Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.004G064600.2 |
Family | GT20 |
Protein Properties | Length: 709 Molecular Weight: 80201.6 Isoelectric Point: 6.6668 |
Chromosome | Chromosome/Scaffold: 04 Start: 5364752 End: 5376465 |
Description | trehalose-6-phosphate synthase |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT20 | 1 | 341 | 0 |
MFADVVHEHYEEGDVVWCHDYHLMFLPRCLKEKNSNIKVGWFLHTPFPSSEIHRMLPSRRDLLESVLAADLVGFHTYDYARHFVSACTRILGLEGTPEGV ENQGKLTRVAAFPIGIDSDRFIRALELPQVQDHIKELKERFAGRKVMLGVDRLDMIKGIPQKILAFEEFLEENPEWRDKVVLLQIAVPTRTDVPEYQKLS SQVHEIVGRINGRFGTLTAVPIHHLDRSLDFHALCALYAVTDVALITSLRDGMNLVSYEFVACQASKKGVLILSEFAGAAQSLGAGALLVNPWNIAEVAA SISQALNMPADEREKMHQHNFMHVTTHTSQEWAATFVSELN |
Full Sequence |
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Protein Sequence Length: 709 Download |
MFADVVHEHY EEGDVVWCHD YHLMFLPRCL KEKNSNIKVG WFLHTPFPSS EIHRMLPSRR 60 DLLESVLAAD LVGFHTYDYA RHFVSACTRI LGLEGTPEGV ENQGKLTRVA AFPIGIDSDR 120 FIRALELPQV QDHIKELKER FAGRKVMLGV DRLDMIKGIP QKILAFEEFL EENPEWRDKV 180 VLLQIAVPTR TDVPEYQKLS SQVHEIVGRI NGRFGTLTAV PIHHLDRSLD FHALCALYAV 240 TDVALITSLR DGMNLVSYEF VACQASKKGV LILSEFAGAA QSLGAGALLV NPWNIAEVAA 300 SISQALNMPA DEREKMHQHN FMHVTTHTSQ EWAATFVSEL NDTIIEAQLR TRQVPLLPVK 360 VAVERYLQSN NRLLMLGFNA TLTEPANTQG VRGGHIRELQ SRLHPEIKET LKKLCDDRRT 420 NIVILSGSDR AVLDDNFREY NLWLAAENGM FLRHSTGEWM TTMPENLNMD WVDSVKHVFE 480 YFTERTPGSH FELRETSLVW KYKYAESHFG KLQSKDMLQH LWTGPISNAA VDVVQGDRSV 540 EVRSVGVTKG AAIDRILGEI VRNKGMKSPI DYVLCAGHFL SKDEDVYTFF EPELPCESLA 600 LARTRSLDPA RTSISMIPDS TNQVKAHQLR KQRSLSTLER SNYRSAAWRP IVHDRMSLPE 660 GSSVLDLKAE NFFSCTVSRK QSEARYLLQS SDDVVTLLKE LAESKSPN* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PLN03064 | PLN03064 | 0 | 1 | 708 | 714 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PLN03063 | PLN03063 | 0 | 1 | 702 | 703 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PRK14501 | PRK14501 | 0 | 2 | 577 | 577 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
TIGR02400 | trehalose_OtsA | 0 | 1 | 342 | 342 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming]. This enzyme catalyzes the key, penultimate step in biosynthesis of trehalose, a compatible solute made as an osmoprotectant in some species in all three domains of life. The gene symbol OtsA stands for osmotically regulated trehalose synthesis A. Trehalose helps protect against both osmotic and thermal stresses, and is made from two glucose subunits. This model excludes glucosylglycerol-phosphate synthase, an enzyme of an analogous osmoprotectant system in many cyanobacterial strains. This model does not identify archaeal examples, as they are more divergent than glucosylglycerol-phosphate synthase. Sequences that score in the gray zone between the trusted and noise cutoffs include a number of yeast multidomain proteins in which the N-terminal domain may be functionally equivalent to this family. The gray zone also includes the OtsA of Cornyebacterium glutamicum (and related species), shown to be responsible for synthesis of only trace amounts of trehalose while the majority is synthesized by the TreYZ pathway; the significance of OtsA in this species is unclear (see Wolf, et al., PMID:12890033) [Cellular processes, Adaptations to atypical conditions]. |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005992 | trehalose biosynthetic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABO61742.1 | 0 | 1 | 708 | 217 | 923 | trehalose-phosphate synthase 1 [Solanum lycopersicum] |
RefSeq | XP_002305707.1 | 0 | 1 | 708 | 192 | 899 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002331300.1 | 0 | 1 | 706 | 213 | 922 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002522296.1 | 0 | 1 | 706 | 208 | 913 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
RefSeq | XP_002531237.1 | 0 | 1 | 706 | 216 | 924 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1uqu_B | 0 | 11 | 364 | 122 | 476 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
PDB | 1uqu_A | 0 | 11 | 364 | 122 | 476 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
PDB | 1uqt_B | 0 | 11 | 364 | 122 | 476 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
PDB | 1uqt_A | 0 | 11 | 364 | 122 | 476 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
PDB | 2wtx_D | 0 | 11 | 352 | 122 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
ES813375 | 361 | 237 | 596 | 0 |
EL390904 | 268 | 79 | 346 | 0 |
CX545499 | 305 | 179 | 482 | 0 |
DW069910 | 249 | 1 | 249 | 0 |
DV705833 | 283 | 309 | 590 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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