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Seed proteins  | Seed protein 3D structures  |  Structural homologs  |  Family infomation  | Homology to other families  | Family members, sources, and their hosts  

Seed protein information help

APIS family ID APIS033
Inhibited defense system restriction-modification (RM)
CLAN ID CLAN007
Seed protein property
Accession ID Gene name Protein length Molecular weight Isoelectric point Charge
YP_009168126.1 gene_page: Lar 78 8484.49 4.9995 -1
Phage property
Phage Assembly id
Escherichia phage vB_EcoP_24B GCF_001308415.1
PMID/References PMID:7476171
PDB structures ;
Pfam domains PF14354.9
Phrog phrog_6422,phrog_599
Host taxa d__Bacteria;p__Proteobacteria;c__Gammaproteobacteria;o__Enterobacterales;f__Enterobacteriaceae;g__Escherichia;s__Escherichia coli
Gene Location Start: ;  End: ;  Strand: 
Description Lar is functionally similar to RaI, is able to alleviate restriction and enhance modification by EcoKI. And the nucleotide sequences of their genes share 47% identity, indicating a common origin.

Predicted 3D structure by alphafold2 with pTM = 0.55 Download help

pTM is for the estimate of the TM-score, which is obtained from a pairwise error prediction. The higher pTM score indicates better model quality.

pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .

Residues were colored according to plddt ( blue-> high quality; red-> low quality ).

Full Sequence
90 < plddt <=100 ;
70 < plddt <= 90 ;
50 < plddt <= 70 ;
0 <= plddt <= 50 ;      Download help

Structural homologs

No homologs found in AlphaFold database

No homologs found in esmfold database

Family information      Download help

Fam ID Seed protein Member count Model Alignment
APIS033 YP_009168126.1 11 HMM model Member alignment

Host Taxa distribution

Length distribution

Homology to other families       download full data without filtering help

Clan ID: CLAN007

Hit APIS family E-Value Query Start Query End Hit Start Hit End Immune system Seed protein
APIS040 3.12E-41 1 72 72 142 IMGVR_UViG_2778261704_000001|2778261704|2781089226

Family members, sources, and their hosts        help

Results of representative protein blast against members.

Member pident evalue bitscore qcovs phage host SourceDB Pfam Phrog
AP012540_00031 98.718 7.27e-49 157 100% Stx2-converting phage Stx2a_WGPS8 INPHARED PF14354 phrog_6422 phrog_599
IMGVR_UViG_2519899562_000006|2519899562|2520131485 100.000 3.81e-50 160 100% Escherichia coli IMGVR PF14354 phrog_6422 phrog_599
IMGVR_UViG_2529292885_000005|2529292885|2530372492 97.436 1.34e-48 156 100% Escherichia coli IMGVR PF14354 phrog_6422 phrog_599
IMGVR_UViG_2529293213_000020|2529293213|2531600772 98.718 1.46e-49 158 100% Escherichia coli IMGVR PF14354 phrog_6422 phrog_599
IMGVR_UViG_2551306491_000008|2551306491|2553288095 97.222 1.03e-43 144 92% Escherichia coli IMGVR PF14354 phrog_6422 phrog_599
IMGVR_UViG_2558860471_000005|2558860471|2560001167 50.000 3.72e-14 69.3 88% Salmonella enterica IMGVR PF14354 phrog_19812 phrog_599
IMGVR_UViG_2713896907_000004|2713896907|2714825659 97.436 2.97e-48 155 100% Escherichia albertii IMGVR PF14354 phrog_6422 phrog_599
IMGVR_UViG_3300029722_000051|3300029722|Ga0245188_10156010 98.718 1.81e-48 155 100% Enterobacteriaceae IMGVR PF14354 phrog_6422 phrog_599
JQ347801_00035 98.718 2.48e-49 158 100% Escherichia phage JLK-2012 Escherichia INPHARED PF14354 phrog_6422 phrog_599
OP797663_00040 97.436 1.85e-48 155 100% Escherichia phage 06-3462 Escherichia INPHARED PF14354 phrog_6422 phrog_599
YP_009168126.1 100.000 1.48e-56 159 100% Escherichia phage vB_EcoP_24B Escherichia coli NCBI PF14354 phrog_6422 phrog_599
APIS Contig Range
APIS033 NC_027984.1 -

Gene cluster comparison plot by clinker      Download html