| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra034388 |
| Family | GH29 |
| Protein Properties | Length: 497 Molecular Weight: 55823.1 Isoelectric Point: 4.9714 |
| Chromosome | Chromosome/Scaffold: 04 Start: 12281752 End: 12283341 |
| Description | alpha-L-fucosidase 1 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH29 | 35 | 332 | 0 |
| QQLQWQLGSMSMFLHFGPNTFTDSEWGTGKADPSVFNPAHLNATQWVQIAKDSGFSRVILTAKHHDGFCLWPSDYTDYSVKSSPWRNGTGDVVAELASAA AEAGIGLGLYLSPWDRHDGAYGKTLEYNEFYLSQMTELLTKYGEIKEVWLDGAKGEGEKDMEYYFTTWFSLIHQLQPGAVIFSDAGPDVRWIGDEAGVAG STCWSLFNRTDAKIGDTDPLYSQQGDGFGQDWVPAECDVSIRPGWFWHVLESPKPVAKLLDIYYNSVGRNCLFLLNVPPNSSGLISEQDIKVLKEFRE | |||
| Full Sequence |
|---|
| Protein Sequence Length: 497 Download |
| MSLLTLLFFS SLLSLSKSTP LKPHPLPILP LPSSQQLQWQ LGSMSMFLHF GPNTFTDSEW 60 GTGKADPSVF NPAHLNATQW VQIAKDSGFS RVILTAKHHD GFCLWPSDYT DYSVKSSPWR 120 NGTGDVVAEL ASAAAEAGIG LGLYLSPWDR HDGAYGKTLE YNEFYLSQMT ELLTKYGEIK 180 EVWLDGAKGE GEKDMEYYFT TWFSLIHQLQ PGAVIFSDAG PDVRWIGDEA GVAGSTCWSL 240 FNRTDAKIGD TDPLYSQQGD GFGQDWVPAE CDVSIRPGWF WHVLESPKPV AKLLDIYYNS 300 VGRNCLFLLN VPPNSSGLIS EQDIKVLKEF RELKNSIFAN NLALKGFINS TSVRGSQFSA 360 ENVLEEGLDK YWAPEEKQKE WELYLEFRDP VSFNVLEVQE PIQMGQRVAS FHLEMRNVES 420 GKWERVVRGT TVGFKRLLRF PRCESQSLKL VVEKARADPL ISYIGIYMDK FSDSGRNSSK 480 ITITRALQEE LVLNDS* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| smart00812 | Alpha_L_fucos | 3.0e-26 | 70 | 401 | 358 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| pfam01120 | Alpha_L_fucos | 3.0e-27 | 46 | 330 | 317 | + Alpha-L-fucosidase. | ||
| COG3669 | COG3669 | 3.0e-60 | 47 | 467 | 431 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_180377.2 | 0 | 22 | 495 | 28 | 505 | ATFUC1 (alpha-L-fucosidase 1); alpha-L-fucosidase [Arabidopsis thaliana] |
| Swiss-Prot | Q8GW72 | 0 | 22 | 495 | 28 | 505 | FUCO1_ARATH RecName: Full=Alpha-L-fucosidase 1; AltName: Full=Alpha-L-fucoside fucohydrolase; AltName: Full=Alpha-1,3/4-fucosidase; Short=AtFUC1; Flags: Precursor |
| RefSeq | XP_002276131.1 | 0 | 33 | 472 | 51 | 489 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002313533.1 | 0 | 33 | 472 | 15 | 457 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002523703.1 | 0 | 33 | 472 | 64 | 507 | alpha-l-fucosidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3ues_B | 0 | 32 | 462 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3ues_A | 0 | 32 | 462 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3mo4_B | 0 | 32 | 462 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3mo4_A | 0 | 32 | 462 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3uet_B | 0 | 32 | 462 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis D172aE217A MUTANT COMPLEXED WITH LACTO-N- Fucopentaose Ii |
