APIS family ID | APIS179 | |||||||||||||
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Inhibited defense system | restriction-modification (RM) | |||||||||||||
CLAN ID | CLAN063 | |||||||||||||
Seed protein property |
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Phage property |
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PMID/References | PMID:28509398 | |||||||||||||
PDB structures | ; | |||||||||||||
Pfam domains | PF18763.6,PF18763.6 | |||||||||||||
Phrog | phrog_1849,phrog_1849,phrog_5143,phrog_5143,phrog_2299,phrog_2299,phrog_14693,phrog_14693 | |||||||||||||
Host taxa | d__Bacteria;p__Proteobacteria;c__Gammaproteobacteria;o__Enterobacterales;f__Enterobacteriaceae;g__Escherichia; | |||||||||||||
Gene Location | Start: 24542; End: 27529; Strand: - | |||||||||||||
Description | It's included in the P1 restriction system. The presence of DdrB results in reduced antirestriction activity, presumably by negatively affecting DarB but the mechanism is not known. |
Genome accession | Start | End | Strand | Protein ID | Length | Molecular weight | Charge | Isoelectric point | Function | Phrog | PFAM |
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NC_005856.1 | 21569 | 22531 | + | YP_006486.1 | 320 | 36001.51 | -0.5 | 6.3864 | IsaA | phrog_2326 | |
NC_005856.1 | 22641 | 23144 | - | YP_006487.1 | 167 | 19742.88 | 19.5 | 10.8526 | transposase | phrog_2126 ; phrog_720 ; phrog_22515 ; phrog_11245 ; phrog_9690 | PF03400.18 |
NC_005856.1 | 23063 | 23338 | - | YP_006488.1 | 91 | 9902.38 | 12.0 | 10.8604 | transposase | phrog_1191 ; phrog_720 | PF12759.12 ;PF03811.18 |
NC_005856.1 | 23527 | 24132 | + | YP_006489.1 | 201 | 23633.87 | 4.0 | 7.7642 | IsaB | phrog_30162 | |
NC_005856.1 | 24244 | 24552 | - | YP_006490.1 | 102 | 11034.04 | -20.0 | 3.4283 | Hxr | phrog_2292 | |
NC_005856.1 | 24542 | 27529 | - | YP_006491.1 | 995 | 108753.15 | -13.5 | 5.4395 | DdrB | phrog_2299 ; phrog_2299 ; phrog_5143 ; phrog_5143 ; phrog_14693 ; phrog_14693 ; phrog_1849 ; phrog_1849 | PF18763.6 ;PF18763.6 |
NC_005856.1 | 26577 | 26975 | + | YP_006492.1 | 132 | 13541.06 | 14.0 | 11.4674 | IddB | ||
NC_005856.1 | 27542 | 27907 | - | YP_006493.1 | 121 | 13013.56 | -14.0 | 3.8317 | DdrA-like anti-restriction protein | phrog_1855 ; phrog_1855 | |
NC_005856.1 | 27904 | 29823 | - | YP_006494.1 | 639 | 69479.93 | -28.0 | 4.4870 | released from the phage upon host infection | phrog_1639 ; phrog_26978 ; phrog_1926 | PF18788.6 ;PF18789.6 |
NC_005856.1 | 29825 | 30436 | - | YP_006495.1 | 203 | 22151.46 | 21.0 | 10.9850 | Hdf-like antirestriction | phrog_1620 ; phrog_1620 | PF18788.6 ;PF18788.6 |
NC_005856.1 | 30414 | 30857 | - | YP_006496.1 | 147 | 17097.72 | 2.5 | 7.8661 | lysis determining protein | phrog_1898 ; phrog_18375 | PF16084.10 |
pTM is for the estimate of the TM-score, which is obtained from a pairwise error prediction. The higher pTM score indicates better model quality.
pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .
Fam ID | Seed protein | Member count | Model | Alignment | APIS179 | YP_006491.1 | 285 | HMM model | Member alignment |
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