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Seed proteins  | Seed genomic context  | Seed protein 3D structures  |  Structural homologs  |  Family infomation  | Homology to other families  | Family members, sources, and their hosts  

Seed protein information help

APIS family ID APIS165
Inhibited defense system restriction-modification (RM)
CLAN ID CLAN062
Seed protein property
Accession ID Gene name Protein length Molecular weight Isoelectric point Charge
YP_006493.1 gene_page: Ddra 121 13013.56 3.8317 -14.0
Phage property
Phage Assembly id
Escherichia phage P1 GCF_000844165.1
PMID/References PMID:28509398
PDB structures ;
Pfam domains
Phrog phrog_1855,phrog_1855
Host taxa d__Bacteria;p__Proteobacteria;c__Gammaproteobacteria;o__Enterobacterales;f__Enterobacteriaceae;g__Escherichia;
Gene Location Start: 27542;  End: 27907;  Strand: -
Description It's included in the P1 restriction system. The proteins Hdf, DarA and DdrA are required for the protection of phage DNA from restriction by the EcoA Type I R-M system.

Seed genomic context      Download table help

Genome accession Start End Strand Protein ID Length Molecular weight Charge Isoelectric point Function Phrog PFAM
NC_005856.1 23063 23338 - YP_006488.1 91 9902.38 12.0 10.8604 transposase phrog_1191 ; phrog_720 PF12759.12 ;PF03811.18
NC_005856.1 23527 24132 + YP_006489.1 201 23633.87 4.0 7.7642 IsaB phrog_30162
NC_005856.1 24244 24552 - YP_006490.1 102 11034.04 -20.0 3.4283 Hxr phrog_2292
NC_005856.1 24542 27529 - YP_006491.1 995 108753.15 -13.5 5.4395 DdrB phrog_2299 ; phrog_2299 ; phrog_5143 ; phrog_5143 ; phrog_14693 ; phrog_14693 ; phrog_1849 ; phrog_1849 PF18763.6 ;PF18763.6
NC_005856.1 26577 26975 + YP_006492.1 132 13541.06 14.0 11.4674 IddB
NC_005856.1 27542 27907 - YP_006493.1 121 13013.56 -14.0 3.8317 DdrA-like anti-restriction protein phrog_1855 ; phrog_1855
NC_005856.1 27904 29823 - YP_006494.1 639 69479.93 -28.0 4.4870 released from the phage upon host infection phrog_1639 ; phrog_26978 ; phrog_1926 PF18788.6 ;PF18789.6
NC_005856.1 29825 30436 - YP_006495.1 203 22151.46 21.0 10.9850 Hdf-like antirestriction phrog_1620 ; phrog_1620 PF18788.6 ;PF18788.6
NC_005856.1 30414 30857 - YP_006496.1 147 17097.72 2.5 7.8661 lysis determining protein phrog_1898 ; phrog_18375 PF16084.10
NC_005856.1 30854 31183 - YP_006497.1 109 11466.42 -1.0 5.6051 holin phrog_1527 PF16083.10
NC_005856.1 31251 31532 - YP_006498.1 93 10450.29 -0.5 5.7511 LydC phrog_11376 ; phrog_1527 ; phrog_18875 ; phrog_32746 PF16083.10

Seed genomic context- JBrowse     

Predicted 3D structure by alphafold2 with pTM = 0.41 Download help

pTM is for the estimate of the TM-score, which is obtained from a pairwise error prediction. The higher pTM score indicates better model quality.

pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .

Residues were colored according to plddt ( blue-> high quality; red-> low quality ).

Full Sequence
90 < plddt <=100 ;
70 < plddt <= 90 ;
50 < plddt <= 70 ;
0 <= plddt <= 50 ;      Download help

Structural homologs

No homologs found in AlphaFold database

No homologs found in esmfold database

Family information      Download help

Fam ID Seed protein Member count Model Alignment
APIS165 YP_006493.1 100 HMM model Member alignment

Host Taxa distribution

Length distribution

Homology to other families       help

Clan ID: CLAN062

APIS165 has no similar APIS family.

Family members, sources, and their hosts        help

Results of representative protein blast against members.

