| Basic Information | |
|---|---|
| Species | Physcomitrella patens |
| Cazyme ID | Pp1s55_131V6.2 |
| Family | GH29 |
| Protein Properties | Length: 417 Molecular Weight: 46797.7 Isoelectric Point: 4.8651 |
| Chromosome | Chromosome/Scaffold: 55 Start: 851066 End: 854044 |
| Description | alpha-L-fucosidase 1 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH29 | 5 | 262 | 0 |
| MDARQWVREAKNAGFKVVILTAKHADGFCLWPSAYTNYSVKSSPWKNGTGDVVREVSDAAREEGLEFGLYMSPWDRHEPTYGDTLLYNDYYLGQLRELLT MYGPISQFFVDGNKDPSSKDMYYLFDAWFALIHQMQPNANIFSDDGPDVRWVGNEAGEAGTTSWSMMNRSMVTIGGPFEEYLNEGDPNGSDWVPPECDVS IRPGWFWKESQQPKTVNKLLDIYYKSVGRNCVMLLNAPPNQTGLLHGTDVANLRDFRS | |||
| Full Sequence |
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| Protein Sequence Length: 417 Download |
| MMMMMDARQW VREAKNAGFK VVILTAKHAD GFCLWPSAYT NYSVKSSPWK NGTGDVVREV 60 SDAAREEGLE FGLYMSPWDR HEPTYGDTLL YNDYYLGQLR ELLTMYGPIS QFFVDGNKDP 120 SSKDMYYLFD AWFALIHQMQ PNANIFSDDG PDVRWVGNEA GEAGTTSWSM MNRSMVTIGG 180 PFEEYLNEGD PNGSDWVPPE CDVSIRPGWF WKESQQPKTV NKLLDIYYKS VGRNCVMLLN 240 APPNQTGLLH GTDVANLRDF RSVIDRIFAT NLASKARVSA SSTRGGDISS FRPDQVLNDD 300 LEAYWASEEG LTTPFLTLDL GSNKTFNVVK LQEAVHLGQR VQLYHVDVMQ DGRWKTVSVG 360 TTIGYKKLDR FEKVHSQLVR IYIDGARGTP LISAVGLYLD TWSALSLAAE STQVSE* 420 |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam00754 | F5_F8_type_C | 1.0e-6 | 278 | 389 | 119 | + F5/8 type C domain. This domain is also known as the discoidin (DS) domain family. | ||
| pfam01120 | Alpha_L_fucos | 6.0e-26 | 6 | 260 | 270 | + Alpha-L-fucosidase. | ||
| smart00812 | Alpha_L_fucos | 2.0e-27 | 6 | 260 | 274 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| COG3669 | COG3669 | 8.0e-58 | 6 | 398 | 414 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005975 | carbohydrate metabolic process |
| GO:0007155 | cell adhesion |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAH68057.1 | 0 | 5 | 403 | 83 | 481 | B0103C08-B0602B01.14 [Oryza sativa (indica cultivar-group)] |
| RefSeq | XP_001762481.1 | 0 | 5 | 416 | 47 | 458 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_002276131.1 | 0 | 5 | 416 | 93 | 502 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002313533.1 | 0 | 5 | 403 | 57 | 457 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002523703.1 | 0 | 5 | 406 | 106 | 510 | alpha-l-fucosidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3eyp_B | 0 | 5 | 398 | 54 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3eyp_A | 0 | 5 | 398 | 54 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3ues_B | 0 | 5 | 393 | 62 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3ues_A | 0 | 5 | 393 | 62 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3mo4_B | 0 | 5 | 393 | 64 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| BJ587030 | 196 | 222 | 417 | 0 |
| HO479002 | 400 | 5 | 398 | 0 |
| BJ170702 | 189 | 229 | 417 | 0 |
| CV735016 | 351 | 52 | 401 | 0 |
| DY300194 | 272 | 5 | 276 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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