| Basic Information | |
|---|---|
| Species | Carica papaya |
| Cazyme ID | evm.model.supercontig_51.46 |
| Family | GT41 |
| Protein Properties | Length: 755 Molecular Weight: 85352.8 Isoelectric Point: 7.0631 |
| Chromosome | Chromosome/Scaffold: 51 Start: 528106 End: 536700 |
| Description | Tetratricopeptide repeat (TPR)-like superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT41 | 234 | 522 | 0 |
| RPTMAEAHANLASAYKDSGHVEAAIKSYKQALLLRPDFPEATCNLLHTLQCVCCWDDRDNMFAEVEGIIRRQINMSVLPSVQPFHAIAYPIDPILALEIS RKYAAHCSIVASRFQLPRFNHPAPVPVKRDGGFERLRVGYVSSDFGNHPLSHLMGSVFGMHNKENVEVFCYALSQNDGTEWRQRIQSEAEHFIDVSAMTS DVIAKMINEDKIQILVNLNGYTKGARNEIFAMQPAPIQVSYMGFPGTTGATYIDYLVTDEFVSPLRYAHIYSEKLVHLPHCYFVNDYKQ | |||
| GT41 | 533 | 743 | 0 |
| QHKRSDYGLPEDKFIFACFNQLYKMDPEVFNTWCNILKRVPNSALWLLRFPAAGEMRLRQYAVAQGVHPEQIIFTDVAMKHEHIRRSALADLFLDTPLCN AHTTGTDILWAGLPMVTLPLEKMATRVAGSLCLATGLGEEMIVSSMKEYEEKAVSLALNRPKLQALTNRLKAGRMTCPLFDTARWVRNLERSYFKMWNLH CSGQQLQHFKV | |||
| Full Sequence |
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| Protein Sequence Length: 755 Download |
| MMISLQSGAG VSRAPFISDR AEDAFAVKAE PSSALSLQPF KGHDSHEVDE DMHLALAHQM 60 YKAGNYKQAL EHSIAIYERS SLRTDISSPW SNILSARNEE ALRIEPRFAE CYGNMANAWK 120 EKGDIDLAIR YYLVAIELRP NFADAWSNLA SAYMRKGRLN EAAQCCRQAL QLNPLLVDAH 180 SNLGNLMKAQ GLIQEVLRIE PLAADGLVNR GNTYKEVGRV SEAIQDYIRA INIRPTMAEA 240 HANLASAYKD SGHVEAAIKS YKQALLLRPD FPEATCNLLH TLQCVCCWDD RDNMFAEVEG 300 IIRRQINMSV LPSVQPFHAI AYPIDPILAL EISRKYAAHC SIVASRFQLP RFNHPAPVPV 360 KRDGGFERLR VGYVSSDFGN HPLSHLMGSV FGMHNKENVE VFCYALSQND GTEWRQRIQS 420 EAEHFIDVSA MTSDVIAKMI NEDKIQILVN LNGYTKGARN EIFAMQPAPI QVSYMGFPGT 480 TGATYIDYLV TDEFVSPLRY AHIYSEKLVH LPHCYFVNDY KQKNRDVLDP KCQHKRSDYG 540 LPEDKFIFAC FNQLYKMDPE VFNTWCNILK RVPNSALWLL RFPAAGEMRL RQYAVAQGVH 600 PEQIIFTDVA MKHEHIRRSA LADLFLDTPL CNAHTTGTDI LWAGLPMVTL PLEKMATRVA 660 GSLCLATGLG EEMIVSSMKE YEEKAVSLAL NRPKLQALTN RLKAGRMTCP LFDTARWVRN 720 LERSYFKMWN LHCSGQQLQH FKVTENDMEF PYDR* |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| cd00189 | TPR | 1.0e-15 | 54 | 174 | 121 | + Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans in various subcellular locations; involved in a variety of functions including protein-protein interactions, but common features in the interaction partners have not been defined; involved in chaperone, cell-cycle, transciption, and protein transport complexes; the number of TPR motifs varies among proteins (1,3-11,13 15,16,19); 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accomodate an alpha-helix of a target protein; it has been proposed that TPR proteins preferably interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes; examples of TPR-proteins include, Cdc16p, Cdc23p and Cdc27p components of the cyclosome/APC, the Pex5p/Pas10p receptor for peroxisomal targeting signals, the Tom70p co-receptor for mitochondrial targeting signals, Ser/Thr phosphatase 5C and the p110 subunit of O-GlcNAc transferase; three copies of the repeat are present here |