Member pident evalue bitscore qcovs phage host SourceDB Pfam Phrog
IMGVR_UViG_2906128962_000004|2906128962|2906129960 44.200 1.874E-25 98 1.000% Citrobacter freundii IMGVR phrog_1855
IMGVR_UViG_2887663082_000001|2887663082|2887664586 45.000 2.816E-26 101 1.000% Pseudocitrobacter faecalis IMGVR phrog_1855
IMGVR_UViG_3300048929_000411|3300048929|Ga0496126_0018568_2061_2411 51.400 5.557E-30 111 0.934% IMGVR phrog_1855
IMGVR_UViG_3300009011_000349|3300009011|Ga0105251_1000008339 42.600 1.874E-25 98 0.917% Enterobacteriaceae IMGVR phrog_1855
IMGVR_UViG_3300048922_000287|3300048922|Ga0496119_0005925_533_940 43.400 2.816E-26 101 0.917% IMGVR phrog_1855
IMGVR_UViG_3300013827_000023|3300013827|Ga0121238_10003047 43.400 2.816E-26 101 0.917% IMGVR phrog_1855
IMGVR_UViG_3300025735_000294|3300025735|Ga0207713_100018236 42.600 1.874E-25 98 0.917% IMGVR phrog_1855
IMGVR_UViG_2713896898_000005|2713896898|2714781775 89.200 1.662E-69 225 0.992% Escherichia albertii IMGVR phrog_1855
MGV-GENOME-0359519_100 87.500 1.517E-68 222 1.000% Escherichia MGV phrog_1855
MGV-GENOME-0348064_85 89.500 1.820E-70 228 1.000% Escherichia MGV phrog_1855
MGV-GENOME-0360483_105 87.500 1.517E-68 222 1.000% Escherichia MGV phrog_1855
IMGVR_UViG_2529292906_000012|2529292906|2530459872 87.700 1.320E-63 208 0.934% Escherichia coli IMGVR phrog_1855
IMGVR_UViG_2563366895_000001|2563366895|2564543598 88.500 1.662E-69 225 1.000% Escherichia coli IMGVR phrog_1855
AF503408_00021 89.300 2.496E-70 228 1.000% Enterobacteria phage P7 Enterobacteria INPHARED phrog_1855
MGV-GENOME-0360966_101 88.900 6.440E-70 226 1.000% Escherichia MGV phrog_1855
IMGVR_UViG_2529292911_000006|2529292911|2530486566 90.000 8.418E-66 214 0.934% Escherichia coli IMGVR phrog_1855
IMGVR_UViG_2537562194_000013|2537562194|2540134968 89.300 2.496E-70 228 1.000% Escherichia coli IMGVR phrog_1855
IMGVR_UViG_2548876949_000015|2548876949|2550467194 88.900 6.440E-70 226 1.000% Escherichia coli IMGVR phrog_1855
uvig_116148_7 89.500 1.820E-70 228 1.000% Escherichia coli GPD phrog_1855
IMGVR_UViG_2531839476_000011|2531839476|2533675630 89.600 2.172E-65 213 0.934% Escherichia coli IMGVR phrog_1855
IMGVR_UViG_2684622670_000004|2684622670|2685304377 87.800 8.064E-69 223 1.000% Escherichia albertii IMGVR phrog_1855
IMGVR_UViG_2574180358_000003|2574180358|2576529901 89.700 9.675E-71 229 1.000% Escherichia coli IMGVR phrog_1855
IMGVR_UViG_2939121850_000001|2939121850|2939126757 88.800 8.833E-70 226 1.000% Escherichia coli IMGVR phrog_1855
uvig_417949_7 89.500 1.820E-70 228 1.000% GPD phrog_1855
IMGVR_UViG_2698536628_000013|2698536628|2699851664 87.400 2.081E-68 222 1.000% Escherichia coli IMGVR phrog_1855
uvig_297943_7 86.700 1.010E-67 220 1.000% GPD phrog_1855
MGV-GENOME-0359735_7 89.500 1.820E-70 228 1.000% Escherichia MGV phrog_1855
MGV-GENOME-4433070_98 88.100 4.287E-69 224 1.000% Escherichia MGV phrog_1855
IMGVR_UViG_2645727574_000001|2645727574|2646059968 88.300 1.106E-68 223 0.992% Salmonella enterica IMGVR phrog_1855
IMGVR_UViG_2802429224_000004|2802429224|2804580057 90.100 1.820E-70 228 0.992% Escherichia marmotae IMGVR phrog_1855
MGV-GENOME-0361826_74 88.500 1.662E-69 225 1.000% Escherichia MGV phrog_1855
IMGVR_UViG_2913167280_000003|2913167280|2913171169 90.600 1.454E-71 231 1.000% Escherichia sp005843885 IMGVR phrog_1855
uvig_215654_8 87.100 3.914E-68 221 1.000% GPD phrog_1855
