| AD families | AD genes | Defense system | CLAN ID | Phages/MGEs | References | Description |
|---|---|---|---|---|---|---|
| APIS094 | Rad | Retron | CLAN037 | Escherichia phage SP15 | Azam et al., 2023 | Rad inhibited retron function by degrading noncoding RNA, the precursor of msDNA. |
| APIS116 | CLAN037 | |||||
| APIS130 | RacC | Retron | CLAN054 | prophage of Escherichia coli str. K-12 substr. MG1655 | PMID:35850148 | RacC is a Rac prophage gene, function as retron TA blocker. It directly blocks RcaT toxicity, inhibit the toxin of abortive infection systems. |
| APIS142 | CLAN037 | |||||
| APIS191 | CLAN037 |