| cd00189 | TPR | 2.0e-19 | 110 | 201 | 99 | + Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans in various subcellular locations; involved in a variety of functions including protein-protein interactions, but common features in the interaction partners have not been defined; involved in chaperone, cell-cycle, transciption, and protein transport complexes; the number of TPR motifs varies among proteins (1,3-11,13 15,16,19); 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accomodate an alpha-helix of a target protein; it has been proposed that TPR proteins preferably interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes; examples of TPR-proteins include, Cdc16p, Cdc23p and Cdc27p components of the cyclosome/APC, the Pex5p/Pas10p receptor for peroxisomal targeting signals, the Tom70p co-receptor for mitochondrial targeting signals, Ser/Thr phosphatase 5C and the p110 subunit of O-GlcNAc transferase; three copies of the repeat are present here |
| pfam13844 | Glyco_transf_41 | 5.0e-73 | 369 | 538 | 176 | + Glycosyl transferase family 41. This family of glycosyltransferases includes O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase, an enzyme which catalyzes the addition of O-GlcNAc to serine and threonine residues. In addition to its function as an O-GlcNAc transferase, human OGT, also appears to proteolytically cleave the epigenetic cell-cycle regulator HCF-1. |
| pfam13844 | Glyco_transf_41 | 4.0e-74 | 536 | 729 | 194 | + Glycosyl transferase family 41. This family of glycosyltransferases includes O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase, an enzyme which catalyzes the addition of O-GlcNAc to serine and threonine residues. In addition to its function as an O-GlcNAc transferase, human OGT, also appears to proteolytically cleave the epigenetic cell-cycle regulator HCF-1. |
| COG3914 | Spy | 5.0e-104 | 157 | 730 | 586 | + Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones] |
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005515 | protein binding |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_002270163.1 | 0 | 1 | 281 | 1 | 309 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002270163.1 | 0 | 99 | 754 | 290 | 986 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002270163.1 | 5e-21 | 100 | 278 | 223 | 374 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002325368.1 | 0 | 64 | 754 | 160 | 873 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002325368.1 | 0 | 96 | 281 | 4 | 196 | predicted protein [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 4gz6_D | 0 | 106 | 531 | 6 | 406 | X Chain X, Crystal Structure Of The Full-Length Autotransporter Esta From Pseudomonas Aeruginosa |
| PDB | 4gz6_D | 0 | 536 | 741 | 514 | 718 | X Chain X, Crystal Structure Of The Full-Length Autotransporter Esta From Pseudomonas Aeruginosa |
| PDB | 4gz6_D | 0.00000000000005 | 99 | 188 | 67 | 156 | X Chain X, Crystal Structure Of The Full-Length Autotransporter Esta From Pseudomonas Aeruginosa |
| PDB | 4gz6_C | 0 | 106 | 531 | 6 | 406 | X Chain X, Crystal Structure Of The Full-Length Autotransporter Esta From Pseudomonas Aeruginosa |
| PDB | 4gz6_C | 0 | 536 | 741 | 514 | 718 | X Chain X, Crystal Structure Of The Full-Length Autotransporter Esta From Pseudomonas Aeruginosa |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO795247 | 461 | 295 | 755 | 0 |
| HO778725 | 450 | 306 | 755 | 0 |
| GT034150 | 327 | 402 | 728 | 0 |
| GO881553 | 320 | 370 | 689 | 0 |
| HO795247 | 52 | 243 | 294 | 1e-20 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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