IMGVR_UViG_2534681604_000014|2534681604|2534705183 88.300 1.106E-68 223 0.992% Escherichia fergusonii IMGVR phrog_1855
IMGVR_UViG_2711768056_000005|2711768056|2712048056 90.700 1.060E-71 231 1.000% Escherichia coli IMGVR phrog_1855
uvig_325413_10 89.100 4.696E-70 227 1.000% GPD phrog_1855
MGV-GENOME-0357176_59 89.300 1.211E-69 226 0.992% Escherichia MGV phrog_1855
IMGVR_UViG_2529293038_000017|2529293038|2530952883 88.100 5.117E-64 209 0.934% Escherichia coli IMGVR phrog_1855
uvig_48503_7 89.900 7.054E-71 229 1.000% GPD phrog_1855
MGV-GENOME-0358589_7 89.500 1.820E-70 228 1.000% Escherichia MGV phrog_1855
IMGVR_UViG_2675903433_000020|2675903433|2677952458 89.700 9.675E-71 229 1.000% Escherichia coli IMGVR phrog_1855
IMGVR_UViG_649989947_000012|649989947|650100772 90.600 2.379E-66 216 0.934% Escherichia coli IMGVR phrog_1855
uvig_422525_7 89.300 1.211E-69 226 0.992% GPD phrog_1855
IMGVR_UViG_2541047595_000013|2541047595|2543553092 90.200 6.137E-66 215 0.934% Escherichia coli IMGVR phrog_1855
KU760857_00041 86.800 7.362E-68 220 1.000% Salmonella phage SJ46 Salmonella INPHARED phrog_1855
IMGVR_UViG_3300029516_000004|3300029516|Ga0244799_10015210 88.300 1.106E-68 223 0.992% Escherichia IMGVR phrog_1855
IMGVR_UViG_2737471831_000002|2737471831|2737940924 88.500 1.662E-69 225 1.000% Escherichia coli IMGVR phrog_1855
FO818745_00031 88.100 4.287E-69 224 1.000% Escherichia phage RCS47 Escherichia INPHARED phrog_1855
uvig_336370_7 89.500 1.820E-70 228 1.000% GPD phrog_1855
IMGVR_UViG_2534681832_000025|2534681832|2535621557 88.700 1.446E-64 211 0.934% Escherichia coli IMGVR phrog_1855
IMGVR_UViG_2737471833_000002|2737471833|2737949098 89.300 1.211E-69 226 0.992% Escherichia coli IMGVR phrog_1855
MGV-GENOME-0358739_97 86.700 1.010E-67 220 1.000% Escherichia MGV phrog_1855
IMGVR_UViG_2534681951_000013|2534681951|2536098778 90.800 7.728E-72 232 1.000% Salmonella enterica IMGVR phrog_1855
IMGVR_UViG_2713896905_000004|2713896905|2714815717 88.600 5.880E-69 224 0.992% Escherichia albertii IMGVR phrog_1855
IMGVR_UViG_3300015157_000095|3300015157|Ga0181864_12484145 88.800 8.833E-70 226 1.000% Escherichia IMGVR phrog_1855
IMGVR_UViG_2724679238_000011|2724679238|2725986977 85.100 1.584E-65 214 0.992% Escherichia albertii IMGVR phrog_1855
ON470617_00007 87.500 1.517E-68 222 1.000% Escherichia phage vB_EcoM-813R1 Escherichia INPHARED phrog_1855
ON018986_00017 87.500 1.517E-68 222 1.000% Escherichia phage JL22 Escherichia INPHARED phrog_1855
MH445380_00138 89.500 1.820E-70 228 1.000% Escherichia phage P1 Escherichia INPHARED phrog_1855
IMGVR_UViG_2526164690_000035|2526164690|2526988793 89.100 1.577E-58 194 0.851% Escherichia coli IMGVR phrog_1855
IMGVR_UViG_2703718837_000002|2703718837|2704704314 87.500 1.517E-68 222 1.000% Escherichia coli IMGVR phrog_1855
IMGVR_UViG_2713896909_000009|2713896909|2714833035 88.700 4.287E-69 224 0.992% Escherichia albertii IMGVR phrog_1855
MGV-GENOME-0359323_7 89.900 7.054E-71 229 1.000% Escherichia MGV phrog_1855
IMGVR_UViG_3300015177_000009|3300015177|Ga0183240_10069911 87.200 1.385E-67 220 0.992% Escherichia IMGVR phrog_1855
YP_006493.1 100.000 1.592E-72 234 1.000% Escherichia phage P1 Escherichia NCBI phrog_1855 phrog_1855
MGV-GENOME-0360185_99 89.100 4.696E-70 227 1.000% Escherichia MGV phrog_1855
IMGVR_UViG_2537561935_000012|2537561935|2539212862 86.400 1.900E-67 219 1.000% Escherichia coli IMGVR phrog_1855
uvig_71109_84 87.800 3.914E-68 221 0.992% GPD phrog_1855
