dbAPIS: a database of anti-prokaryotic immune systems

Seed protein information help

APIS family ID

APIS125

Inhibited defense system

toxin-antitoxin (TA)

CLAN ID

CLAN052

Seed protein property

Accession ID	Gene name	Protein length	Molecular weight	Isoelectric point	Charge
YP_009986712.1	gene_page: U56	180	21504.66	7.7955	3.5

Phage property

Phage	Assembly id
Escherichia phage Ukendt	GCF_010121085.1

PMID/References

PMID:38788717

PDB structures

8BAU;

Pfam domains

PF08719.16,PF08719.16

Phrog

phrog_1017,phrog_1017

Host taxa

d__Bacteria;p__Proteobacteria;c__Gammaproteobacteria;o__Enterobacterales;f__Enterobacteriaceae;g__Escherichia;

Gene Location

Start: 26712; End: 27254; Strand: +

Description

Retron-Eco1 inhibitor

Seed genomic context Download table help

Genome accession	Start	End	Strand	Protein ID	Length	Molecular weight	Charge	Isoelectric point	Function	Phrog	PFAM
NC_052661.1	23418	23774	+	YP_009986707.1	118	13157.31	3.0	8.8972	hypothetical protein	phrog_5474
NC_052661.1	23774	24913	+	YP_009986708.1	379	42143.12	-6.5	5.0234	ATPase	phrog_2376	PF00004.34
NC_052661.1	24955	26163	+	YP_009986709.1	402	45771.13	15.5	8.3428	endonuclease		PF21817.2
NC_052661.1	26157	26522	+	YP_009986710.1	121	14609.63	-8.0	4.4901	hypothetical protein	phrog_24465
NC_052661.1	26536	26715	+	YP_009986711.1	59	6947.12	-1.0	5.6713	hypothetical protein	phrog_22330
NC_052661.1	26712	27254	+	YP_009986712.1	180	21504.66	3.5	7.7955	hypothetical protein	phrog_1017 ; phrog_1017	PF08719.16 ;PF08719.16
NC_052661.1	28516	28713	+	YP_009986713.1	65	7148.11	-3.0	4.8978	hypothetical protein	phrog_23268
NC_052661.1	28806	29078	+	YP_009986714.1	90	9764.28	3.0	9.5285	hypothetical protein	phrog_8099
NC_052661.1	29155	29412	+	YP_009986715.1	85	10054.78	9.5	9.9611	hypothetical protein	phrog_17947
NC_052661.1	29414	29971	+	YP_009986716.1	185	20884.08	-17.5	4.1466	hypothetical protein	phrog_16605
NC_052661.1	30054	30149	+	YP_009986717.1	31	3386.14	0.0	5.8613	hypothetical protein

Seed genomic context- JBrowse

PDB structure: 8BAU ; Download help

Full Sequence Download help

Structural homologs

Structure homologs against by afdb (html) ; download full result table

Hit	Query start	Query end	Hit start	Hit end	TMscore(ali)	TMscore(avg)
AF-Q9HVK4-F1-model_v4	5	171	20	184	0.8557	0.8207
AF-O61936-F1-model_v4	1	178	3	193	0.8807	0.8166
AF-K0F6K4-F1-model_v4	5	172	19	184	0.8468	0.8067
AF-A0A0N4UI13-F1-model_v4	1	179	5	189	0.8503	0.8038
AF-O16327-F1-model_v4	1	179	3	200	0.8748	0.7993
AF-C0NGJ7-F1-model_v4	3	174	4	181	0.8422	0.7967
AF-G5EFJ3-F1-model_v4	1	176	3	196	0.8604	0.79
AF-Q54TQ0-F1-model_v4	4	174	3	151	0.8661	0.7878
AF-Q54QD6-F1-model_v4	4	174	4	153	0.8536	0.7796
AF-P30176-F1-model_v4	3	172	11	159	0.8265	0.7675

Structure homologs against by esmdb (html) ; download full result table

Hit	Query start	Query end	Hit start	Hit end	TMscore(ali)	TMscore(avg)
MGYP003483112803.pdb	1	170	1	158	0.9745	0.9093
MGYP003609360230.pdb	1	172	1	160	0.9632	0.9062
MGYP000633220123.pdb	1	171	2	159	0.9676	0.9054
MGYP000010601968.pdb	1	170	1	157	0.9733	0.9053
MGYP003376865982.pdb	4	174	1	160	0.9638	0.9048
MGYP003876978335.pdb	1	173	1	164	0.9528	0.9047
MGYP001814629545.pdb	1	174	1	162	0.9597	0.9046
MGYP003613875942.pdb	7	173	1	157	0.9713	0.9045
MGYP001667813869.pdb	1	169	1	156	0.9746	0.9042
MGYP001114870296.pdb	1	171	1	160	0.9636	0.9034

Family information Download help

Fam ID	Seed protein	Member count	Model	Alignment
APIS125	YP_009986712.1	81	HMM model	Member alignment

Host Taxa distribution

Length distribution

Homology to other families help

Clan ID: CLAN052

APIS125 has no similar APIS family.

