PUL ID

PUL0088

PubMed

8764489, FEMS Microbiol Lett. 1996 Jul 1;140(2-3):261-4. doi: 10.1016/0378-1097(96)00191-7.

Characterization method

Southern Blot

Genomic accession number

M77351.1

Nucelotide position range

290-10896

Substrate

raffinose,melibiose,isomaltotriose

Loci

msmR-aga-msmEFG-gtfA-memK-dexB

Species

Streptococcus mutans/1309

Degradation or Biosynthesis

degradation

Gene Name

Locus Tag

Protein ID

Gene Position

GenBank Contig Range

EC Number

msmR - AAA26932.1 290 - 1141 (-) M77351.1:580-1431 -
aga - AAA26933.1 1235 - 3398 (+) M77351.1:1525-3688 3.2.1.22
msmE - AAA26934.1 3410 - 4673 (+) M77351.1:3700-4963 -
msmF - AAA26935.1 4685 - 5558 (+) M77351.1:4975-5848 -
msmG - AAA26936.1 5572 - 6406 (+) M77351.1:5862-6696 -
gftA - AAA26937.1 6601 - 8047 (+) M77351.1:6891-8337 2.4.1.7
msmK - AAA26938.1 8061 - 9195 (+) M77351.1:8351-9485 -
dexB - AAA26939.1 9285 - 10896 (+) M77351.1:9575-11186 3.2.1.70

Cluster number

1

Gene name

Gene position

Gene type

Found by CGCFinder?

- 291 - 1127 (-) TF: DBD-Pfam|HTH_AraC,DBD-Pfam|HTH_AraC,DBD-Pfam|HTH_AraC,DBD-SUPERFAMILY|0036286,DBD-SUPERFAMILY|0035607,DBD-SUPERFAMILY|0035607 No
- 1236 - 3398 (+) CAZyme: GH36 Yes
- 3411 - 4673 (+) TC: gnl|TC-DB|Q00749|3.A.1.1.28 Yes
- 4686 - 5558 (+) TC: gnl|TC-DB|Q00750|3.A.1.1.28 Yes
- 5573 - 6406 (+) TC: gnl|TC-DB|Q00751|3.A.1.1.28 Yes
- 6602 - 8047 (+) CAZyme: GH13_18|GH13 Yes
- 8062 - 9195 (+) TC: gnl|TC-DB|Q00752|3.A.1.1.28 Yes
- 9286 - 10896 (+) TC: gnl|TC-DB|Q05839|8.A.9.1.1 Yes

PUL ID

PUL0088

PubMed

8764489, FEMS Microbiol Lett. 1996 Jul 1;140(2-3):261-4. doi: 10.1016/0378-1097(96)00191-7.

Title

The multiple-sugar metabolism (msm) gene cluster of Streptococcus mutans is transcribed as a single operon.

Author

McLaughlin RE, Ferretti JJ

Abstract

The multiple-sugar metabolism (msm) locus of Streptococcus mutans constitutes a non-PTS sugar uptake system responsible for the transport and utilization of raffinose, melibiose and isomaltotrioses. While previous studies have used polar mutations to suggest that these genes are co-transcribed, there has not been evidence to support this. In this report we present direct evidence that the msm genes can be transcribed as a single operon.