MGV-GENOME-0360360_8 87.100 3.914E-68 221 1.000% Escherichia MGV phrog_1855
IMGVR_UViG_3300045988_161728|3300045988|Ga0495776_027236_86933_87298 88.900 6.440E-70 226 1.000% Escherichia IMGVR phrog_1855
uvig_112992_74 88.500 1.662E-69 225 1.000% Escherichia coli GPD phrog_1855
MGV-GENOME-0359986_100 89.300 2.496E-70 228 1.000% Escherichia MGV phrog_1855
IMGVR_UViG_2684622652_000002|2684622652|2685242126 69.500 1.438E-50 171 1.000% Salmonella enterica IMGVR phrog_1855
MZ188976_00114 70.100 2.961E-51 173 1.000% Cronobacter phage JK004 Cronobacter INPHARED phrog_1855
uvig_130648_20 70.400 1.574E-51 173 1.000% GPD phrog_1855
IMGVR_UViG_2531839377_000006|2531839377|2533300585 69.600 1.048E-50 171 1.000% Salmonella enterica IMGVR phrog_1855
IMGVR_UViG_2773857937_000002|2773857937|2774920326 69.200 2.705E-50 170 1.000% Citrobacter braakii IMGVR phrog_1855
IMGVR_UViG_2871745582_000001|2871745582|2871747306 54.300 8.738E-35 125 0.983% Pantoea sp002920175 IMGVR phrog_1855
IMGVR_UViG_3300013000_000010|3300013000|Ga0157360_100002965 43.400 2.816E-26 101 0.959% Enterobacteriaceae IMGVR phrog_1855
IMGVR_UViG_3300031414_000105|3300031414|Ga0308168_10015822 44.100 5.803E-27 103 0.959% IMGVR phrog_1855
IMGVR_UViG_3300027718_000111|3300027718|Ga0209795_1000266010 43.300 3.862E-26 100 0.959% IMGVR phrog_1855
IMGVR_UViG_3300048921_000142|3300048921|Ga0496118_0013977_4547_4942 42.100 6.630E-25 97 0.959% IMGVR phrog_1855
IMGVR_UViG_3300030434_000006|3300030434|Ga0134873_1002112 43.400 2.816E-26 101 0.959% Gammaproteobacteria IMGVR phrog_1855
IMGVR_UViG_3300031417_000419|3300031417|Ga0308170_10000188113 43.700 1.497E-26 102 0.959% IMGVR phrog_1855
IMGVR_UViG_3300013104_000023|3300013104|Ga0157370_1000013383 42.600 1.874E-25 98 0.959% IMGVR phrog_1855
IMGVR_UViG_3300031418_000067|3300031418|Ga0308166_100096427 43.300 3.862E-26 100 0.959% IMGVR phrog_1855
IMGVR_UViG_3300031087_000025|3300031087|Ga0308161_100051313 42.400 3.525E-25 98 0.959% IMGVR phrog_1855
IMGVR_UViG_3300028585_000021|3300028585|Ga0265797_1000032795 42.900 9.963E-26 99 0.959% IMGVR phrog_1855
IMGVR_UViG_3300031110_000318|3300031110|Ga0308165_10062023 43.700 1.497E-26 102 0.959% IMGVR phrog_1855
IMGVR_UViG_3300028585_000074|3300028585|Ga0265797_100046472 43.000 7.265E-26 100 0.959% IMGVR phrog_1855
IMGVR_UViG_3300042922_000661|3300042922|Ga0456363_0000484_91545_91940 43.800 1.092E-26 102 0.959% IMGVR phrog_1855
IMGVR_UViG_2871731064_000001|2871731064|2871735526 43.200 5.297E-26 100 0.959% Pantoea agglomerans IMGVR phrog_1855
IMGVR_UViG_3300009036_000379|3300009036|Ga0105244_1000362510 42.900 9.963E-26 99 0.959% IMGVR phrog_1855
IMGVR_UViG_3300048909_000129|3300048909|Ga0496106_0009004_5235_5630 43.800 1.092E-26 102 0.959% IMGVR phrog_1855 phrog_15846
IMGVR_UViG_3300025711_000239|3300025711|Ga0207696_1000035197 43.200 5.297E-26 100 0.959% IMGVR phrog_1855
IMGVR_UViG_3300009092_000013|3300009092|Ga0105250_10000075101 43.200 5.297E-26 100 0.959% Gammaproteobacteria IMGVR phrog_1855
IMGVR_UViG_3300048919_000209|3300048919|Ga0496116_0006064_8481_8876 44.300 3.085E-27 104 0.959% IMGVR phrog_1855
IMGVR_UViG_3300011471_000001|3300011471|Ga0121060_10004455 42.900 9.963E-26 99 0.959% IMGVR phrog_1855
IMGVR_UViG_3300031413_000007|3300031413|Ga0308164_1000059117 42.900 9.963E-26 99 0.959% IMGVR phrog_1855 phrog_15846
IMGVR_UViG_3300031413_000047|3300031413|Ga0308164_100018396 43.200 5.297E-26 100 0.959% IMGVR phrog_1855