Family members, sources, and their hosts help

Results of representative protein blast against members.
Member	pident	evalue	bitscore	qcovs	phage	host	SourceDB	Pfam	Phrog
IMGVR_UViG_3300045971_000577\|3300045971\|Ga0485188_0000017_228187_228663	36.600	2.108E-28	110	0.978%			IMGVR	PF08719	phrog_1017
IMGVR_UViG_3300049491_000383\|3300049491\|Ga0499963_000018_78505_78987	37.400	1.381E-27	108	0.928%			IMGVR	PF08719	phrog_1017
IMGVR_UViG_3300037487_001316\|3300037487\|Ga0393275_0000003_33270_33749	38.300	1.237E-26	105	0.872%			IMGVR	PF08719	phrog_1017
IMGVR_UViG_3300022468_000500\|3300022468\|Ga0233289_1426434853	36.800	4.834E-27	106	0.933%			IMGVR	PF08719	phrog_1017
IMGVR_UViG_3300037466_002980\|3300037466\|Ga0395898_0000033_129922_130410	36.800	9.043E-27	105	0.928%			IMGVR	PF08719	phrog_1017
IMGVR_UViG_3300020045_006153\|3300020045\|Ga0206662_1000002279	39.100	7.382E-28	108	0.878%			IMGVR	PF08719	phrog_1017
IMGVR_UViG_3300032157_000001\|3300032157\|Ga0315912_10000035263	36.600	4.326E-26	103	0.917%			IMGVR	PF08719	phrog_1017
IMGVR_UViG_3300032220_001761\|3300032220\|Ga0335256_145614158	40.700	1.912E-30	116	0.889%			IMGVR	PF08719	phrog_1017
IMGVR_UViG_GVMAG-M-3300017963-43_000001\|3300017963\|Ga0180437_10000057247	42.800	6.737E-33	123	0.883%			IMGVR	PF08719	phrog_1017
IMGVR_UViG_3300029305_005212\|3300029305\|Ga0307249_1000491735	39.900	5.397E-28	109	0.856%			IMGVR	PF08719	phrog_1017
IMGVR_UViG_3300035182_002586\|3300035182\|Ga0373636_0000001_564792_565310	38.500	1.381E-27	108	0.889%			IMGVR	PF08719	phrog_1017
IMGVR_UViG_3300034073_003542\|3300034073\|Ga0310130_0000026_110886_111386	39.900	2.108E-28	110	0.867%			IMGVR	PF08719	phrog_1017
IMGVR_UViG_3300009545_000018\|3300009545\|Ga0105237_10000004316	40.300	2.350E-29	113	0.878%			IMGVR	PF08719	phrog_1017
IMGVR_UViG_3300037475_000199\|3300037475\|Ga0400313_0000015_12095_12592	39.900	6.018E-29	111	0.878%			IMGVR	PF08719	phrog_1017
IMGVR_UViG_3300025914_000008\|3300025914\|Ga0207671_10000017364	40.300	2.350E-29	113	0.878%			IMGVR	PF08719	phrog_1017
AP018399_00238	41.000	4.899E-30	115	0.872%	Xanthomonas phage XacN1	Xanthomonas	INPHARED	PF08719	phrog_1017
IMGVR_UViG_3300019487_000031\|3300019487\|Ga0187893_1000117060	36.900	2.584E-27	107	0.939%			IMGVR	PF08719	phrog_1017
IMGVR_UViG_3300000156_000113\|3300000156\|NODE_074788963	41.000	7.462E-31	117	0.889%			IMGVR	PF08719	phrog_1017
MGV-GENOME-0371044_50	39.300	1.397E-30	116	0.939%			MGV	PF08719	phrog_1017
uvig_180451_35	39.600	2.911E-31	118	0.944%			GPD	PF08719	phrog_1017
IMGVR_UViG_3300042292_000567\|3300042292\|Ga0453156_0000158_2110_2595	37.800	1.717E-29	113	0.961%			IMGVR	PF08719	phrog_1017
KJ591605_00182	40.000	8.233E-29	111	0.867%	Listeria phage LMTA-57	Listeria	INPHARED	PF08719	phrog_1017
MN939540_00062	39.000	1.889E-27	107	0.867%	Listeria phage vB_Liva_VAfA18	Listeria	INPHARED	PF08719	phrog_1017
DQ003638_00047	40.000	8.233E-29	111	0.867%	Listeria phage A511	Listeria	INPHARED	PF08719	phrog_1017
MN939539_00059	39.900	1.126E-28	111	0.867%	Listeria phage vB_Lino_VEfB7	Listeria	INPHARED	PF08719	phrog_1017
