Browse anti-prokaryotic immune system families by Defense system

AD families AD genes Defense system CLAN ID Phages/MGEs References Description
APIS027 DSAD1 defence-associated sirtuin (DSR) CLAN038 SPbeta phages of B. subtilis PMID:36192536 DSAD1 is a phage anti-DSR2 protein that binds and inhibits Defence-associated sirtuins (DSR2). In bacteria, N-terminal sirtuin (SIR2) domains within DSR2 were shown to participate in defence systems including prokaryotic argonautes (pAgo), Thoeris, AVAST, defence-associated sirtuin (DSR), etc.