| Basic Information | |
|---|---|
| Species | Medicago truncatula |
| Cazyme ID | Medtr2g095700.1 |
| Family | GH29 |
| Protein Properties | Length: 538 Molecular Weight: 60394.5 Isoelectric Point: 7.4753 |
| Chromosome | Chromosome/Scaffold: 2 Start: 29584666 End: 29588586 |
| Description | alpha-L-fucosidase 1 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
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| Family | Start | End | Evalue |
| GH29 | 61 | 360 | 0 |
| FQLQWQNSNMALFFHFGTNTFTDSEWGTGQAHPTIFNPTKLNASQWIHVAKDTGFSRVLLTAKHHDGFCLWPSEYTDYSVRSSGWRNGNGDVVADVAAAA GEAGVGFGIYLSPWDRHELCYGDTLRYNQHYLAQMTELLTRYGEIKDVFLDGAKGEGEKNMKYFFESWFSLIHQLQPGAAIFSDSGPDTRWVGNEQGVAG STCWSLFNQSVIEIGGVDNDPQYQKQGDPFGLDWVPALCDVSIRPGWFWHASEHPKSARKLLEIYYKSVGRNCKLLLNVPPNSSGLISAEDIQVLREFSE | |||
| Full Sequence |
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| Protein Sequence Length: 538 Download |
| MKTRLSFSTK IHNPNHKIQT STLLIFPIQT FLIQLLCSSL TPVSSNQTPP PLPILPLPTA 60 FQLQWQNSNM ALFFHFGTNT FTDSEWGTGQ AHPTIFNPTK LNASQWIHVA KDTGFSRVLL 120 TAKHHDGFCL WPSEYTDYSV RSSGWRNGNG DVVADVAAAA GEAGVGFGIY LSPWDRHELC 180 YGDTLRYNQH YLAQMTELLT RYGEIKDVFL DGAKGEGEKN MKYFFESWFS LIHQLQPGAA 240 IFSDSGPDTR WVGNEQGVAG STCWSLFNQS VIEIGGVDND PQYQKQGDPF GLDWVPALCD 300 VSIRPGWFWH ASEHPKSARK LLEIYYKSVG RNCKLLLNVP PNSSGLISAE DIQVLREFSE 360 LRHSIFSHNF AASASLNASS TRGGIQDTRF SPNKVLEEGI HTYWAPEENQ SKWILYINLK 420 KLVSFNVLQV QEPIHMGQRV IKFHLEALNR DGLWKSVVNG TTIGYQRLLL FPKLKSQYLK 480 LVVDKSRAEP LISYLGIYLD PVTVLSEDMP DKKSGTYFNG TQVLRSAMKN DSQSATM* 540 |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01120 | Alpha_L_fucos | 7.0e-22 | 64 | 358 | 313 | + Alpha-L-fucosidase. | ||
| smart00812 | Alpha_L_fucos | 3.0e-22 | 96 | 358 | 280 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| COG3669 | COG3669 | 5.0e-52 | 60 | 498 | 457 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_180377.2 | 0 | 49 | 500 | 29 | 479 | ATFUC1 (alpha-L-fucosidase 1); alpha-L-fucosidase [Arabidopsis thaliana] |
| Swiss-Prot | Q8GW72 | 0 | 49 | 500 | 29 | 479 | FUCO1_ARATH RecName: Full=Alpha-L-fucosidase 1; AltName: Full=Alpha-L-fucoside fucohydrolase; AltName: Full=Alpha-1,3/4-fucosidase; Short=AtFUC1; Flags: Precursor |
| RefSeq | XP_002276131.1 | 0 | 59 | 537 | 51 | 545 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002313533.1 | 0 | 59 | 500 | 15 | 454 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002523703.1 | 0 | 59 | 525 | 64 | 529 | alpha-l-fucosidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3ues_B | 0 | 58 | 493 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3ues_A | 0 | 58 | 493 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3mo4_B | 0 | 58 | 493 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3mo4_A | 0 | 58 | 493 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3eyp_B | 0 | 53 | 498 | 5 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| DY270181 | 289 | 62 | 350 | 0 |
| DV708359 | 293 | 200 | 492 | 0 |
| DY291901 | 284 | 62 | 345 | 0 |
| DY300194 | 281 | 87 | 367 | 0 |
| DY300194 | 32 | 62 | 93 | 0.000003 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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