| Basic Information | |
|---|---|
| Species | Malus domestica |
| Cazyme ID | MDP0000166406 |
| Family | GH29 |
| Protein Properties | Length: 458 Molecular Weight: 52021.7 Isoelectric Point: 6.7893 |
| Chromosome | Chromosome/Scaffold: 003154278 Start: 20706 End: 22769 |
| Description | alpha-L-fucosidase 1 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH29 | 41 | 339 | 0 |
| AQLKWQQREIIMFLHFGVNTFTDSEWGTGHESPGIFNPVGLDANQWARTASDAGISLMILTAKHHDGFCLWPSKYTDHSVANSPWRNGHGDVVHELVDAA NPRGIDIGLYLSPWDRHDRRYGHEIAYNQYYLAQLQELLSRYGGVKEIWFDGNKGKNAPNMSYYFTDWFSMVKELQSSINIFSDAGPDVRWVGNEQGFAG STCWSTINRTSLSIGNASIEDYLNKGDPKGTDWLPAECDVSIRDGWFWHKSESPKRLSKLLEIYYNSVGRNCVLLLNVPPNPTGLIADEDVQRLREFRS | |||
| Full Sequence |
|---|
| Protein Sequence Length: 458 Download |
| MAKIWCSLWI IAFFQLCTCT FSKLEQVPTP PLPILPLPTY AQLKWQQREI IMFLHFGVNT 60 FTDSEWGTGH ESPGIFNPVG LDANQWARTA SDAGISLMIL TAKHHDGFCL WPSKYTDHSV 120 ANSPWRNGHG DVVHELVDAA NPRGIDIGLY LSPWDRHDRR YGHEIAYNQY YLAQLQELLS 180 RYGGVKEIWF DGNKGKNAPN MSYYFTDWFS MVKELQSSIN IFSDAGPDVR WVGNEQGFAG 240 STCWSTINRT SLSIGNASIE DYLNKGDPKG TDWLPAECDV SIRDGWFWHK SESPKRLSKL 300 LEIYYNSVGR NCVLLLNVPP NPTGLIADED VQRLREFRSA IDAIFSTNLA EKCSIKVSSR 360 RGGKGGGFGP ENMLDNDHLW TYWAPRDDEK ESHWIEFRST GSDEGLRFNV IRIQEAIGLG 420 QRIKRHEIYV DGKRVVNGTT VGHKRLHRLG GELYMANL |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01120 | Alpha_L_fucos | 9.0e-32 | 52 | 337 | 324 | + Alpha-L-fucosidase. | ||
| smart00812 | Alpha_L_fucos | 7.0e-32 | 52 | 337 | 326 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| COG3669 | COG3669 | 7.0e-56 | 42 | 343 | 312 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_002270630.1 | 0 | 41 | 458 | 22 | 436 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002270674.1 | 0 | 29 | 450 | 7 | 427 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002318264.1 | 0 | 1 | 449 | 1 | 446 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002322431.1 | 0 | 1 | 449 | 1 | 447 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002510887.1 | 0 | 1 | 449 | 1 | 448 | alpha-l-fucosidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3eyp_B | 0 | 33 | 450 | 5 | 428 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3eyp_A | 0 | 33 | 450 | 5 | 428 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3ues_B | 0 | 38 | 449 | 19 | 449 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3ues_A | 0 | 38 | 449 | 19 | 449 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3mo4_B | 0 | 38 | 449 | 21 | 451 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