MT668624_00052	39.500	3.945E-28	109	0.867%	Listeria phage LP-Mix_6.2	Listeria	INPHARED	PF08719	phrog_1017
DQ004855_00164	38.600	4.834E-27	106	0.867%	Listeria phage P100	Listeria	INPHARED	PF08719	phrog_1017
MT668623_00048	39.500	3.945E-28	109	0.867%	Listeria phage LP-Mix_6.1	Listeria	INPHARED	PF08719	phrog_1017
MK792752_00163	38.900	2.584E-27	107	0.867%	Listeria phage vB-LmoM-SH3-3	Listeria	INPHARED	PF08719	phrog_1017
MT438761_00072	40.000	8.233E-29	111	0.867%	Listeria virus P61	Listeria	INPHARED	PF08719	phrog_1017
KM373208_00030	39.000	1.889E-27	107	0.867%	Listeria phage WIL-1	Listeria	INPHARED	PF08719	phrog_1017
KJ668715_00126	40.000	8.233E-29	111	0.867%	Listeria phage LMTA-34	Listeria	INPHARED	PF08719	phrog_1017
IMGVR_UViG_3300033121_001850\|3300033121\|Ga0364571_1025111	39.600	2.313E-26	104	0.828%			IMGVR	PF08719	phrog_1017
IMGVR_UViG_3300045988_177541\|3300045988\|Ga0495776_060668_198672_199142	38.000	8.233E-29	111	0.939%			IMGVR	PF08719	phrog_1017
MGV-GENOME-0379723_212	38.000	8.233E-29	111	0.939%			MGV	PF08719	phrog_1017
IMGVR_UViG_2597490056_000001\|2597490056\|2598204354	40.300	3.215E-29	112	0.872%			IMGVR	PF08719	phrog_1017
IMGVR_UViG_3300005965_000002\|3300005965\|Ga0081527_10000747	36.900	2.584E-27	107	0.939%			IMGVR	PF08719	phrog_1017
uvig_101162_329	40.500	3.215E-29	112	0.867%			GPD	PF08719	phrog_1017
IMGVR_UViG_3300023208_000007\|3300023208\|Ga0233424_1000038796	38.400	1.889E-27	107	0.889%			IMGVR	PF08719	phrog_1017
IMGVR_UViG_3300024054_000019\|3300024054\|Ga0233425_1000127696	38.400	1.889E-27	107	0.889%			IMGVR	PF08719	phrog_1017
IMGVR_UViG_GVMAG-M-3300017971-33_000001\|3300017971\|Ga0180438_100026659	43.300	3.237E-32	121	0.856%			IMGVR	PF08719	phrog_1017
IMGVR_UViG_3300032242_002192\|3300032242\|Ga0335274_144810366	40.000	1.541E-28	110	0.867%			IMGVR	PF08719	phrog_1017
MGV-GENOME-0374301_181	37.700	1.381E-27	108	0.917%		Agathobacter	MGV	PF08719	phrog_1017
MGV-GENOME-0379222_226	37.700	1.381E-27	108	0.917%		Agathobacter	MGV	PF08719	phrog_1017
MGV-GENOME-0379306_43	37.800	1.010E-27	108	0.917%		Agathobacter	MGV	PF08719	phrog_1017
IMGVR_UViG_3300045988_163932\|3300045988\|Ga0495776_005799_22621_23106	37.800	1.010E-27	108	0.917%			IMGVR	PF08719	phrog_1017
uvig_4113_19	37.700	1.381E-27	108	0.917%			GPD	PF08719	phrog_1017
uvig_558919_226	37.700	1.381E-27	108	0.917%			GPD	PF08719	phrog_1017
uvig_569865_97	38.800	4.398E-29	112	0.917%			GPD	PF08719	phrog_1017
MN871445_00268	41.600	2.363E-35	130	0.972%	Serratia phage KpHz_2	Serratia	INPHARED	PF08719	phrog_1017
MN871444_00195	39.900	6.737E-33	123	0.972%	Serratia phage KpGz_1	Serratia	INPHARED	PF08719	phrog_1017
LR881104_00315	41.500	3.235E-35	130	0.972%	Klebsiella phage vB_KvM-Eowyn	Klebsiella	INPHARED	PF08719	phrog_1017
IMGVR_UViG_3300010357_000510\|3300010357\|Ga0116249_1000297112	42.200	2.127E-31	119	0.867%			IMGVR	PF08719	phrog_1017
IMGVR_UViG_GVMAG-M-3300023174-165_000001\|3300023174\|Ga0214921_1000440910	41.600	1.381E-27	108	0.800%			IMGVR	PF08719	phrog_1017
