties | Length: 372 Molecular Weight: 41325.5 Isoelectric Point: 5.0193 |
Chromosome | Chromosome/Scaffold: 0283538 Start: 87 End: 1202 |
Description | FAD-binding Berberine family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA7 | 3 | 342 | 4.1e-40 |
LAGDNVVDAVLVDAEGRVLDRASMGEDVFWAIRGGGGGAWGAVYAWRVQLRPVPERVTAFVVNRPGTAASVARLVSTWQHVAPWLPDEFYISAFVGAGLP ESNGTGISVTFKGFYLGPADEALQILTARLPEIGLSDLNPREMSWIESVVFFSGLPEGSSVSDLTDRVLHKKNYFKAKSDYARRPMALDQLIRAVDLLSE QPRAYVILDPYGGAMDRIDPADLPFPHRKGNIHGIQYLIEWAADEDGHRDEYMDWLRRFYDFMGAYVAKNPRAAYINYMDLDLGTNNWSDDRQPDNKIPN PEVEAARAWGERYFLGNYDRLVRAKTTIDPDNVFRNAQSI |
Full Sequence |
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Protein Sequence Length: 372 Download |
ARLAGDNVVD AVLVDAEGRV LDRASMGEDV FWAIRGGGGG AWGAVYAWRV QLRPVPERVT 60 AFVVNRPGTA ASVARLVSTW QHVAPWLPDE FYISAFVGAG LPESNGTGIS VTFKGFYLGP 120 ADEALQILTA RLPEIGLSDL NPREMSWIES VVFFSGLPEG SSVSDLTDRV LHKKNYFKAK 180 SDYARRPMAL DQLIRAVDLL SEQPRAYVIL DPYGGAMDRI DPADLPFPHR KGNIHGIQYL 240 IEWAADEDGH RDEYMDWLRR FYDFMGAYVA KNPRAAYINY MDLDLGTNNW SDDRQPDNKI 300 PNPEVEAARA WGERYFLGNY DRLVRAKTTI DPDNVFRNAQ SIPPLRVPGV TRSSPRGISP 360 EVISNGSTYD S* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
COG0277 | GlcD | 4.0e-5 | 1 | 345 | 362 | + FAD/FMN-containing dehydrogenases [Energy production and conversion] | ||
pfam08031 | BBE | 6.0e-16 | 276 | 343 | 68 | + Berberine and berberine like. This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine. |
Gene Ontology | |
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GO Term | Description |
GO:0016491 | oxidoreductase activity |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAC65012.1 | 0 | 3 | 371 | 194 | 562 | putative berberine bridge enzyme [Oryza sativa Japonica Group] |
GenBank | EAZ05661.1 | 0 | 3 | 371 | 194 | 562 | hypothetical protein OsI_27888 [Oryza sativa Indica Group] |
GenBank | EAZ41578.1 | 0 | 51 | 371 | 42 | 362 | hypothetical protein OsJ_26112 [Oryza sativa Japonica Group] |
RefSeq | XP_002445090.1 | 0 | 3 | 371 | 200 | 512 | hypothetical protein SORBIDRAFT_07g003960 [Sorghum bicolor] |
RefSeq | XP_002533924.1 | 0 | 3 | 350 | 197 | 540 | d-lactate dehydrogenase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3fw9_A | 0 | 3 | 345 | 164 | 494 | A Chain A, Structure Of Berberine Bridge Enzyme In Complex With (S)-Scoulerine |
PDB | 3fw8_A | 0 | 3 | 345 | 164 | 494 | A Chain A, Structure Of Berberine Bridge Enzyme, C166a Variant |
PDB | 3fwa_A | 0 | 3 | 345 | 164 | 494 | A Chain A, Structure Of Berberine Bridge Enzyme, C166a Variant In Complex With (S)-Reticuline |
PDB | 3fw7_A | 0 | 3 | 345 | 167 | 497 | A Chain A, Structure Of Berberine Bridge Enzyme, H104a Variant |
PDB | 3d2j_A | 0 | 3 | 345 | 189 | 519 | A Chain A, Structure Of Berberine Bridge Enzyme, H104a Variant |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
berberine biosynthesis | RETICULINE-OXIDASE-RXN | EC-1.21.3.3 | reticuline oxidase |
dehydroscoulerine biosynthesis | RETICULINE-OXIDASE-RXN | EC-1.21.3.3 | reticuline oxidase |
sanguinarine and macarpine biosynthesis | RETICULINE-OXIDASE-RXN | EC-1.21.3.3 | reticuline oxidase |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
EL451713 | 298 | 51 | 347 | 0 |
GO028240 | 277 | 69 | 345 | 0 |
ES434378 | 248 | 3 | 250 | 0 |
EB740763 | 302 | 45 | 345 | 0 |
HO781153 | 350 | 3 | 345 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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