MGV-GENOME-0375924_195	94.600	4.950E-115	360	1.000%			MGV	PF08719	phrog_1017
IMGVR_UViG_3300014004_000001\|3300014004\|Ga0122311_10001055	93.300	1.093E-109	344	0.972%			IMGVR	PF08719	phrog_1017
YP_009986712.1	100.000	7.400E-126	391	1.000%	Escherichia phage Ukendt	Escherichia	NCBI	PF08719 PF08719	phrog_1017 phrog_1017
OP595145_00255	99.400	3.707E-122	380	1.000%	Escherichia phage vB_EcoM_DE16	Escherichia	INPHARED	PF08719	phrog_1017
OP562383_00255	94.300	1.276E-114	359	1.000%	Acinetobacter phage vB_AbaM_ ABPW7	Acinetobacter	INPHARED	PF08719	phrog_1017
LC739539_00219	90.900	2.913E-106	334	0.972%	Escherichia phage phiWec190	Escherichia	INPHARED	PF08719	phrog_1017
OM386667_00261	100.000	4.914E-125	389	1.000%	Escherichia phage vB_EcoM_REC	Escherichia	INPHARED	PF08719	phrog_1017
OP172792_00031	91.100	6.607E-108	339	0.983%	Escherichia phage ECO340P2	Escherichia	INPHARED	PF08719	phrog_1017
MK373788_00252	100.000	2.380E-124	387	1.000%	Escherichia phage vB_EcoM_Schickermooser	Escherichia	INPHARED	PF08719	phrog_1017
OP172791_00026	99.200	9.553E-122	379	1.000%	Escherichia phage ECO340P1	Escherichia	INPHARED	PF08719	phrog_1017
LC739535_00293	92.200	4.819E-108	340	0.972%	Escherichia phage phiWec186	Escherichia	INPHARED	PF08719	phrog_1017
KX664695_00255	91.900	4.660E-111	348	1.000%	Escherichia phage ESCO5	Escherichia	INPHARED	PF08719	phrog_1017
MN850618_00050	92.800	2.724E-112	352	1.000%	Escherichia phage tuntematon	Escherichia	INPHARED	PF08719	phrog_1017
OQ031492_00245	92.200	1.809E-111	349	1.000%	Escherichia phage MRostami-2023b	Escherichia	INPHARED	PF08719	phrog_1017
MW175890_00116	91.800	7.258E-109	342	0.983%	Dompiswa phage TSP7_1	Dompiswa	INPHARED	PF08719	phrog_1017
OM362897_00179	91.700	1.201E-110	347	1.000%	Escherichia phage SKA64	Escherichia	INPHARED	PF08719	phrog_1017
MT496970_00037	91.800	7.258E-109	342	0.983%	Escherichia phage Mt1B1_P17	Escherichia	INPHARED	PF08719	phrog_1017
uvig_174847_195	94.600	4.950E-115	360	1.000%			GPD	PF08719	phrog_1017
MG065650_00014	90.800	2.055E-109	344	1.000%	Campylobacter phage B15	Campylobacter	INPHARED	PF08719	phrog_1017
OL739525_00256	94.200	2.724E-112	352	0.983%	Escherichia phage dw-ec	Escherichia	INPHARED	PF08719	phrog_1017
MZ726793_00268	91.200	5.816E-110	345	1.000%	Escherichia phage vB_EcoM_ASO2A	Escherichia	INPHARED	PF08719	phrog_1017
MT944117_00072	91.000	1.093E-109	344	1.000%	Escherichia phage PNJ1809-36	Escherichia	INPHARED	PF08719	phrog_1017
IMGVR_UViG_GVMAG-S-1016713-46_000001\|3300025874\|Ga0209533_10031168	40.300	1.255E-29	113	0.883%			IMGVR	PF08719	phrog_1017
LT960552_00163	39.200	2.108E-28	110	0.889%	Yersinia phage fHe-Yen9-03	Yersinia	INPHARED	PF08719	phrog_1017
MW879344_00168	37.300	4.899E-30	115	0.994%	Erwinia phage pEa_SNUABM_49	Erwinia	INPHARED	PF08719	phrog_1017
LR596615_00160	39.500	8.233E-29	111	0.889%	Yersinia phage fHe-Yen9-04	Yersinia	INPHARED	PF08719	phrog_1017
KU574722_00168	40.400	4.899E-30	115	0.889%	Pectinobacterium phage vB_PcaM_CBB	Pectobacterium	INPHARED	PF08719	phrog_1017